Protein

Protein accession
A0A8S5VWP5 [UniProt]
Representative
8LHfr
Source
UniProt (cluster: phalp2_33582)
Protein name
Morphogenesis protein 1 hydrolase
Lysin probability
100%
PhaLP type
VAL
Probability: 99% (predicted by ML model)
Protein sequence
MAVELRYPRFDVTFFTETDQYHISYDTRDKLSGNRNADGTRKAQVSNNFMSESVISLTTKNAMEDDSAVFSFVLAGDVYWDRVLQANDAVVLRIDPDITSETPNNPILLVGLVSEIRLEGDYGENSKMYRITGQSFAKALMQFDLGVIQEVSVVLTDLGWLPDDAQEGIKMSGSSASQIAESLMKRFIQYMKFNFNGEGIDKFLEWELDSWTEAERLIDGTPYINYEGSLKQLLDDITAKPFNELFFDATPEGKCRMIMRRTPFDKADWEKLETFLVTSKDVISESLATNDVEAYSIYNISINNLYGTDSMMLGSKPQVFPDLVNKYGYKKLEVGNRYLEGAIIDKSSDNKEADTSPKAEEVDNEGVTGKQLFETEYALTLNYLQNYPNDVLRVRRNEVRTSLTQIDKRITENKADQLIDQYVDYQSLTKEKFSEITGIKESNIDEGNGKDKPSYDKVKKLLNSLSKDLGVTTIKENLMNKFNLTNNQALSLASEYKASGNLGKLKYEEIMANNPSDSSTVTGSDIKYVSEFTKRLANWYCENANFYSGDIVVKGNPKYRLGNRLFVQDEQNGELWEFYIESVEHSFSYSQGYQTTLGVTRGLQNGGNDRFTHLWGKSEDFSGGMLGEKELQALLDEQAKANKENEGSSSGGDGATGEKEYTAGAGTQLAVFPLDVINVTQGENGQFSHMGALAIDFSDGTPHKPYYAPFDCECVYTDSYSGVAWQSQKPVKCVDGSVTYVTLLCIHDNNWASNKVGDKKAKGEVLGHTGTAGQATGDHAHFEVSKNKWTGWSTSSAGVYYIQNPAHLYDVFSIKNNITGKTASVRNGGGYNWRSIDWDDKSGSGSGSKKSNRSKRSVRMLNATPQVAEEPVKKESIPQKKAKVVKEKPKTYKTVYGSNVAKEATKWAREHSKTESMYQSAFNFGNNNGEDPFEKEEIATDSAGLVWWSFYHAGAELAGGAIGVTTRSLLYDRQLETISSRGQKNESIFDTMLVGDLVWFNRGSHVGIYCGGGKFVACNGKGTMENNPKTGIVVVDMTKGYWWDKFDGTVRRYK
Physico‐chemical
properties
protein length:1054 AA
molecular weight:117690,7 Da
isoelectric point:5,23
hydropathy:-0,59
Representative Protein Details
Accession
8LHfr
Protein name
8LHfr
Sequence length
519 AA
Molecular weight
58338,01900 Da
Isoelectric point
5,06801
Sequence
MTTVKRMPEFDLKFVTEKNDYLIRYDARNPSSDTLAEKVISVTTKNAMSDDSAVFSIVVAGDMEWDKILDSNDVVILKIYPNLRVMMPDNVVVLVGLISEVRREGDYSNNSIIYRITGQSFAKSFMQFQLGVIQEVSVVITDIGWLPDSKADGVEFTGKTAAEIGKSITDRFKKYMKYNFNREYTMENFLDYSFSSWKDYEKLADPTPFINYEGSLKQLLDDVTAKPFNELFFESTSDEKCKMIMRRTPFNKEDWDKLPSYKISTETVIADSLAKGDTEAYSIFNVTSGNMAGATSVDLNSFPQYHQALVDKYGYKKLEVDNRYLFESSTDGSSTTEKADAGSKEKTKTVITYSKFNSFMRSYTSDQVRMNQSSIAKSLVDSYDKLTTSQANQLLAKYSAVGAISEADFKKIVGDIAEGDNTGTATLDFDSVNSWFSLNYNSLSEVSTNRDATIKAFVKNFANTDEDQATKIVALYISSQGVMTKEKFDAIIRSLLALALKTQIAQQVALVQHYSTSLK
Other Proteins in cluster: phalp2_33582
Total (incl. this protein): 135 Avg length: 801,2 Avg pI: 5,28
Protein ID Length (AA) pI
8LHfr 519 5,06801
8Mc3B 397 4,92489
A0A7S9SUM6 838 4,80974
A0A068CD38 795 5,14804
D9J0P7 872 5,28167
G9B1D1 723 5,13338
A0A0A0PLM7 665 5,24598
J9PV65 725 5,21614
A0A024B1S4 725 5,21392
A0A142F1E9 730 5,18095
A0A143FKX5 725 5,26769
G9J205 757 5,77492
U5PY14 718 5,51795
A0A0E3XDN6 1061 5,24063
A0A143FLJ0 725 5,27065
A0A516KMP4 755 5,12042
A0A516KND4 719 5,44685
A0A0K2FKY5 725 5,22012
A0A120HUN9 763 4,80650
A0A076G910 714 5,54012
A0A3B1EES3 719 5,66067
A0A1I9S608 757 5,67744
A0A2K9V6E5 725 5,32226
A0A0A0RNB0 704 4,89920
J9PLM4 746 5,18743
J9PS02 754 5,99472
L0LBX0 714 5,46396
A0A060AGJ6 795 5,14804
A0A3B8DXN4 839 4,80974
A0A140HM00 746 5,86518
A0A288TXT7 839 4,78149
A0A024B0J1 746 5,18743
A0A024B2T8 725 5,22012
A0A059T6T7 795 5,18897
A0A059T850 795 5,14804
A0A059T8P4 795 5,18897
A0A068CAS9 795 5,14804
A0A076G798 795 5,14804
A0A088FTF2 795 5,14804
A0A096XT07 1013 5,28531
A0A143FHQ0 725 5,22012
A0A143FJ36 746 5,18743
A0A143FNJ0 725 5,22012
A0A143FQR4 725 5,21614
A0A173H2M1 725 5,22012
A0A192YB29 725 5,27065
A0A1I9S580 725 5,27065
A0A1I9S708 725 5,27065
A0A218KDQ9 757 5,77754
A0A222Z2K4 725 5,21614
A0A222Z3V2 725 5,22012
A0A222Z4V1 746 5,17970
A0A222Z7T6 746 5,17970
A0A223LED7 746 5,18743
A0A2Z6FZC0 1061 5,24063
A0A2Z6FZV5 1061 5,24063
A0A345AXN1 725 5,26769
A0A345AYN0 746 5,18743
A0A346TP23 757 5,77754
A0A385E661 746 5,17970
A0A385E9L4 725 5,22012
A0A3G8F448 746 5,23563
A0A411B7M2 839 4,83839
A0A4D6DTM4 1061 5,26962
A0A4D6DUN9 1061 5,24063
A0A514A7X8 725 5,22012
A0A514U7K2 795 5,18897
A0A5B9MS53 763 5,87189
A0A5B9NQB8 761 5,58633
A0A5K7QTN2 1061 5,24063
A0A6B9STI0 1061 5,26962
A0A6C0RRZ9 764 4,80422
A0A6H2A7R8 795 5,14804
A0A6H2A896 795 5,14804
A0A6M9YZ91 795 5,15458
A0A6V7BC99 1061 5,27138
A0A6V7BCT9 1061 5,24063
A0A7D5JRL2 731 5,38410
A0A7G8ZZ30 839 4,87573
A0A7G9A3K3 838 4,80974
A0A7G9A539 795 5,14804
A0A7G9A5N7 795 5,14804
A0A7R7EQI7 1061 5,24063
A0A7R7ER43 1061 5,24063
A0A7R7IFP5 1061 5,24063
A0A7S5SMR1 718 4,69464
A0A858EAZ2 795 5,14804
A0A858EEE9 795 5,14804
A0A8D6XUK6 839 4,89557
A0A8E7L2H9 839 4,80332
A8AST2 795 5,11610
A8E282 1061 5,24063
Q30LB6 795 5,14804
S4U6W0 795 5,14804
S6ANI5 670 5,64499
A0A5C2IHG1 795 5,14804
A0A0A0RS48 767 4,85311
A0A024B187 746 5,23563
A0A0A0PUF6 665 5,24598
A0A679L8Z2 839 4,82247
A0A8S5VKK7 1061 5,23825
A0A976MF92 873 5,11798
A0A9E7DTK6 1061 5,30003
A0A9E7DUC4 1061 5,30003
A0A9E7DV47 839 4,85691
A0A9E7SHM3 1061 5,26962
A0AA48X9T8 789 5,92606
A0AA96KRU1 715 5,34391
A0AAD1KWB2 797 5,83108
A0AAE7RFF5 1061 5,26962
A0AAE7X0N1 718 5,88684
A0AAE8BPE8 718 5,77049
A0AAE8BPU3 718 5,77049
A0AAE8YPC9 757 5,67744
A0AAE9CB06 725 5,27065
A0AAE9CCT1 737 5,86609
A0AAE9H251 670 5,55569
A0AAE9H3C4 719 5,51460
A0AAE9H3L4 670 5,55575
A0AAE9H3P6 719 5,51460
A0AAE9H3S6 670 5,55569
A0AAE9H4J6 719 5,58866
A0AAE9JUJ4 838 4,76398
A0AAE9JUM3 839 4,87601
A0AAE9KJV4 719 5,51460
A0AAE9YEZ6 670 5,63959
A0AAF0BY11 719 5,67255
A0AAF0BZN7 670 5,85518
A0AAF0C0M9 719 5,76759
A0AAX4LXG2 872 5,28167
A0AAX4PS55 1061 5,26962
A0AAX4PTI4 1061 5,26962
A0AAX4PTM0 1061 5,26962
B6DQH7 455 5,87308
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_37189
1QZtJ
 98 44,7% 516 6.740E-211
2 phalp2_28907
5tXTi
 21 22,7% 544 2.544E-46
3 phalp2_13435
4E5Bh
 16 25,2% 341 3.796E-37

Domains

Domains [InterPro]

No domain annotations available.

Taxonomy

  Name Taxonomy ID Lineage
Phage Herelleviridae sp
[NCBI] 		2831613 Herelleviridae >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK024700 [NCBI]
CDS location
range 24969 -> 28133
strand +
CDS
ATGGCAGTAGAATTAAGATACCCAAGGTTTGACGTGACTTTTTTTACAGAGACAGACCAATACCATATATCTTATGATACACGAGATAAGCTATCAGGAAACAGAAATGCAGATGGTACAAGAAAAGCACAAGTAAGTAACAATTTTATGTCTGAGTCTGTTATTAGTTTAACAACAAAAAATGCAATGGAGGACGACAGTGCAGTATTCTCTTTTGTATTAGCAGGAGATGTTTACTGGGATAGAGTACTACAAGCTAATGATGCAGTCGTATTAAGAATAGACCCTGACATCACTTCTGAAACACCAAATAACCCTATATTACTTGTAGGTCTAGTCTCAGAAATTAGACTAGAAGGGGACTACGGGGAAAACTCAAAAATGTATCGTATTACAGGTCAATCCTTCGCTAAAGCACTGATGCAATTTGACTTAGGGGTTATCCAAGAAGTAAGTGTTGTACTAACCGACTTAGGTTGGCTACCTGATGATGCTCAAGAAGGCATCAAGATGTCTGGTAGTAGTGCTAGCCAAATTGCGGAAAGTCTAATGAAACGTTTTATACAATATATGAAGTTTAATTTTAACGGTGAGGGAATTGATAAGTTTTTAGAGTGGGAGTTAGATAGTTGGACAGAGGCAGAGAGGTTGATTGACGGAACACCTTACATTAATTATGAAGGCTCCTTAAAACAACTTTTGGATGATATAACAGCTAAGCCATTTAATGAATTATTCTTTGATGCAACACCCGAAGGTAAATGTCGTATGATTATGAGACGGACTCCTTTCGATAAAGCAGACTGGGAGAAGCTAGAAACATTCTTAGTAACTTCTAAAGACGTAATATCAGAGTCCTTAGCAACAAATGATGTAGAGGCATATTCTATCTATAACATTAGTATTAACAACTTGTATGGTACAGACTCTATGATGTTGGGTTCTAAACCACAAGTGTTCCCTGACTTAGTAAACAAGTACGGTTATAAAAAATTAGAAGTAGGCAACAGATACCTAGAGGGGGCTATAATAGATAAAAGTAGTGATAATAAAGAGGCGGACACTTCCCCTAAAGCAGAGGAAGTAGATAATGAGGGAGTGACAGGTAAGCAACTGTTTGAAACAGAATATGCGCTTACCTTAAACTACTTACAGAACTACCCGAATGATGTCTTACGAGTAAGAAGAAACGAAGTAAGAACTTCTCTTACACAAATAGACAAACGTATCACAGAAAATAAAGCAGACCAACTAATCGACCAATATGTAGACTACCAAAGTTTAACGAAAGAGAAGTTCTCTGAGATAACGGGTATTAAAGAAAGCAACATAGACGAGGGTAACGGAAAAGACAAACCTAGCTATGATAAAGTAAAAAAACTATTAAACAGCTTAAGTAAGGATTTAGGGGTAACCACTATTAAGGAAAACCTAATGAACAAGTTTAACCTAACAAATAACCAAGCGTTGAGTTTAGCTAGTGAGTATAAGGCAAGTGGTAATTTAGGTAAGCTTAAGTATGAAGAGATAATGGCTAACAACCCTAGTGACAGTTCCACTGTAACTGGCTCAGATATTAAATATGTATCAGAGTTTACTAAAAGATTAGCTAACTGGTACTGTGAAAATGCAAACTTTTATAGTGGAGACATTGTTGTGAAAGGAAACCCTAAGTATCGTTTAGGTAACAGACTATTTGTACAAGATGAACAAAATGGTGAGCTATGGGAGTTCTATATAGAATCTGTAGAGCACTCTTTCTCATATAGCCAAGGTTACCAAACAACGTTAGGAGTAACTAGAGGACTGCAAAATGGAGGTAACGATAGGTTTACCCATCTATGGGGCAAATCCGAAGACTTCTCTGGTGGTATGTTAGGAGAGAAAGAGCTTCAAGCGTTACTAGACGAACAAGCAAAAGCAAACAAGGAGAACGAGGGCTCTAGCTCAGGAGGAGACGGAGCAACTGGGGAGAAAGAGTATACAGCGGGAGCAGGAACTCAGCTAGCAGTATTCCCATTGGATGTGATTAACGTCACCCAAGGAGAAAATGGACAGTTCAGTCATATGGGGGCGCTAGCAATTGACTTTTCAGATGGAACTCCACATAAGCCTTATTATGCCCCATTTGACTGTGAATGTGTTTATACAGATTCTTACTCAGGTGTTGCGTGGCAGTCGCAGAAACCAGTTAAATGTGTTGATGGTAGTGTTACTTACGTAACTTTACTATGCATTCATGATAACAACTGGGCAAGCAATAAAGTAGGGGATAAGAAAGCTAAAGGAGAAGTTTTAGGGCATACAGGAACAGCAGGTCAAGCAACAGGAGACCATGCGCATTTTGAGGTATCCAAAAACAAATGGACTGGATGGAGTACAAGTAGTGCAGGTGTTTACTATATTCAAAATCCTGCCCACCTATACGATGTTTTCTCTATCAAAAACAACATAACAGGAAAAACTGCAAGTGTGCGTAACGGCGGAGGATACAACTGGCGTAGTATTGACTGGGACGATAAATCAGGTTCTGGCTCAGGTAGCAAGAAGAGCAATAGGAGTAAAAGGTCAGTGAGAATGTTAAACGCAACACCTCAAGTAGCAGAGGAGCCAGTTAAAAAAGAAAGCATACCTCAAAAGAAAGCCAAAGTTGTAAAAGAAAAACCAAAAACTTATAAAACTGTGTACGGAAGTAATGTAGCTAAAGAAGCAACGAAATGGGCTAGAGAACATTCTAAAACAGAATCAATGTACCAGTCAGCATTTAACTTCGGGAACAATAATGGAGAAGACCCATTTGAAAAAGAAGAGATAGCTACTGATAGTGCAGGACTAGTCTGGTGGAGCTTCTACCATGCAGGTGCAGAGTTGGCAGGAGGAGCTATTGGTGTAACTACACGTTCCCTTCTATATGATAGACAGCTAGAGACAATTAGTAGTAGAGGTCAAAAGAACGAATCCATATTTGATACTATGCTAGTAGGAGACCTAGTATGGTTTAACCGAGGAAGCCACGTAGGAATCTACTGTGGTGGTGGTAAATTTGTGGCTTGTAACGGCAAAGGTACGATGGAGAACAACCCTAAAACTGGTATTGTTGTAGTAGATATGACAAAAGGATACTGGTGGGATAAATTCGATGGTACAGTAAGGAGATATAAGTAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008234 cysteine-type peptidase activity molecular function None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (8LHfr) rather than this protein.
PDB ID
8LHfr
Method AlphaFoldv2
Resolution 76.73
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50