Protein

UniProt accession

Q19Y11 [UniProt]

Protein name

N-acetylmuramoyl-L-alanine amidase domain-containing protein

PhaLP type

endolysin

evidence: GO annotation

probability: 99 % (predicted by ML model)

Protein sequence

MDVGTLRRVMSPTDVSDAKLAEYLPHFVEAMNAAQINNQRRFAAWCSQIGHESGGLKYMAEIKTSDPNWSWDRTRYRGRGPIQLTWQSNYRKFGVWCKKMGYVSDSELFVNQPELVEQPRWGFLAAAWYWMEGGPKPGQINGFADAGNILAVSRCVNGWVESQLPNGWTDRQARWNRVLAIPFDGSYTPATTPEPGFTGDPWWLADVLRAEGLRVFEVDGWQNRGQGDQGTFWGVMFHHTGSPNETPEGIAFHPTLGLAAHILIKPNGDVWVCGIGKANHAGRGDYPGLPTNNANPVMIGVEVAILPRKDAPHREGWPDVQYDATVKVHAAILRKLGLRADRCISHREWGERAQGKWDPGAIDMNIHRRDVQARIDSFNPVGGDGGWLMALSDAEQRELLDKVRQLWGASFNPVGDTAIFGNPDPNHKIPNKDRLTYTDGNVWDSHVADLAKAGVDWAIEIVVRTAAGRGPLGDVDWVKAYAVSVLESIPNKEEVLGNWDPS

Physico‐chemical properties

protein length:	502 AA
molecular weight:	55845,00000 Da
isoelectric point:	5,93288
aromaticity:	0,10159
hydropathy:	-0,46275

Domains

Domains [InterPro]

IPR002502

221–360

IPR002502 IPR000726

IPR036505

215–373

IPR036505 IPR023346

IPR002502

234–360

IPR002502

IPR036505

215–377

IPR036505

Protein sequence: Q19Y11

1 502

Legend: Pfam SMART CDD TIGRFAM HAMAP SUPFAM PRINTS Gene3D PANTHER Other

Domains [InterPro]

InterPro ID	Start	End	Source	Name
IPR002502	221	360	CDD	N-acetylmuramoyl-L-alanine amidase domain
IPR036505	215	373	Gene3D	N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily
IPR002502	234	360	CDD	N-acetylmuramoyl-L-alanine amidase domain
IPR000726	68	137	Pfam	Glycoside hydrolase, family 19, catalytic
IPR036505	215	377	Gene3D	N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily
IPR023346	16	181	SUPFAM	Lysozyme-like domain superfamily

Taxonomy

	Name	Taxonomy ID	Lineage
Phage	Mycobacterium phage Wildcat [NCBI]	373415	Vilmaviridae > Wildcatvirus > Mycobacterium virus Wildcat
Host	Mycobacterium [NCBI]	1763	Bacteria > Actinobacteria > Actinobacteria > Corynebacteriales > Mycobacteriaceae >
Host	Corynebacteriales [NCBI]	85007	Bacteria > Actinobacteria > Actinobacteria >

Coding sequence (CDS)

Genbank protein accession

ABE67654.1 [NCBI]

Genbank nucleotide accession

DQ398052 [NCBI]

CDS location

range 36288 -> 37796
strand +

CDS

ATGGATGTAGGGACTTTGCGTCGTGTCATGTCTCCTACTGATGTTTCTGACGCGAAGCTGGCTGAGTATCTTCCGCATTTCGTGGAGGCGATGAACGCTGCCCAGATCAATAATCAGCGTCGCTTTGCTGCGTGGTGTTCTCAGATTGGGCACGAGTCGGGTGGCCTCAAGTATATGGCTGAGATCAAGACATCCGATCCTAACTGGAGTTGGGACCGTACTCGTTACCGTGGCCGTGGACCTATTCAGTTGACGTGGCAGAGCAATTACCGCAAGTTCGGTGTGTGGTGCAAGAAGATGGGCTACGTGTCGGACAGTGAGCTGTTTGTGAATCAGCCCGAGCTTGTGGAGCAGCCTCGTTGGGGTTTCCTTGCGGCGGCGTGGTATTGGATGGAGGGTGGCCCAAAGCCGGGGCAGATCAACGGATTCGCGGACGCTGGGAATATTCTGGCTGTGTCGCGTTGTGTGAATGGTTGGGTGGAGTCGCAGCTTCCGAATGGCTGGACGGATCGTCAGGCTCGATGGAATCGCGTGCTGGCCATCCCGTTTGATGGGTCCTACACTCCTGCCACTACTCCTGAGCCTGGGTTCACTGGTGACCCGTGGTGGCTGGCTGATGTGTTGCGCGCGGAGGGTCTTCGCGTGTTCGAGGTGGATGGTTGGCAGAACCGTGGCCAGGGCGACCAGGGAACTTTCTGGGGGGTCATGTTCCACCACACTGGTTCTCCGAACGAGACTCCGGAGGGCATTGCCTTCCACCCGACTTTGGGTTTGGCTGCCCACATTCTGATCAAGCCGAACGGCGACGTGTGGGTGTGTGGTATCGGTAAGGCGAACCACGCTGGTCGTGGCGATTATCCTGGCCTGCCTACAAACAACGCGAACCCGGTGATGATCGGCGTCGAGGTGGCGATCCTGCCTCGCAAGGATGCTCCGCACCGTGAGGGCTGGCCAGATGTGCAGTACGACGCAACTGTGAAGGTGCATGCGGCTATTCTCCGCAAGCTGGGGTTGCGTGCCGATAGGTGTATCTCGCACCGTGAGTGGGGCGAGCGCGCGCAGGGCAAGTGGGACCCTGGCGCTATTGACATGAACATTCATCGTCGGGACGTGCAGGCCCGTATCGATTCGTTTAATCCCGTTGGGGGAGATGGAGGTTGGCTGATGGCTCTCTCGGATGCAGAGCAGCGTGAGCTTCTGGACAAGGTTCGTCAGCTATGGGGCGCGTCGTTTAATCCCGTTGGGGACACTGCGATCTTCGGTAATCCTGACCCGAACCACAAGATCCCGAACAAGGATCGCTTGACCTACACCGATGGCAATGTGTGGGATTCGCACGTGGCGGATCTGGCGAAGGCTGGTGTGGATTGGGCCATCGAGATTGTGGTTCGCACCGCAGCGGGTCGTGGGCCTCTTGGTGATGTGGATTGGGTGAAGGCATACGCCGTGAGCGTGCTGGAGTCGATCCCGAATAAGGAAGAGGTGCTGGGGAATTGGGACCCATCGTGA

Gene Ontology

	Description	Category	Evidence (source)
GO:0001897	symbiont-mediated cytolysis of host cell	Biological process	Inferred from Electronic Annotation (InterPro)
GO:0004568	chitinase activity	Molecular function	Inferred from Electronic Annotation (TreeGrafter)
GO:0006032	chitin catabolic process	Biological process	Inferred from Electronic Annotation (TreeGrafter)
GO:0008745	N-acetylmuramoyl-L-alanine amidase activity	Molecular function	Inferred from Electronic Annotation (UniProt)
GO:0009253	peptidoglycan catabolic process	Biological process	Inferred from Electronic Annotation (InterPro)
GO:0016998	cell wall macromolecule catabolic process	Biological process	Inferred from Electronic Annotation (InterPro)
GO:0042742	defense response to bacterium	Biological process	Inferred from Electronic Annotation (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available.