Protein

Protein accession

M4QQL7 [UniProt]

Representative

8gQfh

Source

UniProt (cluster: phalp2_22754)

Protein name

Peptidase M23 domain-containing protein

Lysin probability

97%

PhaLP type

VAL
Probability: 99% (predicted by ML model)

Protein sequence

MAKAAVQKGSKINVYKVVSIKEPDARMKKKDPNDYETAKGLNKTTVAINNLGATINGMNAMVADLKQVSLDRLEAANKDKPKMDPKYGTTKKGAGGILGSIAKGFVKTGGSFLGGLLKLLGGMFKLFVVLPILNWLSKEENQQKVAGALEVMAKIGKFIWEWAKFGITNTIDGLYKLLSDDSSWMDRIVGFGQAFLGFASIFIGMKGIAWLLNPIKVVKGITTAIRALIKFATNRGLSSVTGRRGRKGRGFAAGGALATTMTVAPMVMMPQMAKGGWISGPMSGYPVSLDGGRSTSFIGHGTEYVSRKAGGQAFVTPYDTPATRRNPGLTAMRQSEAKRKGFAEGGEVKESLNLTEDQFRNLAFGVSGEAQRGTDDEFGVAAAILNRVADPRYPNSIMQVLSAPDQYEAYHKGKMKFDDQLQDRLSSQKGQEGIIAALRELKGRTDFKGTAMYKYMGADDIKFSRKGNFYHYPEQKAKSDPPPDTIPTHYLRFIQNQEASDDQQRGESNDRAAVGVMGKLSSALSGVTNVLSNIFLGGPASAAENPGVVDPPPKKLESEANNKEGANASAGIESGSLGEKVFPLPKGRFQATARQVFGASRGGRSHAGVDLTEAPPWGSDPKIPVVAAIAGSVLAERYKAGQTYYSGMMIRGQDGHDQRYLHMEPAVKPGQEVNAGDQIGRLYDDGDNSHLHFEVYKNGKGGPLNPSLIYPSMFKAGTAGGGQMTNPTAFQSTSSVTSPGQNKPPQAAIQSMGDMSREEDTTFSGQDGIISQFSAEKTRATELQKATDDRDKERENFKAGVENAVMQASQQVQRSNQQSAAAIQQSQQGVQQAAQSGGGGKDVITGGLPGIGNVNINGVMKTTAYALNSNNNFMRGILR

Physico‐chemical properties

protein length:	879 AA
molecular weight:	94087,5 Da
isoelectric point:	9,53
hydropathy:	-0,45

Representative Protein Details

Accession

8gQfh

Protein name

8gQfh

Sequence length

725 AA

Molecular weight

77769,77220 Da

Isoelectric point

9,40911

Sequence

MKDGEKPTQLEEGEEPEEPQQQLARGGKVKTPQKALGGFINGPQSGYPVSLDGGRSTAFIGHGREYVARKSDGGAFVVPINTPGTKTQPHLTQKRVQEAKSQGYSVPGMAIGGDYLKAVKENDRTQGDNSAKKIFLHWSAGHRDGTNFYKGHGYHTYIPSSGQPVRKAPFGKQGAPYHTYGRPQTQSAAIGVAGMSTANNENGKDWGSQAITPNQYKGMAKEAAAIATAWGWKPSDITDKRVRTHAEEYRDYPNWYHRNNSSHYRWDLSRLYAGEPAFSGGPKIRNMIKQEMGGAAGDAKDEPDAKDGARQVQQPRGIMSNFLGAIDAMTGGRTDFDGMGGGQRNITNPDQKGEKEANTREAQESKDKKQGMVFPLPNGRFAAGPRQVYGAGRSYGGHAGIDLTEMPPFGSDPKIPVVAAISGTVLKEKYKGGQTYYSGMMIQGEDGYDQRYLHMEPTVKPGQKVQAGQVIGKLYDDADNTHLHFEVYKRGKGGHLNPAQIYPDLFKPGATGGGGEIQGSVTPPGATNPPDAPGTDSAANPSGAANVAKTIIPKASSAMSFEERYGSTRYTNDNFELATKKEEERRQQLQAMLPNMSNAMGPGAPQAGQQQGASAKQLQKITKDRNNARQLVQNRTQEMIQQVMAQVAKQNGMNQQMAQQASLQISQMMQQSMAQQNAAKNAPPQVVGGGGGGAAGGRGTELVGGIVKTTASALNSNLNPLKGLF

Other Proteins in cluster: phalp2_22754

Protein ID	Length (AA)	pI
Total (incl. this protein): 42	Avg length: 875,8	Avg pI: 9,74

8gQfh	725	9,40911
12e5g	951	10,01628
1SvsA	878	9,61767
1UKce	878	9,58324
1UPxn	936	9,82958
1VXYn	746	9,35535
1kubg	907	9,68259
1sg1J	1025	9,85265
1t6Ej	876	9,75763
1tBpm	868	9,75821
1tdnp	1013	9,89301
1yYDy	954	10,06185
1zxHu	1021	9,86071
26bbd	936	9,69509
27pb5	934	9,67569
2h3Mf	931	9,75621
3BUNg	982	10,04000
3xdTT	844	9,80617
4R93f	880	9,64352
4RGyd	1013	9,68297
4uoaU	695	9,49073
4upd8	881	9,61148
4ux0B	936	9,87419
4x7E6	727	9,72346
6O4lA	955	10,07707
7AkSc	868	9,85504
7PyJU	879	9,53225
7p5S1	1012	9,68297
8CxDj	982	10,04000
8Dnqa	855	9,79818
8F2fa	855	9,79818
8GEy8	662	9,55146
8GR1v	935	9,83712
8HqvF	867	9,86239
8LSV4	936	9,68265
8c04G	855	9,79818
8gzqH	935	9,83712
8xNJz	669	9,51961
dUmV	947	10,06476
r2y1	973	9,97521
A0A8S0I168	183	8,83128

Similar Clusters (pHMM search)

#	Cluster	# Members	Identity (%)	Alignment Length	E-value
1	phalp2_21079 8LRzV	133	33,1%	763	4.774E-78
2	phalp2_32545 1rZh9	26	26,1%	584	3.609E-22

Domains

Domains [InterPro]

No domain annotations available.

Taxonomy

	Name	Taxonomy ID	Lineage
Phage	Cyanophage P-RSM1 [NCBI]	536444	Kyanoviridae > Emcearvirus > Emcearvirus gerard
Host	Prochlorococcus marinus str. MIT 9303 [NCBI]	59922	Cyanobacteria > Prochlorales > Prochlorococcaceae > Prochlorococcus >

Coding sequence (CDS)

CDS Source ID

[NCBI]

CDS Source

HQ634175 [NCBI]

CDS location

range 45785 -> 48424
strand -

CDS

ATGGCAAAGGCAGCAGTACAAAAAGGTAGTAAGATTAATGTTTACAAGGTAGTAAGCATTAAAGAACCTGATGCGAGGATGAAGAAGAAAGATCCTAACGATTATGAAACAGCAAAAGGTCTTAATAAAACTACAGTAGCAATCAATAACTTAGGTGCCACTATCAATGGCATGAATGCGATGGTTGCTGATCTTAAGCAAGTATCATTAGATCGTCTTGAAGCAGCGAATAAAGATAAACCTAAAATGGATCCCAAGTATGGGACAACGAAGAAGGGTGCGGGTGGTATACTAGGTTCGATTGCAAAAGGATTTGTAAAGACTGGTGGTAGTTTCCTTGGTGGTTTGTTAAAACTACTAGGTGGGATGTTCAAGTTATTTGTAGTTCTTCCCATCTTAAATTGGTTATCCAAAGAAGAGAACCAACAAAAAGTTGCAGGTGCCCTAGAGGTAATGGCAAAGATTGGTAAGTTCATTTGGGAGTGGGCAAAGTTTGGAATCACAAATACGATAGATGGACTATATAAATTACTCAGCGATGATTCATCATGGATGGATCGTATTGTTGGATTTGGCCAGGCGTTCCTAGGATTTGCTTCTATCTTCATTGGCATGAAGGGGATAGCATGGTTACTAAATCCAATCAAAGTCGTTAAGGGTATTACAACAGCAATCAGAGCATTAATTAAGTTCGCAACTAACAGAGGGTTATCAAGTGTGACTGGTAGAAGAGGAAGAAAAGGAAGAGGATTTGCAGCAGGTGGTGCTCTTGCCACAACAATGACAGTAGCACCTATGGTAATGATGCCACAAATGGCAAAAGGTGGATGGATTAGTGGACCTATGTCAGGTTATCCTGTATCACTGGATGGTGGCAGGTCAACATCATTCATTGGTCATGGTACAGAGTATGTCTCACGGAAGGCAGGTGGACAAGCATTTGTCACCCCGTATGATACTCCTGCAACCCGTAGGAATCCTGGTCTGACTGCTATGAGACAATCAGAAGCAAAGAGAAAAGGTTTTGCTGAGGGTGGAGAAGTAAAAGAATCGTTGAATCTAACTGAAGATCAGTTCAGAAATCTTGCATTTGGTGTGAGTGGTGAAGCACAACGGGGCACTGATGATGAGTTTGGTGTTGCAGCAGCAATCTTGAATAGAGTTGCAGATCCTAGGTATCCTAATAGTATCATGCAAGTTCTCTCTGCTCCTGATCAGTATGAAGCATACCATAAGGGTAAGATGAAATTTGATGATCAATTACAAGACAGACTCTCATCTCAAAAAGGACAAGAAGGAATCATTGCTGCACTGAGAGAACTTAAAGGTAGAACTGACTTTAAAGGAACTGCCATGTACAAATACATGGGTGCAGATGATATTAAGTTCTCTAGAAAAGGAAACTTCTATCACTATCCAGAACAGAAAGCAAAATCCGATCCTCCTCCAGATACTATTCCAACTCATTACCTAAGATTCATTCAGAATCAAGAGGCATCAGACGATCAGCAAAGAGGGGAATCAAATGATCGTGCTGCGGTGGGTGTGATGGGCAAACTAAGTTCAGCACTCTCTGGTGTTACTAACGTGCTTAGTAACATTTTCTTGGGAGGTCCTGCTTCTGCTGCAGAAAATCCAGGTGTCGTAGATCCTCCTCCAAAAAAATTAGAATCAGAAGCAAACAATAAAGAAGGTGCAAATGCTAGTGCAGGTATTGAATCTGGTAGTTTAGGAGAGAAAGTATTCCCACTTCCTAAAGGTAGATTCCAAGCAACAGCAAGACAAGTGTTTGGTGCATCAAGAGGAGGAAGAAGTCATGCAGGTGTAGACTTAACTGAAGCACCTCCTTGGGGATCAGATCCAAAGATTCCTGTTGTTGCTGCTATTGCAGGATCAGTGTTAGCGGAAAGATATAAAGCAGGTCAAACATACTACTCAGGTATGATGATCAGAGGTCAAGATGGTCATGATCAGAGATACTTGCACATGGAACCTGCTGTCAAACCTGGGCAGGAAGTCAATGCAGGTGATCAGATTGGTAGACTTTATGATGATGGAGACAACAGTCACCTACACTTTGAGGTATACAAAAACGGTAAGGGTGGACCTCTAAATCCATCTCTCATCTATCCTAGTATGTTCAAAGCAGGAACTGCAGGTGGAGGACAGATGACTAATCCTACTGCATTCCAGAGCACTTCTAGTGTAACAAGTCCTGGTCAGAACAAACCTCCTCAAGCTGCCATTCAATCGATGGGTGATATGAGTAGGGAGGAGGATACGACTTTCTCTGGTCAAGATGGTATTATCAGTCAGTTCTCTGCTGAAAAGACAAGAGCAACAGAGTTGCAGAAGGCAACCGATGATAGAGATAAAGAAAGAGAAAACTTTAAAGCAGGAGTAGAGAATGCAGTAATGCAAGCATCACAACAGGTTCAACGATCTAACCAACAGAGTGCTGCTGCTATTCAACAGTCACAGCAAGGTGTTCAGCAAGCAGCACAATCGGGTGGTGGAGGTAAGGATGTAATCACTGGTGGTCTGCCTGGAATTGGTAATGTGAACATCAATGGTGTTATGAAAACTACAGCATATGCATTGAACTCTAATAATAACTTTATGCGAGGTATTCTTAGATGA

Gene Ontology

	Description	Category	Evidence (source)
GO:0004222	metalloendopeptidase activity	molecular function	None (UniProt)
GO:0016020	membrane	cellular component	None (UniProt)
GO:0031640	killing of cells of another organism	biological process	None (UniProt)
GO:0042742	defense response to bacterium	biological process	None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID

upi0002c132b2_model

Method AlphaFold3 (non-commercial)

Resolution -

Chain position -

Download PDB

Model Confidence

Very high
pLDDT > 90

High
90 > pLDDT > 70

Low
70 > pLDDT > 50

Very low
pLDDT < 50

The structures below correspond to the cluster representative (8gQfh) rather than this protein.

PDB ID

8gQfh

Method AlphaFoldv2

Resolution 61.53

Chain position -

Download PDB

Model Confidence

Very high
pLDDT > 90

High
90 > pLDDT > 70

Low
70 > pLDDT > 50

Very low
pLDDT < 50