Protein

UniProt accession
Q4ZCK1 [UniProt]
Protein name
N-acetylmuramoyl-L-alanine amidase
PhaLP type
endolysin

evidence: GO annotation

probability: 99 % (predicted by ML model)

Protein sequence
MLITKNQAEKWFDNSLGKQFNPDLFYGFQCYDYANMFFMIATGERLQGLYAYNIPFDNKARIEKYGQIIKNYDSFLPQKLDIVVFPSKYGGGAGHVEIVESANLNTFTSFGQNWNGKGWTNGVAQPGWGPETVTRHVHYYDDPMYFIRLNFPDKVSVGDKAKSVIKQATAKKQAVIKPKKIMLVAGHGYNDPGAVGNGTNERDFIRKYITPNIAKYLRHAGHEVALYGGSSQSQDMYQDTAYGVNVGNNKDYGLYWVKSHGYDIVLEIHLDAAGESASGGHVIISSQFNADTIDKSIQDVIKNNLGQIRGVTPRNDLLNVNVSAEININYRLSELGFITNKNDMDWIKKNYDLYSKLIAGAIHGKPIGGLVAGNVKTSAKNQKNPPVPAGYTLDKNNVPYKKETGYYTVANVKGNNVRDGYSTNSRITGVLPNNATIKYDGAYCINGYRWITYIANSGQRRYIATGEVDKAGNRISSFGKFSTI
Physico‐chemical
properties
protein length:484 AA
molecular weight:53830,00000 Da
isoelectric point:9,24246
aromaticity:0,11983
hydropathy:-0,47293

Domains

Domains [InterPro]
IPR038765
22–158
IPR038765 IPR003646 IPR002508
IPR007921
5–148
IPR007921 IPR002508 IPR003646
IPR050695
32–364
IPR050695
IPR007921
26–113
IPR007921 IPR002508
Protein sequence: Q4ZCK1
1 484
Legend: Pfam SMART CDD TIGRFAM HAMAP SUPFAM PRINTS Gene3D PANTHER Other

Taxonomy

  Name Taxonomy ID Lineage
Phage Triavirus tv47
[NCBI] 		320839 Triavirus >
Host Staphylococcus aureus
[NCBI] 		1280 Bacteria > Firmicutes > Bacilli > Bacillales > Staphylococcaceae > Staphylococcus

Coding sequence (CDS)

Coding sequence (CDS)
Genbank protein accession
AAX91198.1 [NCBI]
Genbank nucleotide accession
AY954957 [NCBI]
CDS location
range 20419 -> 21873
strand +
CDS
ATGTTGATAACAAAAAACCAAGCAGAAAAATGGTTTGATAATTCATTAGGGAAGCAGTTCAATCCTGATTTGTTTTATGGATTTCAGTGTTACGATTACGCAAATATGTTTTTTATGATAGCAACAGGCGAAAGGTTACAAGGTTTATACGCTTATAATATTCCATTTGATAATAAAGCAAGGATTGAAAAATACGGGCAAATAATTAAAAACTATGATAGCTTTTTACCGCAAAAGTTGGACATTGTCGTTTTCCCGTCAAAGTATGGTGGCGGAGCTGGACATGTTGAAATTGTTGAGAGCGCTAATCTAAACACTTTCACATCGTTTGGCCAAAATTGGAATGGTAAAGGTTGGACAAATGGCGTTGCGCAACCTGGTTGGGGTCCCGAAACCGTTACAAGACATGTTCATTATTACGATGACCCAATGTATTTTATTAGATTAAATTTCCCAGATAAAGTAAGTGTTGGAGATAAAGCTAAAAGCGTTATTAAGCAAGCAACTGCCAAAAAGCAAGCAGTAATTAAACCTAAAAAAATTATGCTTGTAGCCGGTCATGGTTATAACGATCCTGGAGCAGTCGGAAACGGAACAAATGAACGTGATTTTATCCGTAAATATATAACACCAAATATCGCTAAGTATTTAAGACATGCAGGTCACGAAGTTGCATTATATGGTGGCTCAAGTCAATCACAAGATATGTATCAAGATACTGCTTACGGTGTTAATGTAGGAAATAATAAAGATTATGGCTTATATTGGGTTAAATCACATGGGTATGACATTGTTCTAGAGATTCATTTAGACGCAGCAGGAGAAAGTGCAAGTGGTGGGCATGTTATTATTTCAAGTCAATTCAATGCAGATACTATTGATAAAAGTATACAAGATGTTATTAAAAATAACTTAGGACAAATAAGAGGTGTAACACCTCGTAATGATTTACTAAACGTTAATGTATCAGCAGAAATAAATATAAACTATCGTTTATCTGAATTAGGTTTTATTACTAATAAAAATGATATGGATTGGATTAAGAAAAACTATGACTTGTATTCTAAATTAATAGCCGGTGCGATTCATGGTAAGCCTATAGGTGGTTTGGTAGCTGGTAATGTTAAAACATCAGCTAAAAACCAAAAAAATCCACCAGTGCCAGCAGGTTATACACTTGATAAAAACAATGTACCGTATAAAAAAGAGACTGGTTATTACACAGTTGCCAATGTTAAAGGTAATAACGTAAGGGACGGCTATTCAACTAATTCAAGAATTACAGGTGTATTACCTAATAACGCAACAATTAAATATGACGGCGCATATTGCATCAATGGCTATAGATGGATTACTTATATTGCTAATAGTGGACAACGTCGTTATATAGCGACAGGAGAGGTAGACAAGGCAGGTAATAGAATAAGTAGTTTTGGTAAGTTTAGCACGATTTAG

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell Biological process Inferred from Electronic Annotation (InterPro)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity Molecular function Inferred from Electronic Annotation (UniProt)
GO:0009253 peptidoglycan catabolic process Biological process Inferred from Electronic Annotation (InterPro)
GO:0071555 cell wall organization Biological process Inferred from Electronic Annotation (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.5.1.28 N-acetylmuramoyl-L-alanine amidase residues in certain cell-wall glycopeptides
Hydrolases
Acting on carbon-nitrogen bonds, other than peptide bonds
In linear amides
 match to sequence model evidence used in automatic assertion
ECO:0000256 		ARBA:ARBA00001561

Tertiary structure

No tertiary structures available.