Protein

UniProt accession

Q5QBY1 [UniProt]

Protein name

Baseplate central spike protein

PhaLP type

endolysin

evidence: UniProt function annotation

probability: 99 % (predicted by ML model)

Protein sequence

MINMSDNLSWFVGVVEDRMDPLKQGRVRVRVWGMHPYEKVQGPVKGLRTEDLPWMSVLMPTSSASVSGIQTAMTGMVPGTQVYGHFLDKWKLNGLVLGTYGSASKQKANPNEGFSDPTGQYPLYLGNDAAALNRGGEVGYDATSNVIQDANTDVGINPDGLDLSQVKPDDNPNFTIENMLHRDEGLRLKVYWDTEGYPTIGIGHLITPQPIRDMNQINKILSNQIGREVKGNPGAISMDEASKLFQEDLKKVQNDIGRHSVVGPVYNKENRSRQMALENMAFQMGLGGLAKFKTMLGAMLVGDYKKAFDAARDSVWFNQTKGRASRVSMIILTGNMESYGIMAPKEREFNGRSYRMIQTFAAPTNSDPADPWTPEDTRILFKEPDSSYKGEYPYVQTMQTEGGHIQEFDNTPGQERYRLIHPTGSYEEVAPDGRKTSKTVADGYYMTQGDSNTYVGGNNKVNIGGDETYYNMANVRRQTDGSESIHIRGNETKTVEGDGTLIVKGNVTVIVEGNADITVKGDAKTLVEGNHDYTVNGNVKWSVNGNVDMTVAGNWSETMSTMSSIASGQYTIDGSRIDIG

Physico‐chemical properties

protein length:	580 AA
molecular weight:	63869,00000 Da
isoelectric point:	5,32686
aromaticity:	0,07931
hydropathy:	-0,57190

Domains

Domains [InterPro]

IPR010609

537–559

IPR010609 IPR009590 IPR023347

IPR023346

132–344

IPR023346

IPR001165

316–337

IPR001165 IPR002196

IPR046397

3–580

IPR046397

IPR052619

171–338

IPR052619

Protein sequence: Q5QBY1

1 580

Legend: Pfam SMART CDD TIGRFAM HAMAP SUPFAM PRINTS Gene3D PANTHER Other

Domains [InterPro]

InterPro ID	Start	End	Source	Name
IPR010609	537	559	Pfam	Gp5, C-terminal
IPR009590	33	173	Pfam	Protein Gp5, N-terminal OB-fold domain
IPR023347	174	342	Gene3D	Lysozyme domain superfamily
IPR023346	132	344	SUPFAM	Lysozyme-like domain superfamily
IPR001165	316	337	PRINTS	T4-type lysozyme
IPR046397	3	580	HAMAP	Pre-baseplate central spike protein Gp5
IPR002196	183	316	Pfam	Glycoside hydrolase, family 24
IPR052619	171	338	PANTHER	Bacteriophage lysozyme-like

Taxonomy

	Name	Taxonomy ID	Lineage
Phage	Escherichia phage JS98 [NCBI]	293178	Straboviridae > Dhakavirus > Dhakavirus JS98
Host	Escherichia coli [NCBI]	562	Bacteria > Proteobacteria > Gammaproteobacteria > Enterobacteriales > Enterobacteriaceae > Escherichia

Coding sequence (CDS)

Genbank protein accession

AAU29277.1 [NCBI]

Genbank nucleotide accession

EF469154 [NCBI]

CDS location

range 76876 -> 78618
strand +

CDS

ATGATTAACATGTCTGATAATTTAAGTTGGTTCGTCGGTGTAGTTGAAGACCGAATGGACCCACTCAAACAGGGCCGAGTACGCGTACGCGTCTGGGGTATGCATCCATATGAAAAAGTACAAGGTCCTGTAAAAGGCCTTCGTACAGAAGATTTACCATGGATGTCGGTATTAATGCCTACATCTTCTGCCTCTGTTTCAGGTATCCAAACCGCTATGACTGGTATGGTCCCAGGTACACAAGTTTATGGCCATTTTCTTGATAAGTGGAAATTAAACGGGCTTGTCCTCGGCACATATGGTTCAGCTTCAAAACAAAAGGCAAATCCAAACGAAGGTTTTAGTGACCCAACAGGACAGTATCCGCTTTATTTAGGTAATGATGCCGCTGCACTAAACCGAGGCGGTGAAGTTGGATATGATGCCACTTCTAACGTAATACAAGATGCAAACACTGATGTAGGTATTAATCCTGACGGTTTGGATTTAAGCCAAGTTAAGCCTGATGATAATCCTAATTTCACAATAGAAAACATGCTTCATCGTGATGAGGGTCTTCGTCTGAAGGTATATTGGGATACCGAAGGATATCCTACCATAGGTATAGGTCACCTTATTACTCCACAACCTATTAGAGATATGAATCAGATAAACAAAATATTATCTAATCAAATAGGTCGAGAAGTTAAAGGTAACCCTGGTGCAATATCAATGGACGAGGCTTCTAAGTTATTCCAAGAAGACCTTAAAAAAGTTCAAAACGATATAGGCCGGCATAGTGTTGTAGGTCCTGTTTACAATAAAGAAAACCGTTCAAGACAAATGGCTCTTGAAAACATGGCTTTCCAAATGGGTTTAGGTGGACTTGCTAAATTTAAAACGATGCTCGGTGCAATGTTAGTCGGAGATTATAAGAAAGCATTTGATGCCGCTCGTGATTCTGTATGGTTTAACCAAACTAAAGGCCGTGCCTCAAGGGTATCAATGATTATCCTTACAGGTAATATGGAATCATACGGTATTATGGCCCCTAAAGAAAGAGAATTTAATGGCCGTTCTTATAGGATGATTCAAACCTTTGCAGCCCCTACAAATTCTGACCCTGCCGACCCGTGGACTCCGGAAGATACAAGGATTCTTTTTAAAGAACCTGATTCTAGTTATAAAGGCGAATACCCATATGTCCAAACCATGCAAACTGAAGGCGGGCATATCCAAGAATTCGATAACACCCCAGGGCAAGAACGTTACCGATTAATCCACCCTACAGGTAGTTATGAAGAAGTCGCTCCTGACGGACGTAAAACTTCTAAGACGGTAGCCGACGGGTATTATATGACCCAAGGCGATTCTAATACTTATGTTGGTGGTAATAATAAAGTCAATATAGGTGGCGATGAAACCTATTATAATATGGCAAACGTTCGACGTCAAACTGACGGTTCTGAAAGCATCCATATTCGTGGTAATGAAACCAAAACGGTAGAAGGCGACGGGACCCTTATTGTTAAAGGAAATGTTACGGTTATTGTTGAAGGCAATGCTGATATAACTGTTAAAGGTGATGCAAAAACCTTAGTCGAAGGCAACCATGATTATACAGTAAATGGAAATGTTAAGTGGTCGGTAAACGGAAACGTCGATATGACTGTTGCCGGTAATTGGTCTGAAACTATGTCGACTATGAGTTCTATTGCGTCCGGTCAATATACTATTGATGGTTCGAGGATTGACATTGGCTAA

Gene Ontology

	Description	Category	Evidence (source)
GO:0003796	lysozyme activity	Molecular function	Inferred from Electronic Annotation (UniProt)
GO:0009253	peptidoglycan catabolic process	Biological process	Inferred from Electronic Annotation (InterPro)
GO:0016998	cell wall macromolecule catabolic process	Biological process	Inferred from Electronic Annotation (InterPro)
GO:0031640	killing of cells of another organism	Biological process	Inferred from Electronic Annotation (UniProt)
GO:0042742	defense response to bacterium	Biological process	Inferred from Electronic Annotation (UniProt)
GO:0098003	viral tail assembly	Biological process	Inferred from Electronic Annotation (UniProt)
GO:0098025	virus tail, baseplate	Cellular component	Inferred from Electronic Annotation (UniProt)
GO:0098932	symbiont entry into host cell via disruption of host cell wall peptidoglycan	Biological process	Inferred from Electronic Annotation (UniProt)
GO:0098994	symbiont entry into host cell via disruption of host cell envelope	Biological process	Inferred from Electronic Annotation (UniProt)

Enzymatic activity

EC Number	Entry Name	Reaction Catalyzed	Classification	Evidence	Source
3.2.1.17	lysozyme aka muramidase	D-glucosamine residues in chitodextrins	Hydrolases Glycosylases Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds	match to sequence model evidence used in automatic assertion ECO:0000256	HAMAP-Rule:MF_04151

Tertiary structure

No tertiary structures available.