Protein

Protein accession
A0AAE9K6P6 [UniProt]
Representative
5IWUp
Source
UniProt (cluster: phalp2_17543)
Protein name
Lysozyme
Lysin probability
99%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
MSNYKLSDKAAALLKEIEVLSLQPYDDSKGIKSAPTKYWTPEATIGYGHLILQNEWNQYKNGVTKEQAEALFLKDSEPMVVAINKLLKVSVTQQEFDALVILTFNIGLGAFIKSSVLKMGNKVGGSNYPTLEEAWLAFNIDQGKVSKGLVNRRKAEYNIYTKGIYQRW
Physico‐chemical
properties
protein length:168 AA
molecular weight:18897,5 Da
isoelectric point:9,10
hydropathy:-0,29
Representative Protein Details
Accession
5IWUp
Protein name
5IWUp
Sequence length
434 AA
Molecular weight
47751,50500 Da
Isoelectric point
5,15100
Sequence
VGNIYFISRDGNSWMELHNDGFVDIYGNLDISIRSEASVNIRADLDVNIEAGNSVNIKANGEGGIKLQADIANIDLSSANYYCTVSEDLNLLAKNVFVESEEESHFKNREFLVKAETNINMRGDNQLRFASDANISFTTGQNINFDGTRVDSNTGSGDLPSDADAANPATKIKSKVFLDIDFDQIGGATEENLESCVSRLPRHEPWPDHAVSPGSERISPNPEETGEEPPINASVGSVAEKAARPLPVVGSPKKGMSPGIYEPVSYEGDQPVYRNTGNQGDLIPAKDRVISPQGIEFIKKEEGFAPRKYPDGGKNRFSIGYGHQITGREPFDPEKGWTKQQATQVLTQDLEKFQAAVRKAVTAKVTQNQFDALTSFAFNVGIGALQKSTLVKKLNEGNYQEVPNEFMKWVFSEGKRNQGLIKRRRKEALLFTTP
Other Proteins in cluster: phalp2_17543
Total (incl. this protein): 3 Avg length: 240,3 Avg pI: 6,35
Protein ID Length (AA) pI
5IWUp 434 5,15100
A0A6J5L3F0 119 4,81411
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_37702
496b4
 7 34,9% 449 2.550E-56
2 phalp2_33749
10T6t
 3 23,7% 657 1.102E-26
3 phalp2_39498
5k0e3
 3 23,6% 512 6.855E-24
4 phalp2_13752
6LU4E
 2 30,4% 286 5.249E-23

Domains

Domains [InterPro]

No domain annotations available.

Taxonomy

  Name Taxonomy ID Lineage
Phage Pseudaeromonas phage vB_PpeM_ KLEP7
[NCBI] 		2928862 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
OM654377 [NCBI]
CDS location
range 6409 -> 6915
strand +
CDS
ATGAGCAATTATAAATTATCTGATAAAGCAGCTGCTTTGCTAAAAGAAATTGAAGTATTATCACTGCAACCATATGATGATTCTAAAGGAATTAAATCTGCACCAACTAAATATTGGACTCCAGAAGCAACCATTGGTTATGGTCATTTGATTTTACAAAATGAATGGAATCAATATAAGAACGGAGTTACAAAAGAACAAGCAGAAGCTTTATTCTTAAAAGATTCTGAACCCATGGTAGTAGCCATTAATAAATTGTTGAAAGTCTCTGTGACACAACAAGAGTTTGATGCATTGGTTATTCTTACTTTTAATATTGGTCTTGGTGCTTTTATTAAATCATCTGTTTTGAAAATGGGTAATAAAGTTGGCGGTTCAAATTATCCAACTCTAGAAGAGGCATGGCTTGCTTTTAATATAGACCAAGGTAAAGTTAGCAAAGGGTTAGTTAATCGCCGTAAAGCTGAATATAATATTTATACAAAAGGTATTTATCAGCGTTGGTGA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)
GO:0030430 host cell cytoplasm cellular component None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		RuleBase:RU003788

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (5IWUp) rather than this protein.
PDB ID
5IWUp
Method AlphaFoldv2
Resolution 80.94
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50