Protein

Protein accession

A0A096XT07 [UniProt]

Representative

8LHfr

Source

UniProt (cluster: phalp2_33582)

Protein name

Tail lysin

Lysin probability

100%

PhaLP type

VAL
Probability: 99% (predicted by ML model)

Protein sequence

MAESVISLTTKNALEDDSAVFSFVLAGDVYWDRVLNANDAVILKIDPDTSSTKKSDNPVLLVGLISEVRLEGDYGENSKMYRITGQSFAKALMQFDLGVIQEVSVVLTDLGWLPDDAQEGIKMSGSSASQIAESLMKRFLQYMKFNFNGQGIDKFLEWELDSWTEAERLIDSTPYINYEGSLKQLIDDVTAKPFNELYFDATPEGKCRMIMRRTPFDKSDWEKLQTYTVTSAEVISESVAVNDTEAYSIFNISINNLYGTDSMMLGSKPQVFPDLVSKYGYKKLEVPNRYLEGAIIDKSNSGDKANTKPESDNDSKESDGSTAKQMFDREYALVLNYLKGYPVDVLRVKKSNVRTSITQVDRRITDNEADKIIDHYITNQALSKEDFSKFTGITEENIEEGNGKVEPTYTAVRDFLNGLDKNLGVSSIKEKLMNYFNLIPNQATSIASEYKAQGNLGKLKYEEIMENNPSDSSTVTGSDKRFVSEFTKRLANWYCENANFYSGDIVVKGDPKYRLGNRLFVQDEQNGELWEYYIESVEHSFSYTQGYITTLGVTRGLQNGGNDRFTHLWGKSEDFSGGMLGEKTLQALLDEQAEANSKNDGGSDSGGSSGKEYTAGAGTQLAVFPLDVINVTQGENGGYSHMGALAIDFSDGTPHKPYYAPFDCECVYTDSYSGVAWQSQKPVKCVDGSVTYVTLLCVHDNNWASNKVGDKKAKGEVIGHSGTAGQASGDHAHFEVSKGKWQGWSTSSAGVYFIKNPSHLYDVFSIKNNVTGKTTKIMNGGGYNWRSIDWDDKSGSGSGKKKTVGARAMATPFGFRMMRSAPVEPEEPKVVKQIETKTVVEKKPKVEVKKLPILYGNNIATEATKWGRAHSKTESTFQSAFNFGANTDKDPFEEDIIATDSAGFVWWCFYHAGISLSGGARMVTTRSLLYDNQLQTISTRGQKSLELFDKMKVGDLVWFNRASHVGIYCGEGKMVSCNGKGNMDESPKTGIVIVDMSKGYWWNAFDGNVRRYK

Physico‐chemical properties

protein length:	1013 AA
molecular weight:	112524,5 Da
isoelectric point:	5,29
hydropathy:	-0,51

Representative Protein Details

Accession

8LHfr

Protein name

8LHfr

Sequence length

519 AA

Molecular weight

58338,01900 Da

Isoelectric point

5,06801

Sequence

MTTVKRMPEFDLKFVTEKNDYLIRYDARNPSSDTLAEKVISVTTKNAMSDDSAVFSIVVAGDMEWDKILDSNDVVILKIYPNLRVMMPDNVVVLVGLISEVRREGDYSNNSIIYRITGQSFAKSFMQFQLGVIQEVSVVITDIGWLPDSKADGVEFTGKTAAEIGKSITDRFKKYMKYNFNREYTMENFLDYSFSSWKDYEKLADPTPFINYEGSLKQLLDDVTAKPFNELFFESTSDEKCKMIMRRTPFNKEDWDKLPSYKISTETVIADSLAKGDTEAYSIFNVTSGNMAGATSVDLNSFPQYHQALVDKYGYKKLEVDNRYLFESSTDGSSTTEKADAGSKEKTKTVITYSKFNSFMRSYTSDQVRMNQSSIAKSLVDSYDKLTTSQANQLLAKYSAVGAISEADFKKIVGDIAEGDNTGTATLDFDSVNSWFSLNYNSLSEVSTNRDATIKAFVKNFANTDEDQATKIVALYISSQGVMTKEKFDAIIRSLLALALKTQIAQQVALVQHYSTSLK

Other Proteins in cluster: phalp2_33582

Protein ID	Length (AA)	pI
Total (incl. this protein): 135	Avg length: 801,2	Avg pI: 5,28

8LHfr	519	5,06801
8Mc3B	397	4,92489
A0A7S9SUM6	838	4,80974
A0A068CD38	795	5,14804
D9J0P7	872	5,28167
G9B1D1	723	5,13338
A0A0A0PLM7	665	5,24598
J9PV65	725	5,21614
A0A024B1S4	725	5,21392
A0A142F1E9	730	5,18095
A0A143FKX5	725	5,26769
G9J205	757	5,77492
U5PY14	718	5,51795
A0A0E3XDN6	1061	5,24063
A0A143FLJ0	725	5,27065
A0A516KMP4	755	5,12042
A0A516KND4	719	5,44685
A0A0K2FKY5	725	5,22012
A0A120HUN9	763	4,80650
A0A076G910	714	5,54012
A0A3B1EES3	719	5,66067
A0A1I9S608	757	5,67744
A0A2K9V6E5	725	5,32226
A0A0A0RNB0	704	4,89920
J9PLM4	746	5,18743
J9PS02	754	5,99472
L0LBX0	714	5,46396
A0A060AGJ6	795	5,14804
A0A3B8DXN4	839	4,80974
A0A140HM00	746	5,86518
A0A288TXT7	839	4,78149
A0A024B0J1	746	5,18743
A0A024B2T8	725	5,22012
A0A059T6T7	795	5,18897
A0A059T850	795	5,14804
A0A059T8P4	795	5,18897
A0A068CAS9	795	5,14804
A0A076G798	795	5,14804
A0A088FTF2	795	5,14804
A0A143FHQ0	725	5,22012
A0A143FJ36	746	5,18743
A0A143FNJ0	725	5,22012
A0A143FQR4	725	5,21614
A0A173H2M1	725	5,22012
A0A192YB29	725	5,27065
A0A1I9S580	725	5,27065
A0A1I9S708	725	5,27065
A0A218KDQ9	757	5,77754
A0A222Z2K4	725	5,21614
A0A222Z3V2	725	5,22012
A0A222Z4V1	746	5,17970
A0A222Z7T6	746	5,17970
A0A223LED7	746	5,18743
A0A2Z6FZC0	1061	5,24063
A0A2Z6FZV5	1061	5,24063
A0A345AXN1	725	5,26769
A0A345AYN0	746	5,18743
A0A346TP23	757	5,77754
A0A385E661	746	5,17970
A0A385E9L4	725	5,22012
A0A3G8F448	746	5,23563
A0A411B7M2	839	4,83839
A0A4D6DTM4	1061	5,26962
A0A4D6DUN9	1061	5,24063
A0A514A7X8	725	5,22012
A0A514U7K2	795	5,18897
A0A5B9MS53	763	5,87189
A0A5B9NQB8	761	5,58633
A0A5K7QTN2	1061	5,24063
A0A6B9STI0	1061	5,26962
A0A6C0RRZ9	764	4,80422
A0A6H2A7R8	795	5,14804
A0A6H2A896	795	5,14804
A0A6M9YZ91	795	5,15458
A0A6V7BC99	1061	5,27138
A0A6V7BCT9	1061	5,24063
A0A7D5JRL2	731	5,38410
A0A7G8ZZ30	839	4,87573
A0A7G9A3K3	838	4,80974
A0A7G9A539	795	5,14804
A0A7G9A5N7	795	5,14804
A0A7R7EQI7	1061	5,24063
A0A7R7ER43	1061	5,24063
A0A7R7IFP5	1061	5,24063
A0A7S5SMR1	718	4,69464
A0A858EAZ2	795	5,14804
A0A858EEE9	795	5,14804
A0A8D6XUK6	839	4,89557
A0A8E7L2H9	839	4,80332
A8AST2	795	5,11610
A8E282	1061	5,24063
Q30LB6	795	5,14804
S4U6W0	795	5,14804
S6ANI5	670	5,64499
A0A5C2IHG1	795	5,14804
A0A0A0RS48	767	4,85311
A0A024B187	746	5,23563
A0A0A0PUF6	665	5,24598
A0A679L8Z2	839	4,82247
A0A8S5VKK7	1061	5,23825
A0A8S5VWP5	1054	5,23330
A0A976MF92	873	5,11798
A0A9E7DTK6	1061	5,30003
A0A9E7DUC4	1061	5,30003
A0A9E7DV47	839	4,85691
A0A9E7SHM3	1061	5,26962
A0AA48X9T8	789	5,92606
A0AA96KRU1	715	5,34391
A0AAD1KWB2	797	5,83108
A0AAE7RFF5	1061	5,26962
A0AAE7X0N1	718	5,88684
A0AAE8BPE8	718	5,77049
A0AAE8BPU3	718	5,77049
A0AAE8YPC9	757	5,67744
A0AAE9CB06	725	5,27065
A0AAE9CCT1	737	5,86609
A0AAE9H251	670	5,55569
A0AAE9H3C4	719	5,51460
A0AAE9H3L4	670	5,55575
A0AAE9H3P6	719	5,51460
A0AAE9H3S6	670	5,55569
A0AAE9H4J6	719	5,58866
A0AAE9JUJ4	838	4,76398
A0AAE9JUM3	839	4,87601
A0AAE9KJV4	719	5,51460
A0AAE9YEZ6	670	5,63959
A0AAF0BY11	719	5,67255
A0AAF0BZN7	670	5,85518
A0AAF0C0M9	719	5,76759
A0AAX4LXG2	872	5,28167
A0AAX4PS55	1061	5,26962
A0AAX4PTI4	1061	5,26962
A0AAX4PTM0	1061	5,26962
B6DQH7	455	5,87308

Similar Clusters (pHMM search)

#	Cluster	# Members	Identity (%)	Alignment Length	E-value
1	phalp2_37189 1QZtJ	98	44,7%	516	6.740E-211
2	phalp2_28907 5tXTi	21	22,7%	544	2.544E-46
3	phalp2_13435 4E5Bh	16	25,2%	341	3.796E-37

Domains

Domains [InterPro]

No domain annotations available.

Taxonomy

	Name	Taxonomy ID	Lineage
Phage	Enterococcus phage ECP3 [NCBI]	1498168	Herelleviridae > Kochikohdavirus > Kochikohdavirus ECP3
Host	Enterococcus faecalis [NCBI]	1351	Firmicutes > Bacilli > Lactobacillales > Enterococcaceae > Enterococcus >

Coding sequence (CDS)

CDS Source ID

[NCBI]

CDS Source

KJ801817 [NCBI]

CDS location

range 67966 -> 71007
strand -

CDS

ATGGCAGAGTCTGTAATTAGTTTAACTACAAAAAATGCTTTAGAGGATGATAGTGCAGTCTTCTCATTCGTATTAGCAGGGGACGTGTATTGGGATAGAGTACTAAATGCTAATGATGCAGTTATTCTTAAAATAGACCCAGATACTTCCTCCACTAAAAAATCAGATAACCCTGTACTACTAGTTGGTTTAATATCTGAGGTTAGACTAGAGGGTGACTATGGGGAAAACTCTAAGATGTACAGGATAACAGGACAGTCTTTCGCAAAGGCGCTAATGCAGTTTGACTTAGGTGTTATTCAGGAAGTAAGTGTAGTTTTGACAGATTTAGGTTGGTTGCCTGACGATGCACAAGAAGGTATAAAAATGTCTGGTAGTAGTGCAAGTCAAATAGCAGAAAGCTTAATGAAAAGATTTTTACAATATATGAAATTTAATTTTAATGGTCAAGGTATAGATAAGTTCTTAGAGTGGGAGCTAGATAGTTGGACAGAGGCGGAGAGACTAATAGATAGTACCCCTTACATAAACTATGAAGGTTCTTTAAAGCAACTTATAGATGATGTAACCGCTAAACCGTTTAACGAATTATATTTCGATGCAACACCAGAGGGTAAATGCAGAATGATTATGCGTAGAACCCCATTTGATAAATCTGATTGGGAAAAATTACAAACCTACACAGTAACATCTGCAGAAGTAATATCTGAATCTGTAGCAGTTAACGATACAGAAGCTTACTCTATATTTAACATATCTATTAATAACTTGTATGGGACTGACTCTATGATGTTAGGTTCTAAACCACAAGTATTCCCTGATTTAGTTTCTAAATATGGTTATAAGAAACTAGAAGTACCTAATAGGTATTTAGAAGGAGCAATTATAGATAAGAGTAACAGTGGAGATAAAGCTAACACAAAACCCGAAAGTGATAATGATAGTAAAGAGAGCGATGGCTCAACAGCTAAACAGATGTTTGACAGAGAGTACGCTCTTGTCTTAAACTATCTAAAAGGGTATCCTGTTGATGTGCTAAGAGTTAAAAAAAGTAATGTAAGAACATCAATAACACAGGTAGACAGACGTATAACAGATAACGAAGCAGATAAAATTATAGACCACTATATTACAAATCAAGCATTAAGTAAAGAAGACTTTTCTAAATTTACAGGAATAACCGAAGAAAATATAGAAGAGGGTAACGGTAAAGTAGAACCTACATATACCGCAGTTAGGGACTTCCTTAATGGGTTAGATAAAAACCTAGGAGTATCTAGCATAAAAGAGAAATTAATGAACTACTTCAATTTGATACCTAACCAAGCCACATCTATTGCTAGTGAATACAAAGCACAAGGTAACTTAGGTAAACTAAAATATGAAGAAATAATGGAGAATAACCCAAGTGATAGCTCAACCGTCACTGGTTCAGATAAACGATTTGTTTCTGAGTTCACTAAAAGACTAGCAAATTGGTACTGTGAAAACGCTAATTTCTACAGTGGGGATATTGTAGTTAAAGGTGACCCTAAATATAGATTAGGTAACCGTTTGTTTGTTCAAGATGAGCAAAATGGTGAGTTGTGGGAATACTACATAGAATCAGTAGAACACTCGTTCTCCTATACACAAGGGTATATCACTACTCTTGGGGTCACTAGAGGTTTACAAAATGGAGGAAACGATAGATTCACTCATTTATGGGGTAAATCTGAGGACTTCTCCGGAGGTATGCTAGGTGAGAAAACCTTGCAAGCACTACTAGACGAACAAGCAGAAGCAAACAGTAAAAATGATGGAGGCTCTGATAGTGGAGGTAGCTCAGGTAAAGAGTATACAGCAGGTGCAGGAACTCAGCTAGCGGTATTCCCATTAGACGTAATTAATGTAACTCAGGGAGAAAATGGTGGATACAGCCACATGGGAGCACTTGCAATAGACTTTTCAGATGGTACTCCTCATAAACCTTACTATGCACCATTTGACTGCGAATGTGTGTACACTGACTCTTACTCAGGGGTTGCATGGCAATCTCAAAAGCCTGTTAAATGTGTAGATGGTAGTGTTACTTACGTAACACTATTATGCGTACACGACAACAACTGGGCAAGCAACAAAGTAGGGGATAAGAAAGCTAAAGGGGAAGTAATAGGGCACTCAGGGACTGCAGGACAAGCATCAGGAGACCATGCCCACTTCGAGGTGTCTAAAGGTAAATGGCAAGGTTGGAGCACAAGCAGTGCGGGAGTTTACTTTATAAAAAATCCTTCTCATTTATACGATGTATTTTCTATAAAAAATAATGTAACTGGAAAAACAACTAAAATTATGAATGGTGGAGGGTACAATTGGCGTAGTATAGACTGGGACGATAAATCTGGTTCAGGTTCTGGAAAGAAAAAGACAGTTGGTGCTAGAGCCATGGCTACCCCATTCGGATTTCGTATGATGCGTAGCGCTCCGGTAGAACCAGAAGAGCCGAAAGTTGTTAAACAAATAGAAACTAAAACAGTTGTTGAAAAGAAACCAAAAGTAGAAGTTAAAAAGCTCCCAATACTTTATGGGAATAACATTGCCACAGAAGCAACTAAATGGGGAAGAGCTCACTCGAAAACAGAGTCCACATTCCAATCTGCCTTCAATTTTGGAGCTAATACAGATAAAGACCCATTTGAGGAAGACATTATAGCAACAGACAGCGCAGGATTTGTTTGGTGGTGTTTCTACCATGCGGGCATATCGCTATCTGGTGGAGCTAGAATGGTTACCACTCGTTCACTACTCTATGATAACCAATTACAAACTATCTCTACTAGAGGTCAGAAGTCTTTAGAGTTATTTGATAAGATGAAGGTAGGAGATTTAGTTTGGTTTAACAGAGCTAGCCATGTAGGGATATATTGTGGTGAGGGTAAGATGGTCTCTTGTAATGGAAAAGGTAACATGGATGAGTCCCCAAAAACAGGTATTGTTATTGTCGACATGTCTAAAGGTTATTGGTGGAACGCTTTTGACGGAAATGTACGTAGATATAAATAA

Gene Ontology

	Description	Category	Evidence (source)
GO:0001897	symbiont-mediated cytolysis of host cell	biological process	None (UniProt)
GO:0008234	cysteine-type peptidase activity	molecular function	None (UniProt)
GO:0042742	defense response to bacterium	biological process	None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (8LHfr) rather than this protein.

PDB ID

8LHfr

Method AlphaFoldv2

Resolution 76.73

Chain position -

Download PDB

Model Confidence

Very high
pLDDT > 90

High
90 > pLDDT > 70

Low
70 > pLDDT > 50

Very low
pLDDT < 50