Protein

UniProt accession

D2J021 [UniProt]

Protein name

lysozyme

PhaLP type

endolysin

evidence: ML prediction

probability: 99 % (predicted by ML model)

Protein sequence

MKKKILAGALVALFFMPTAVFAAKGDQGVDWAIYQGEQGRFGYAHDKFAIAQIGGYNASGIYDQYTYKTQVASAIAQGKRAHTYIWYDTFGSMDIAKITMDYFLPRIQTPKNSIVALDFEHGASPDINANTETILYGMRRIKEAGYTPMYYSYKPFTLQYVDYQKIIKEFPNSLWIAAYPSYEVTPEPLYAYFPSMDGIAIWQFTSTYIAGGLDGNVDLTGITDNGYTDTDKPETDTPATDAGKETEDTPNTAVKVGDTVKVKFNVDAWATGEAIPDWVKGNSYKVQEVTGSRVLLEGILSWISKGDIELLPDATVVPDKQPEATHVVQYGETLSSIAYQYGTDYQALAALNGLTNPNLIYPGQVLKVNGSAVSNVYTVQYGDNLSSIATKLGTTYQALAQRNGLANPNLIYPGQTLNY

Physico‐chemical properties

protein length:	419 AA
molecular weight:	46088,00000 Da
isoelectric point:	4,85089
aromaticity:	0,12649
hydropathy:	-0,24153

Domains

Domains [InterPro]

IPR002053

29–212

IPR002053 IPR036779 IPR018392

IPR002053

25–243

IPR002053 IPR018392 IPR018392

IPR018392

376–419

IPR018392 IPR017853 IPR036779

IPR018077

111–230

IPR018077

Protein sequence: D2J021

1 419

Legend: Pfam SMART CDD TIGRFAM HAMAP SUPFAM PRINTS Gene3D PANTHER Other

Domains [InterPro]

InterPro ID	Start	End	Source	Name
IPR002053	29	212	Pfam	Glycoside hydrolase, family 25
IPR002053	25	243	Pfam	Glycoside hydrolase, family 25
IPR036779	376	417	SUPFAM	LysM domain superfamily
IPR018392	377	417	Pfam	LysM domain
IPR018392	325	369	Pfam	LysM domain
IPR018392	376	419	Pfam	LysM domain
IPR017853	23	225	SUPFAM	Glycoside hydrolase superfamily
IPR018392	324	368	Pfam	LysM domain
IPR036779	312	376	SUPFAM	LysM domain superfamily
IPR018077	111	230	SMART	Glycoside hydrolase, family 25 subgroup

Taxonomy

	Name	Taxonomy ID	Lineage
Phage	Enterococcus phage phiFL3B [NCBI]	673838	Phifelvirus > Phifelvirus FL3
Host	No host information

Coding sequence (CDS)

Genbank protein accession

ACZ64148.1 [NCBI]

Genbank nucleotide accession

GQ478087 [NCBI]

CDS location

range 38028 -> 39287
strand +

CDS

ATGAAAAAGAAAATTTTAGCAGGAGCGCTTGTCGCTCTGTTTTTTATGCCTACTGCTGTATTTGCCGCAAAAGGTGACCAAGGCGTTGACTGGGCGATTTATCAAGGTGAACAAGGGCGTTTTGGTTATGCACATGATAAATTCGCTATCGCTCAAATTGGCGGCTACAATGCTAGTGGTATTTACGATCAGTATACCTATAAAACTCAAGTAGCAAGTGCCATTGCTCAAGGAAAAAGAGCACATACTTATATTTGGTATGACACGTTCGGTAGCATGGATATTGCCAAAATAACAATGGATTATTTCTTACCACGTATTCAAACACCAAAAAATTCTATTGTAGCATTGGATTTTGAACATGGAGCTAGTCCTGATATAAACGCAAATACGGAAACAATCTTGTATGGTATGCGACGGATTAAAGAGGCAGGTTACACGCCAATGTATTATAGCTACAAGCCTTTTACGTTACAATACGTGGACTATCAGAAAATTATTAAAGAGTTTCCTAACTCTTTATGGATTGCTGCCTATCCTAGCTATGAGGTAACGCCAGAACCACTGTATGCTTATTTCCCAAGCATGGATGGTATCGCAATTTGGCAATTTACCTCCACTTATATTGCTGGTGGGTTAGATGGGAATGTTGATTTAACAGGTATTACTGATAATGGCTACACAGATACAGATAAGCCAGAGACGGACACACCAGCAACAGATGCAGGTAAAGAAACTGAAGATACGCCTAATACTGCAGTAAAAGTCGGTGACACAGTTAAAGTGAAATTTAATGTTGATGCTTGGGCAACTGGCGAAGCTATTCCAGATTGGGTAAAAGGAAACAGCTACAAAGTGCAAGAAGTAACTGGAAGTAGAGTATTGCTAGAAGGCATTTTGTCGTGGATTAGCAAAGGGGATATTGAACTATTGCCAGATGCAACAGTCGTCCCTGATAAGCAACCAGAAGCAACTCATGTGGTACAATACGGTGAAACGTTATCCAGCATTGCTTATCAATATGGAACAGACTATCAAGCGTTGGCGGCATTAAATGGATTGACAAATCCAAATCTAATCTATCCTGGTCAAGTTTTGAAAGTTAACGGATCAGCAGTAAGCAATGTTTACACGGTTCAATACGGCGACAATTTATCAAGTATTGCAACCAAACTAGGCACGACATACCAAGCTCTAGCGCAACGGAACGGATTAGCAAATCCTAACTTAATTTATCCAGGGCAAACATTGAACTATTGA

Gene Ontology

	Description	Category	Evidence (source)
GO:0003796	lysozyme activity	Molecular function	Inferred from Electronic Annotation (UniProt)
GO:0008932	lytic endotransglycosylase activity	Molecular function	Inferred from Electronic Annotation (UniProt)
GO:0009253	peptidoglycan catabolic process	Biological process	Inferred from Electronic Annotation (InterPro)
GO:0016998	cell wall macromolecule catabolic process	Biological process	Inferred from Electronic Annotation (InterPro)

Enzymatic activity

EC Number	Entry Name	Reaction Catalyzed	Classification	Evidence	Source
3.2.1.17	lysozyme aka muramidase	D-glucosamine residues in chitodextrins	Hydrolases Glycosylases Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds	match to sequence model evidence used in automatic assertion ECO:0000256	ARBA:ARBA00000632

Tertiary structure

No tertiary structures available.