Protein

UniProt accession
Q19X58 [UniProt]
Protein name
N-acetylmuramoyl-L-alanine amidase
PhaLP type
endolysin

evidence: GO annotation

probability: 99 % (predicted by ML model)

Protein sequence
MPAYTQDGIAIGIIAEGRRSRSGEGQLDHPVISEKGIVIALAVALVETNLKMYANRSDPESLNFPHDAVGSDANSVGVFQQRAPWWGTVADRMDVARSAAMFYNSLYRQRVGGADYNTDRVSPGTWGQMVQQSAFPDRYDKRMAEARQIYDRLKDRVVGGAPTPPPITAPDPNWRGDPVWLKEVLEAAGLVCHVYDGAYNRGHGDFGEIWGVVAHHTGSFGETPKGIAQHPSLGLASQLYLGRNGEYTLCGVGIAWHAGQGSYPGLPTNDANRLTIGIEAANDGGGSPPGKRDAWSDVQYNAYVRGVAAILRKLGRDSSRVIGHKEWAGTAQGKWDPGGIDMNTFRADVARVMGELGTSTDPVLELLAMPTNQEKLDFIYNEESKKFASRSIYRTPGEGLIDTRAGFVLNVDAMAHQELVDRLAIQYHDSDAIGRIARVAAGQGADPNDTWAKEHALMVLQKIPEEVLKAWQEKNR
Physico‐chemical
properties
protein length:476 AA
molecular weight:51891,00000 Da
isoelectric point:5,87729
aromaticity:0,08193
hydropathy:-0,42794

Domains

Domains [InterPro]
IPR002502
196–338
IPR002502
IPR002502
211–339
IPR002502
IPR002502
208–338
IPR002502
IPR051206
254–377
IPR051206
IPR036505
195–353
IPR036505
IPR036505
198–352
IPR036505
Protein sequence: Q19X58
1 476
Legend: Pfam SMART CDD TIGRFAM HAMAP SUPFAM PRINTS Gene3D PANTHER Other

Taxonomy

  Name Taxonomy ID Lineage
Phage Mycobacterium phage Catera
[NCBI] 		373404 Bixzunavirus > Bixzunavirus Bxz1
Host Mycobacterium
[NCBI] 		1763 Bacteria > Actinobacteria > Actinobacteria > Corynebacteriales > Mycobacteriaceae >
Host Mycobacterium smegmatis
[NCBI] 		1772 Bacteria > Actinobacteria > Actinobacteria > Corynebacteriales > Mycobacteriaceae > Mycobacterium

Coding sequence (CDS)

Coding sequence (CDS)
Genbank protein accession
ABE67955.1 [NCBI]
Genbank nucleotide accession
DQ398053 [NCBI]
CDS location
range 141172 -> 142602
strand +
CDS
GTGCCCGCATACACACAGGACGGCATCGCCATCGGCATCATCGCCGAGGGGCGACGTTCGCGGTCTGGAGAAGGCCAGCTTGATCACCCGGTGATCAGCGAGAAGGGCATTGTCATCGCGCTCGCCGTCGCCCTGGTCGAGACCAACCTCAAGATGTACGCCAATCGGTCGGACCCGGAGAGCCTCAATTTCCCGCACGACGCGGTCGGCAGCGACGCCAACAGCGTCGGCGTCTTCCAGCAGCGCGCTCCCTGGTGGGGCACGGTCGCCGATCGCATGGACGTCGCGCGCAGCGCGGCGATGTTCTACAACAGCCTGTATCGCCAGCGCGTCGGCGGCGCCGACTACAACACCGATCGGGTCTCTCCCGGTACCTGGGGCCAGATGGTCCAGCAGTCCGCCTTTCCGGATCGCTACGACAAACGTATGGCCGAGGCCCGGCAGATCTATGACCGGCTCAAGGACCGAGTGGTCGGCGGTGCTCCTACTCCGCCGCCGATCACCGCCCCGGACCCGAACTGGCGCGGCGACCCCGTCTGGCTCAAGGAGGTCCTCGAAGCCGCAGGCCTGGTTTGCCACGTCTACGACGGCGCCTACAACCGGGGCCACGGCGACTTCGGCGAGATCTGGGGCGTGGTGGCTCACCACACCGGCAGCTTCGGCGAGACACCCAAGGGCATCGCTCAGCACCCCAGTCTGGGCCTGGCCAGCCAGCTCTATCTGGGCCGTAACGGCGAGTACACCCTGTGTGGGGTCGGTATCGCCTGGCACGCCGGGCAGGGCAGCTATCCCGGCCTGCCGACCAACGACGCCAACCGGCTCACCATCGGCATCGAAGCAGCCAATGACGGGGGCGGCTCTCCTCCTGGCAAACGCGATGCCTGGAGCGATGTGCAGTACAACGCCTATGTCCGTGGCGTTGCCGCCATTTTGCGCAAACTCGGTCGGGATTCCAGCCGGGTGATCGGCCATAAGGAGTGGGCCGGTACCGCGCAGGGCAAGTGGGACCCCGGCGGCATCGACATGAACACCTTCCGCGCCGACGTGGCCCGTGTGATGGGCGAACTTGGCACCTCGACCGACCCAGTATTGGAGCTACTCGCCATGCCTACCAACCAGGAGAAGCTGGACTTCATCTACAACGAGGAGTCGAAGAAGTTCGCCTCGCGTTCGATCTACCGCACTCCAGGTGAGGGCCTGATCGACACTCGGGCCGGATTCGTCCTCAACGTCGACGCCATGGCTCATCAAGAGCTCGTCGACCGGCTGGCCATCCAGTACCACGACAGCGACGCCATCGGGCGCATCGCGCGGGTGGCCGCTGGCCAGGGCGCCGACCCCAACGACACCTGGGCAAAGGAGCACGCGCTCATGGTGCTGCAGAAGATCCCCGAAGAGGTCCTCAAGGCCTGGCAGGAGAAGAACCGATGA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell Biological process Inferred from Electronic Annotation (InterPro)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity Molecular function Inferred from Electronic Annotation (UniProt)
GO:0009253 peptidoglycan catabolic process Biological process Inferred from Electronic Annotation (InterPro)
GO:0009254 peptidoglycan turnover Biological process Inferred from Electronic Annotation (TreeGrafter)
GO:0042742 defense response to bacterium Biological process Inferred from Electronic Annotation (UniProt)
GO:0071555 cell wall organization Biological process Inferred from Electronic Annotation (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.5.1.28 N-acetylmuramoyl-L-alanine amidase residues in certain cell-wall glycopeptides
Hydrolases
Acting on carbon-nitrogen bonds, other than peptide bonds
In linear amides
 match to sequence model evidence used in automatic assertion
ECO:0000256 		ARBA:ARBA00001561

Tertiary structure

No tertiary structures available.