Protein

Protein accession
A0A8S0I168 [UniProt]
Representative
8gQfh
Source
UniProt (cluster: phalp2_22754)
Protein name
Peptidase M23 domain-containing protein
Lysin probability
100%
PhaLP type
endolysin
Probability: 92% (predicted by ML model)
Protein sequence
MFGAPRGGRSHAGVDLTEAPPWGSDPKIPVVAAIAGSVLAERYKAGQTYYSGMMIRGEDGHDQRYLHMEPSVKPGQEVNAGDQIGRLYDDRDNSHLHFEVYKNGKGGPLNPSLIYPSLFKAGSTGGGQMTNPTAFSGASVTSPGQNKPPQAAIQSMGDMQRIQIQPSLVKMVSSVSSLLKRQE
Physico‐chemical
properties
protein length:183 AA
molecular weight:19569,8 Da
isoelectric point:8,83
hydropathy:-0,53
Representative Protein Details
Accession
8gQfh
Protein name
8gQfh
Sequence length
725 AA
Molecular weight
77769,77220 Da
Isoelectric point
9,40911
Sequence
MKDGEKPTQLEEGEEPEEPQQQLARGGKVKTPQKALGGFINGPQSGYPVSLDGGRSTAFIGHGREYVARKSDGGAFVVPINTPGTKTQPHLTQKRVQEAKSQGYSVPGMAIGGDYLKAVKENDRTQGDNSAKKIFLHWSAGHRDGTNFYKGHGYHTYIPSSGQPVRKAPFGKQGAPYHTYGRPQTQSAAIGVAGMSTANNENGKDWGSQAITPNQYKGMAKEAAAIATAWGWKPSDITDKRVRTHAEEYRDYPNWYHRNNSSHYRWDLSRLYAGEPAFSGGPKIRNMIKQEMGGAAGDAKDEPDAKDGARQVQQPRGIMSNFLGAIDAMTGGRTDFDGMGGGQRNITNPDQKGEKEANTREAQESKDKKQGMVFPLPNGRFAAGPRQVYGAGRSYGGHAGIDLTEMPPFGSDPKIPVVAAISGTVLKEKYKGGQTYYSGMMIQGEDGYDQRYLHMEPTVKPGQKVQAGQVIGKLYDDADNTHLHFEVYKRGKGGHLNPAQIYPDLFKPGATGGGGEIQGSVTPPGATNPPDAPGTDSAANPSGAANVAKTIIPKASSAMSFEERYGSTRYTNDNFELATKKEEERRQQLQAMLPNMSNAMGPGAPQAGQQQGASAKQLQKITKDRNNARQLVQNRTQEMIQQVMAQVAKQNGMNQQMAQQASLQISQMMQQSMAQQNAAKNAPPQVVGGGGGGAAGGRGTELVGGIVKTTASALNSNLNPLKGLF
Other Proteins in cluster: phalp2_22754
Total (incl. this protein): 42 Avg length: 875,8 Avg pI: 9,74
Protein ID Length (AA) pI
8gQfh 725 9,40911
12e5g 951 10,01628
1SvsA 878 9,61767
1UKce 878 9,58324
1UPxn 936 9,82958
1VXYn 746 9,35535
1kubg 907 9,68259
1sg1J 1025 9,85265
1t6Ej 876 9,75763
1tBpm 868 9,75821
1tdnp 1013 9,89301
1yYDy 954 10,06185
1zxHu 1021 9,86071
26bbd 936 9,69509
27pb5 934 9,67569
2h3Mf 931 9,75621
3BUNg 982 10,04000
3xdTT 844 9,80617
4R93f 880 9,64352
4RGyd 1013 9,68297
4uoaU 695 9,49073
4upd8 881 9,61148
4ux0B 936 9,87419
4x7E6 727 9,72346
6O4lA 955 10,07707
7AkSc 868 9,85504
7PyJU 879 9,53225
7p5S1 1012 9,68297
8CxDj 982 10,04000
8Dnqa 855 9,79818
8F2fa 855 9,79818
8GEy8 662 9,55146
8GR1v 935 9,83712
8HqvF 867 9,86239
8LSV4 936 9,68265
8c04G 855 9,79818
8gzqH 935 9,83712
8xNJz 669 9,51961
dUmV 947 10,06476
r2y1 973 9,97521
M4QQL7 879 9,53225
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_21079
8LRzV
 133 33,1% 763 4.774E-78
2 phalp2_32545
1rZh9
 26 26,1% 584 3.609E-22

Domains

Domains [InterPro]

No domain annotations available.

Taxonomy

  Name Taxonomy ID Lineage
Phage Caudoviricetes sp
[NCBI] 		2832643 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
LC629490 [NCBI]
CDS location
range 140474 -> 141025
strand +
CDS
GTGTTTGGCGCACCAAGAGGAGGAAGAAGTCATGCAGGTGTAGACTTAACTGAAGCACCTCCTTGGGGATCAGATCCAAAGATTCCTGTTGTTGCTGCTATTGCAGGATCAGTGTTAGCGGAAAGATATAAAGCAGGTCAAACATACTACTCAGGTATGATGATCAGAGGTGAAGATGGTCATGATCAAAGATACTTGCACATGGAACCTAGTGTCAAACCTGGGCAGGAAGTCAATGCAGGTGACCAGATTGGTAGACTTTACGATGATAGAGACAACAGTCACCTACACTTTGAGGTATACAAAAACGGTAAGGGTGGACCTCTAAATCCATCTCTCATCTATCCTAGTCTGTTCAAAGCAGGATCTACAGGTGGAGGACAGATGACTAATCCTACTGCTTTCAGTGGTGCTTCTGTAACAAGTCCTGGTCAGAACAAACCTCCTCAAGCTGCCATTCAATCGATGGGTGATATGCAGAGAATACAGATACAACCTTCTCTGGTCAAGATGGTATCATCAGTCAGTTCTCTGCTGAAAAGACAAGAGTAG

Gene Ontology

Description Category Evidence (source)
GO:0004222 metalloendopeptidase activity molecular function None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (8gQfh) rather than this protein.
PDB ID
8gQfh
Method AlphaFoldv2
Resolution 61.53
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50