Protein

UniProt accession
Q1A072 [UniProt]
Protein name
N-acetylmuramoyl-L-alanine amidase domain-containing protein
PhaLP type
endolysin

evidence: GO annotation

probability: 99 % (predicted by ML model)

Protein sequence
MSFIRSKFAPRALLTVDQWIAIFAAVADELDMPDKRGAVICAAMCAFQEAGADLEDGNGRQIWIPGNMADPCYADDPDAYPHDSEGDDGQSTGPFQQQMNEPGKAPWGWGGNYGDCAGTRKRMDPWDSTRMFFGWPGSGLKAKGYDASSAQAANDSIQRVQGSGVPWAYAQWWGLANAAYDRYLGNPIPAPPSPGGGSGPAPALVPNPAWRGDPLFLPQVLRAFGVNVSTYTDADGIRWDQRGHGDFGKISWVLWHHTGSVNETDEGIAHHPALGLAANMLIHPDGHVVLTGSGIAWHGGIGIYPGIPEDGINQVSIGIECSYGPDENGQYTLPWPTAQMNAMIAVGAAISWFLGDTLPVDHQISHKAWAGADNPLGINKQGKPDPGNLDMNWFRAQIAARTALGPTTGGDDWMADPTALELLRDIHRETVTQKSPSRSFMAEDGKLIDSPLGIEWNTDGNAWTLVLTEGYWNDVPLAIAVVEDIAANGVRQTSWAGSADKDSAVKFNQWLRDFGQAYCQGLVRRKAQWNALVAAVASLSAAQAAGATTAVKAAPRKRAAKKAPAPKDAE
Physico‐chemical
properties
protein length:570 AA
molecular weight:61017,00000 Da
isoelectric point:5,03118
aromaticity:0,09298
hydropathy:-0,33912

Domains

Domains [InterPro]
IPR002502
248–387
IPR002502
IPR036505
237–400
IPR036505
IPR036505
233–403
IPR036505
Protein sequence: Q1A072
1 570
Legend: Pfam SMART CDD TIGRFAM HAMAP SUPFAM PRINTS Gene3D PANTHER Other

Taxonomy

  Name Taxonomy ID Lineage
Phage Mycobacterium phage Cooper
[NCBI] 		373406 Coopervirus > Coopervirus cooper
Host Mycobacterium
[NCBI] 		1763 Bacteria > Actinobacteria > Actinobacteria > Corynebacteriales > Mycobacteriaceae >
Host Mycobacterium smegmatis
[NCBI] 		1772 Bacteria > Actinobacteria > Actinobacteria > Corynebacteriales > Mycobacteriaceae > Mycobacterium

Coding sequence (CDS)

Coding sequence (CDS)
Genbank protein accession
ABD58161.1 [NCBI]
Genbank nucleotide accession
DQ398044 [NCBI]
CDS location
range 39744 -> 41456
strand +
CDS
GTGAGCTTCATCCGGTCGAAATTCGCACCCCGTGCCCTGCTGACCGTCGACCAGTGGATCGCCATTTTCGCCGCCGTAGCCGACGAGCTGGACATGCCGGACAAGCGCGGCGCGGTGATCTGCGCCGCCATGTGCGCCTTCCAGGAGGCCGGTGCCGATCTGGAGGACGGCAACGGGCGGCAAATCTGGATCCCTGGCAACATGGCCGACCCGTGCTACGCCGACGACCCCGACGCCTACCCGCACGACAGCGAAGGCGACGACGGGCAGTCCACCGGCCCGTTCCAGCAGCAGATGAACGAGCCGGGGAAAGCGCCCTGGGGCTGGGGCGGCAACTATGGCGACTGCGCCGGTACCCGCAAGCGCATGGACCCGTGGGACAGCACGCGCATGTTCTTCGGCTGGCCGGGCAGCGGGCTCAAGGCCAAGGGCTACGACGCCAGCAGCGCCCAGGCAGCCAACGACAGCATTCAGCGGGTGCAGGGCAGCGGCGTGCCGTGGGCTTATGCGCAGTGGTGGGGCTTGGCGAACGCCGCCTATGACCGGTACCTGGGCAACCCGATCCCGGCACCGCCCAGCCCCGGCGGTGGCAGTGGCCCAGCTCCGGCGCTGGTGCCGAACCCGGCCTGGCGTGGCGACCCGCTGTTCCTGCCCCAGGTGCTGCGGGCCTTCGGCGTGAACGTGAGCACCTACACCGACGCCGACGGCATCCGGTGGGACCAGCGCGGGCATGGCGACTTCGGGAAAATCTCGTGGGTGCTATGGCACCACACGGGCAGCGTCAACGAGACGGACGAGGGCATCGCGCATCACCCGGCGCTCGGGCTGGCCGCGAACATGCTCATCCACCCCGACGGGCACGTGGTGCTCACCGGCAGCGGCATCGCCTGGCACGGCGGCATCGGCATCTATCCCGGCATCCCCGAGGACGGCATCAACCAGGTCAGCATCGGTATCGAGTGCAGCTACGGGCCGGATGAGAACGGCCAGTACACCCTGCCCTGGCCTACCGCGCAGATGAACGCCATGATCGCCGTGGGCGCAGCCATCAGCTGGTTCCTGGGCGACACGCTGCCCGTCGACCACCAGATCAGTCACAAGGCGTGGGCGGGCGCAGATAACCCGCTCGGCATCAATAAGCAGGGCAAGCCGGACCCCGGCAACCTGGACATGAACTGGTTCCGTGCGCAGATCGCAGCGCGCACGGCCCTTGGCCCCACAACCGGAGGAGATGACTGGATGGCCGACCCCACCGCGCTGGAACTGCTGCGCGACATTCACCGCGAGACCGTGACGCAGAAGTCCCCGAGCCGGTCGTTCATGGCCGAGGACGGCAAGCTGATCGACAGCCCGCTGGGCATCGAGTGGAACACCGACGGCAATGCCTGGACCCTGGTACTCACCGAGGGGTATTGGAACGACGTGCCGCTGGCCATCGCCGTGGTCGAGGACATCGCCGCCAACGGCGTGCGGCAGACCAGCTGGGCGGGCAGCGCCGACAAGGACAGTGCCGTCAAGTTCAACCAGTGGCTCCGCGACTTCGGCCAGGCGTATTGCCAGGGCCTGGTTCGGCGTAAGGCGCAGTGGAACGCTCTGGTGGCTGCCGTGGCCAGCCTGAGCGCTGCGCAGGCGGCAGGGGCCACCACAGCCGTGAAAGCGGCACCACGCAAGCGCGCCGCGAAGAAGGCCCCCGCGCCCAAGGACGCAGAATGA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell Biological process Inferred from Electronic Annotation (InterPro)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity Molecular function Inferred from Electronic Annotation (UniProt)
GO:0009253 peptidoglycan catabolic process Biological process Inferred from Electronic Annotation (InterPro)
GO:0042742 defense response to bacterium Biological process Inferred from Electronic Annotation (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available.