Protein

UniProt accession
Q4ZE57 [UniProt]
Protein name
N-acetylmuramoyl-L-alanine amidase
PhaLP type
endolysin

evidence: GO annotation

probability: 99 % (predicted by ML model)

Protein sequence
MKSQQQAKEWIYNHEGAGVDFDGAYGFQCMDLAVAYVYYITDGKVRMWGNAKDAINNDFKGLATVYKNTPSFKPQLGDVAVYTNSQYGHIQCVISGNLDYYTCLEQNWLNGGFDKWEKATIRTHYYDGVTHFIRPKFSGSKSHELETSKVNTFGNWKQNQYGTYYRNENATFTCGFLPIFARVSSPKLSEPNGYWFQPNGYTPYDEICLSDGYVWIGYNWQGTRYYLPVRQWNGKTGNSYSVGIPWGVFS
Physico‐chemical
properties
protein length:250 AA
molecular weight:28742,00000 Da
isoelectric point:7,58968
aromaticity:0,18400
hydropathy:-0,59800

Domains

Domains [InterPro]
IPR003646
164–229
IPR003646 IPR007921
IPR007921
22–107
IPR007921
IPR038765
20–139
IPR038765
Protein sequence: Q4ZE57
1 250
Legend: Pfam SMART CDD TIGRFAM HAMAP SUPFAM PRINTS Gene3D PANTHER Other

Taxonomy

  Name Taxonomy ID Lineage
Phage Staphylococcus phage 66
[NCBI] 		320832 Rountreeviridae > Rosenblumvirus > Rosenblumvirus rv66
Host Staphylococcus aureus
[NCBI] 		1280 Bacteria > Firmicutes > Bacilli > Bacillales > Staphylococcaceae > Staphylococcus

Coding sequence (CDS)

Coding sequence (CDS)
Genbank protein accession
AAX90660.1 [NCBI]
Genbank nucleotide accession
AY954949 [NCBI]
CDS location
range 5814 -> 6566
strand +
CDS
ATGAAATCACAACAACAAGCAAAAGAATGGATATATAATCATGAGGGTGCAGGTGTTGATTTTGATGGTGCATATGGATTTCAATGTATGGACTTAGCTGTTGCTTATGTATATTACATTACAGACGGTAAAGTTCGTATGTGGGGCAACGCAAAAGACGCCATTAACAACGACTTTAAAGGTTTAGCAACGGTGTATAAAAATACACCGAGCTTTAAACCTCAATTAGGTGATGTTGCTGTTTATACTAATTCTCAATATGGTCATATTCAATGTGTGATAAGTGGAAATTTAGATTATTATACATGTTTAGAGCAAAACTGGTTAAATGGTGGTTTTGACAAGTGGGAAAAAGCAACTATTAGAACACATTATTATGACGGTGTAACACACTTTATTCGTCCAAAATTTTCAGGAAGTAAAAGCCACGAATTAGAAACATCAAAAGTCAATACATTTGGAAATTGGAAACAAAATCAATATGGTACGTATTACAGAAATGAGAATGCAACATTTACATGTGGATTTTTACCAATATTTGCACGTGTCAGCAGTCCAAAATTATCAGAACCTAATGGCTATTGGTTCCAACCAAATGGCTATACACCATATGACGAAATTTGTTTATCAGATGGTTACGTATGGATTGGTTATAATTGGCAAGGCACACGTTATTATTTACCAGTACGTCAATGGAATGGTAAAACAGGTAATAGTTACAGTGTTGGAATTCCTTGGGGGGTGTTCTCATAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell Biological process Inferred from Electronic Annotation (InterPro)
GO:0003824 catalytic activity Molecular function Inferred from Electronic Annotation (InterPro)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.5.1.28 N-acetylmuramoyl-L-alanine amidase residues in certain cell-wall glycopeptides
Hydrolases
Acting on carbon-nitrogen bonds, other than peptide bonds
In linear amides
 match to sequence model evidence used in automatic assertion
ECO:0000256 		ARBA:ARBA00001561

Tertiary structure

No tertiary structures available.