Protein

UniProt accession
P13559 [UniProt]
Protein name
Endolysin
PhaLP type
endolysin

evidence: GO annotation

probability: 99 % (predicted by ML model)

Protein sequence
MQYTLWDIISRVESNGNLKALRFEPEYYQRRMERGDWDNSIIQNIRAANKCSLGTARMIYCSSWGAVQIMGFNLYLNGAFNLSVAHFMENEAYQVNEFRRFLLKNGLTEYTPERLASDKAARVKFAKVYNGAESYADLILQACQFYGVK
Physico‐chemical
properties
protein length:149 AA
molecular weight:17269,00000 Da
isoelectric point:8,75785
aromaticity:0,14094
hydropathy:-0,33758

Domains

Domains [InterPro]
IPR024408
25–134
IPR024408
IPR016284
1–149
IPR016284
Protein sequence: P13559
1 149
Legend: Pfam SMART CDD TIGRFAM HAMAP SUPFAM PRINTS Gene3D PANTHER Other

Taxonomy

  Name Taxonomy ID Lineage
Phage Enterobacteria phage PRD1 (Bacteriophage PRD1)
[NCBI] 		10658 Kalamavirales > Tectiviridae > Alphatectivirus > Alphatectivirus PRD1
Host Pseudomonas aeruginosa
[NCBI] 		287 Bacteria > Proteobacteria > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas
Host Pseudomonas fluorescens
[NCBI] 		294 Bacteria > Proteobacteria > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas
Host Pseudomonas putida
[NCBI] 		303 Bacteria > Proteobacteria > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas
Host Acinetobacter calcoaceticus
[NCBI] 		471 Bacteria > Proteobacteria > Gammaproteobacteria > Pseudomonadales > Moraxellaceae > Acinetobacter
Host Escherichia coli
[NCBI] 		562 Bacteria > Proteobacteria > Gammaproteobacteria > Enterobacteriales > Enterobacteriaceae > Escherichia
Host Proteus mirabilis
[NCBI] 		584 Bacteria > Proteobacteria > Gammaproteobacteria > Enterobacteriales > Enterobacteriaceae > Proteus
Host Vibrio cholerae
[NCBI] 		666 Bacteria > Proteobacteria > Gammaproteobacteria > Vibrionales > Vibrionaceae > Vibrio
Host Salmonella enterica subsp. enterica serovar Typhimurium
[NCBI] 		90371 Bacteria > Proteobacteria > Gammaproteobacteria > Enterobacteriales > Enterobacteriaceae > Salmonella

Coding sequence (CDS)

Coding sequence (CDS)
Genbank protein accession
AAA32451.1 [NCBI]
Genbank nucleotide accession
M22161 [NCBI]
CDS location
range 2679 -> >2973
strand +
CDS
ATGCAATATACACTTTGGGATATTATCAGCCGCGTGGAAAGCAACGGGAATTTAAAAGCGTTGCGCTTTGAACCTGAATACTATCAGCGGCGCATGGAGCGGGGCGATTGGGATAATTCCATTATTCAAAATATCCGCGCCGCCAATAAATGCAGCTTAGGTACTGCCCGCATGATTTATTGCAGTTCATGGGGCGCGGTTCAAATCATGGGATTTAATCTTTATTTGAACGGCGCATTTAATTTGAGCGTTGCGCATTTCATGGAAAATGAAGCGTATCAAGTAAATGAATTTC
Genbank protein accession
AAX45908.1 [NCBI]
Genbank nucleotide accession
AY848689 [NCBI]
CDS location
range 2679 -> 3128
strand +
CDS
ATGCAATATACACTTTGGGATATTATCAGCCGCGTGGAAAGCAACGGGAATTTAAAAGCGTTGCGCTTTGAACCTGAATACTATCAGCGGCGCATGGAGCGGGGCGATTGGGATAATTCCATTATTCAAAATATCCGCGCCGCCAATAAATGCAGCTTAGGTACTGCCCGCATGATTTATTGCAGTTCATGGGGCGCGGTTCAAATCATGGGATTTAATCTTTATTTGAACGGCGCATTTAATTTGAGCGTTGCGCATTTCATGGAAAATGAAGCGTATCAAGTAAATGAATTTCGGCGCTTTCTTTTGAAAAATGGATTAACTGAATATACGCCTGAAAGGCTGGCGAGTGATAAAGCGGCCCGCGTTAAATTCGCCAAGGTTTATAACGGCGCTGAAAGTTACGCGGATTTAATTTTGCAAGCCTGCCAATTTTACGGGGTGAAATAA
Genbank protein accession
CAA33104.1 [NCBI]
Genbank nucleotide accession
X14980 [NCBI]
CDS location
range 280 -> 729
strand +
CDS
ATGCAATATACACTTTGGGATATTATCAGCCGCGTGGAAAGCAACGGGAATTTAAAAGCGTTGCGCTTTGAACCTGAATACTATCAGCGGCGCATGGAGCGGGGCGATTGGGATAATTCCATTATTCAAAATATCCGCGCCGCCAATAAATGCAGCTTAGGTACTGCCCGCATGATTTATTGCAGTTCATGGGGCGCGGTTCAAATCATGGGATTTAATCTTTATTTGAACGGCGCATTTAATTTGAGCGTTGCGCATTTCATGGAAAATGAAGCGTATCAAGTAAATGAATTTCGGCGCTTTCTTTTGAAAAATGGATTAACTGAATATACGCCTGAAAGGCTGGCGAGTGATAAAGCGGCCCGCGTTAAATTCGCCAAGGTTTATAACGGCGCTGAAAGTTACGCGGATTTAATTTTGCAAGCCTGCCAATTTTACGGGGTGAAATAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity Molecular function Inferred from Electronic Annotation (UniProt)
GO:0016020 membrane Cellular component Inferred from Electronic Annotation (UniProt)
GO:0033922 peptidoglycan beta-N-acetylmuramidase activity Molecular function Inferred from Electronic Annotation (InterPro)
GO:0042742 defense response to bacterium Biological process Inferred from Electronic Annotation (UniProt)
GO:0044277 cell wall disassembly Biological process Inferred from Electronic Annotation (UniProt)
GO:0044659 viral release from host cell by cytolysis Biological process Inferred from Electronic Annotation (InterPro)
GO:0055036 virion membrane Cellular component Inferred from Electronic Annotation (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 lysozyme
aka muramidase 		D-glucosamine residues in chitodextrins
Hydrolases
Glycosylases
Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds
 experimental evidence used in manual assertion
ECO:0000269 		PubMed:11741849

Tertiary structure

No tertiary structures available.