Protein

UniProt accession
P27380 [UniProt]
Protein name
Transglycosylase
PhaLP type
VAL

evidence: GO annotation

probability: 99 % (predicted by ML model)

Protein sequence
MSGALQWWETIGAASAQYNLDPRLVAGVVQTESSGNPRTTSGVGAMGLMQLMPATAKSLGVTNAYDPTQNIYGGAALLRENLDRYGDVNTALLAYHGGTNQANWGAKTKSYPGKVMKNINLLFGNSGPVVTPAAGIAPVSGAQEMTAVNISDYTAPDLTGLTMGAGSPDFTGGASGSWGEENIPWYRVDKHVANAAGSAYDAVTDAVSAPVEAAGNYALRGVVIIAAVAIVVVGLYFLFQDEINSAAMKMIPAGKAAGAAAKALA
Physico‐chemical
properties
protein length:265 AA
molecular weight:27074,00000 Da
isoelectric point:5,12838
aromaticity:0,07547
hydropathy:0,10981

Domains

Domains [InterPro]
IPR023346
5–121
IPR023346
IPR000189
28–56
IPR000189
IPR008258
10–113
IPR008258
Protein sequence: P27380
1 265
Legend: Pfam SMART CDD TIGRFAM HAMAP SUPFAM PRINTS Gene3D PANTHER Other

Taxonomy

  Name Taxonomy ID Lineage
Phage Enterobacteria phage PRD1 (Bacteriophage PRD1)
[NCBI] 		10658 Kalamavirales > Tectiviridae > Alphatectivirus > Alphatectivirus PRD1
Host Pseudomonas aeruginosa
[NCBI] 		287 Bacteria > Proteobacteria > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas
Host Pseudomonas fluorescens
[NCBI] 		294 Bacteria > Proteobacteria > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas
Host Pseudomonas putida
[NCBI] 		303 Bacteria > Proteobacteria > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas
Host Acinetobacter calcoaceticus
[NCBI] 		471 Bacteria > Proteobacteria > Gammaproteobacteria > Pseudomonadales > Moraxellaceae > Acinetobacter
Host Escherichia coli
[NCBI] 		562 Bacteria > Proteobacteria > Gammaproteobacteria > Enterobacteriales > Enterobacteriaceae > Escherichia
Host Proteus mirabilis
[NCBI] 		584 Bacteria > Proteobacteria > Gammaproteobacteria > Enterobacteriales > Enterobacteriaceae > Proteus
Host Vibrio cholerae
[NCBI] 		666 Bacteria > Proteobacteria > Gammaproteobacteria > Vibrionales > Vibrionaceae > Vibrio
Host Salmonella enterica subsp. enterica serovar Typhimurium
[NCBI] 		90371 Bacteria > Proteobacteria > Gammaproteobacteria > Enterobacteriales > Enterobacteriaceae > Salmonella

Coding sequence (CDS)

Coding sequence (CDS)
Genbank protein accession
AAX45925.1 [NCBI]
Genbank nucleotide accession
AY848689 [NCBI]
CDS location
range 12190 -> 12987
strand +
CDS
ATGTCTGGTGCGCTGCAATGGTGGGAAACTATCGGCGCGGCTTCGGCGCAATATAACCTTGACCCGCGCCTAGTGGCCGGGGTTGTTCAAACGGAATCTTCCGGCAACCCCCGCACCACTTCCGGCGTGGGCGCTATGGGTTTAATGCAGCTTATGCCAGCGACCGCCAAAAGTTTAGGCGTAACAAACGCCTATGACCCGACACAAAACATTTATGGTGGCGCTGCCCTTTTGCGTGAAAACCTTGATAGATACGGCGATGTTAATACGGCGTTGCTTGCTTATCACGGCGGAACTAATCAAGCAAATTGGGGCGCTAAAACTAAATCCTATCCGGGTAAGGTTATGAAAAATATCAATTTGCTTTTCGGTAATAGCGGCCCGGTAGTAACGCCAGCGGCTGGAATCGCGCCAGTATCCGGGGCGCAAGAAATGACCGCCGTTAATATCAGCGACTATACCGCGCCTGATTTAACGGGGCTTACTATGGGGGCGGGTAGTCCTGACTTTACAGGCGGGGCTAGTGGTTCATGGGGCGAAGAAAACATTCCGTGGTATCGCGTAGATAAGCACGTTGCGAACGCGGCGGGTTCCGCTTATGACGCTGTTACCGATGCAGTAAGCGCCCCGGTTGAAGCAGCAGGAAACTACGCCTTGCGGGGCGTGGTAATTATTGCGGCGGTGGCAATTGTTGTTGTTGGTTTGTACTTCCTTTTTCAAGATGAAATTAACAGCGCCGCCATGAAAATGATTCCAGCCGGTAAGGCGGCAGGGGCAGCGGCTAAGGCTTTGGCATGA
Genbank protein accession
AAX45907.1 [NCBI]
Genbank nucleotide accession
AY848689 [NCBI]
CDS location
range 12535 -> 12987
strand +
CDS
ATGAAAAATATCAATTTGCTTTTCGGTAATAGCGGCCCGGTAGTAACGCCAGCGGCTGGAATCGCGCCAGTATCCGGGGCGCAAGAAATGACCGCCGTTAATATCAGCGACTATACCGCGCCTGATTTAACGGGGCTTACTATGGGGGCGGGTAGTCCTGACTTTACAGGCGGGGCTAGTGGTTCATGGGGCGAAGAAAACATTCCGTGGTATCGCGTAGATAAGCACGTTGCGAACGCGGCGGGTTCCGCTTATGACGCTGTTACCGATGCAGTAAGCGCCCCGGTTGAAGCAGCAGGAAACTACGCCTTGCGGGGCGTGGTAATTATTGCGGCGGTGGCAATTGTTGTTGTTGGTTTGTACTTCCTTTTTCAAGATGAAATTAACAGCGCCGCCATGAAAATGATTCCAGCCGGTAAGGCGGCAGGGGCAGCGGCTAAGGCTTTGGCATGA

Gene Ontology

Description Category Evidence (source)
GO:0000270 peptidoglycan metabolic process Biological process Inferred from Electronic Annotation (UniProt)
GO:0003796 lysozyme activity Molecular function Inferred from Electronic Annotation (UniProt)
GO:0008933 peptidoglycan lytic transglycosylase activity Molecular function Inferred from Electronic Annotation (TreeGrafter)
GO:0016020 membrane Cellular component Inferred from Electronic Annotation (UniProt)
GO:0031640 killing of cells of another organism Biological process Inferred from Electronic Annotation (UniProt)
GO:0039641 viral inner membrane Cellular component Inferred from Electronic Annotation (UniProt)
GO:0042742 defense response to bacterium Biological process Inferred from Electronic Annotation (UniProt)
GO:0055036 virion membrane Cellular component Inferred from Electronic Annotation (UniProt)
GO:0098932 symbiont entry into host cell via disruption of host cell wall peptidoglycan Biological process Inferred from Electronic Annotation (UniProt)
GO:0098994 symbiont entry into host cell via disruption of host cell envelope Biological process Inferred from Electronic Annotation (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
4.2.2.n1 peptidoglycan lytic exotransglycosylase
aka exomuramidase; murein lyase F 		in the MurNAc residue
Lyases
Carbon-oxygen lyases
Acting on polysaccharides
 experimental evidence used in manual assertion
ECO:0000269 		PubMed:10931330

Tertiary structure

No tertiary structures available.