Protein

UniProt accession

E5DV68 [UniProt]

Protein name

Lysin

PhaLP type

endolysin

evidence: ML prediction

probability: 99 % (predicted by ML model)

Protein sequence

MVRIVLDAGHGGKDSGAVGNGLREKDLTLNIVKKIGNLLAEYEGVEVHYTRTDDRFLELSERAEIANRLKADYFISVHINAGGGTGFESYIYNGNVSSATIAYQNVIHSEIMKAIGNVTDRGKKRANYAVLRETHMPALLTENLFIDNKNDAAKLDSEQFLLQVAHGHVQGIVKAFGLKKKATPQPQQKVSDKKLYRVQVGAFADRKNAERLADELKKKGYPVYITD

Physico‐chemical properties

protein length:	227 AA
molecular weight:	25161,00000 Da
isoelectric point:	9,16993
aromaticity:	0,07489
hydropathy:	-0,42026

Domains

Domains [InterPro]

IPR050695

3–178

IPR050695 IPR007730

IPR002508

63–173

IPR002508 IPR036680

IPR036680

175–227

IPR036680 IPR002508

IPR002508

4–173

IPR002508 IPR007730

Protein sequence: E5DV68

1 227

Legend: Pfam SMART CDD TIGRFAM HAMAP SUPFAM PRINTS Gene3D PANTHER Other

Domains [InterPro]

InterPro ID	Start	End	Source	Name
IPR050695	3	178	PANTHER	N-acetylmuramoyl-L-alanine amidase 3
IPR007730	193	224	PROSITE	Sporulation-like domain
IPR002508	63	173	Pfam	N-acetylmuramoyl-L-alanine amidase, catalytic domain
IPR036680	192	226	SUPFAM	Sporulation-like domain superfamily
IPR036680	175	227	SUPFAM	Sporulation-like domain superfamily
IPR002508	3	173	Pfam	N-acetylmuramoyl-L-alanine amidase, catalytic domain
IPR002508	4	173	Pfam	N-acetylmuramoyl-L-alanine amidase, catalytic domain
IPR007730	190	227	PROSITE	Sporulation-like domain

Taxonomy

	Name	Taxonomy ID	Lineage
Phage	Deep-sea thermophilic phage D6E [NCBI]	749413	No lineage information
Host	Geobacillus sp. E263 [NCBI]	391290	Bacteria > Firmicutes > Bacilli > Bacillales > Bacillaceae > Geobacillus

Coding sequence (CDS)

Genbank protein accession

ADE87506.1 [NCBI]

Genbank nucleotide accession

GU568037 [NCBI]

CDS location

range 20802 -> 21485
strand +

CDS

ATGGTACGTATCGTTTTAGACGCGGGACATGGCGGAAAAGATAGCGGAGCTGTAGGAAACGGGTTGAGAGAAAAAGACTTGACGTTGAACATCGTCAAAAAAATCGGTAATTTGCTTGCTGAATACGAGGGCGTAGAAGTACATTACACCCGTACAGACGACCGATTTCTTGAACTTTCCGAACGCGCGGAGATTGCAAATCGGTTGAAAGCAGACTATTTCATTTCTGTTCACATTAACGCCGGAGGCGGAACGGGGTTCGAGTCGTATATTTATAACGGAAACGTCAGCTCGGCAACAATCGCATATCAAAACGTGATTCATTCGGAGATCATGAAAGCAATTGGCAACGTGACTGATCGTGGTAAAAAGCGAGCCAACTATGCAGTATTGCGCGAAACGCATATGCCAGCATTATTGACAGAGAATTTGTTTATCGACAACAAAAATGATGCGGCCAAACTGGACAGTGAACAGTTCCTTTTGCAAGTCGCACATGGTCATGTACAAGGCATTGTCAAAGCTTTCGGTCTCAAGAAAAAAGCGACCCCTCAACCACAACAAAAAGTGTCTGACAAAAAATTATACCGCGTGCAAGTCGGGGCGTTTGCCGATCGGAAGAATGCCGAGCGATTGGCCGACGAGCTGAAGAAAAAAGGATACCCTGTCTATATCACTGACTAA

Gene Ontology

	Description	Category	Evidence (source)
GO:0008745	N-acetylmuramoyl-L-alanine amidase activity	Molecular function	Inferred from Electronic Annotation (UniProt)
GO:0009253	peptidoglycan catabolic process	Biological process	Inferred from Electronic Annotation (InterPro)
GO:0042834	peptidoglycan binding	Molecular function	Inferred from Electronic Annotation (InterPro)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available.