Protein

UniProt accession

C9E2L3 [UniProt]

Protein name

Putative N-acetylmuramoyl-L-alanine amidase

PhaLP type

endolysin

evidence: ML prediction

probability: 99 % (predicted by ML model)

Protein sequence

MADTWLSPLAVSYQATQEWDEPDYLSGGQAGIHGGIDLAPKAGTNPPVYSAKSGTVEEVVPNHPIGGNYIVIRHMDNYWTYYGHLATINVSVGQQVTNQTVLGLCGATGGATGIHLHFEVWRGGKWQRINPREVINLDGSGRDSSNNGGNGGIYTGGALLNAGKSISESNIRLIISAGKKYNIKPSFMIAQMFIESHWGDPSISIVGSKDNNWAGISEPFSVPADLGINMSRGSARPVGEGGYYIHFATMNDFFKAYAFVLSKRNGLYNVEGANSIEEYCKGLFRIGGANSDYAATGYQNYFNMLIPTYNSINKQNPGKLAQIDASTEEITNNGGLTTMQCLYERPINPNTGALDINGSATTMMFCNGVNTRRVYHNDEVNIVKELYRKNNGKEIPVYYKKDWPKTSPWYIRLEAMFPVVK

Physico‐chemical properties

protein length:	421 AA
molecular weight:	46133,00000 Da
isoelectric point:	6,75903
aromaticity:	0,10689
hydropathy:	-0,36508

Domains

Domains [InterPro]

IPR016047

32–125

IPR016047 IPR002901

IPR011055

7–133

IPR011055 IPR002901

IPR050570

15–134

IPR050570

IPR011055

11–139

IPR011055

Protein sequence: C9E2L3

1 421

Legend: Pfam SMART CDD TIGRFAM HAMAP SUPFAM PRINTS Gene3D PANTHER Other

Domains [InterPro]

InterPro ID	Start	End	Source	Name
IPR016047	32	125	Pfam	Peptidase M23
IPR011055	7	133	SUPFAM	Duplicated hybrid motif
IPR002901	159	299	SMART	Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain
IPR002901	174	309	SMART	Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain
IPR050570	15	134	PANTHER	Bacterial cell wall metabolism enzyme
IPR011055	11	139	SUPFAM	Duplicated hybrid motif

Taxonomy

	Name	Taxonomy ID	Lineage
Phage	Enterococcus phage phiEf11 [NCBI]	663241	No lineage information
Host	Enterococcus faecalis [NCBI]	1351	Bacteria > Firmicutes > Bacilli > Lactobacillales > Enterococcaceae > Enterococcus

Coding sequence (CDS)

Genbank protein accession

ACV83371.1 [NCBI]

Genbank nucleotide accession

GQ452243 [NCBI]

CDS location

range 21523 -> 22788
strand +

CDS

ATGGCAGACACATGGTTAAGTCCTCTTGCTGTTTCTTATCAAGCAACTCAAGAATGGGATGAACCTGATTATTTGAGCGGAGGGCAAGCAGGAATTCACGGAGGCATTGACTTAGCTCCAAAAGCAGGTACTAATCCACCTGTTTATTCAGCTAAATCTGGGACAGTAGAAGAGGTAGTACCAAATCATCCAATTGGTGGTAATTACATTGTTATCAGACATATGGATAACTACTGGACCTATTATGGGCATTTAGCAACTATAAATGTATCAGTAGGACAACAAGTAACAAATCAAACGGTTCTTGGATTATGTGGAGCAACTGGGGGTGCCACAGGTATCCATCTTCATTTTGAAGTATGGCGTGGTGGTAAATGGCAGAGAATCAATCCACGAGAAGTAATTAATTTAGATGGATCTGGCAGAGACTCTAGTAATAACGGTGGCAATGGTGGAATTTATACAGGCGGAGCTTTATTAAATGCAGGAAAAAGCATTTCAGAATCAAATATTCGTCTAATCATTTCTGCTGGAAAAAAATATAATATCAAGCCAAGTTTTATGATTGCACAAATGTTTATTGAAAGTCATTGGGGAGATCCAAGCATTTCAATTGTTGGAAGTAAAGACAATAATTGGGCAGGAATTTCAGAACCTTTTAGCGTTCCAGCTGATTTAGGAATTAATATGAGTCGTGGATCAGCAAGACCAGTTGGTGAAGGTGGTTATTATATTCATTTTGCAACCATGAACGATTTTTTTAAAGCATATGCATTTGTATTATCAAAAAGAAATGGCTTATATAATGTTGAAGGTGCAAATTCAATTGAAGAATACTGTAAAGGCTTATTTCGCATAGGTGGAGCAAATTCAGACTATGCCGCGACAGGCTATCAAAATTATTTTAATATGTTAATACCAACTTATAATTCAATAAACAAACAAAATCCTGGTAAACTTGCACAAATTGATGCAAGTACTGAAGAAATTACTAATAATGGAGGACTGACAACTATGCAATGTTTATATGAACGACCAATTAATCCGAATACTGGAGCTTTAGATATAAATGGCTCAGCAACTACAATGATGTTTTGTAATGGGGTCAATACACGAAGAGTATATCATAATGATGAAGTTAATATTGTTAAAGAGCTATATCGTAAAAACAATGGAAAAGAAATCCCGGTATATTATAAAAAAGATTGGCCTAAAACTTCGCCATGGTATATTCGACTAGAGGCAATGTTTCCAGTAGTGAAATGA

Gene Ontology

	Description	Category	Evidence (source)
GO:0004040	amidase activity	Molecular function	Inferred from Electronic Annotation (UniProt)
GO:0004222	metalloendopeptidase activity	Molecular function	Inferred from Electronic Annotation (InterPro)
GO:0031640	killing of cells of another organism	Biological process	Inferred from Electronic Annotation (UniProt)
GO:0042742	defense response to bacterium	Biological process	Inferred from Electronic Annotation (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available.