Protein

UniProt accession

A7DYC5 [UniProt]

Protein name

Lysozyme

PhaLP type

endolysin

evidence: ML prediction

probability: 99 % (predicted by ML model)

Protein sequence

MTSLKKGDYFIDVSGYQPADLHGVFSASGTNKTIIKLTESTGYYNTSAPSQVATSDCIGFYHFARFGGSVAQAQTEANFFLSTLAKTDIKYLVCDYEDSASGDKQANTNAVLAFMDVIASAGYKPIYYSYRPFTLENIYHDQLNAKYPNSTWIAAYPNYAVTPDPVWSIFPSIDGARWWQFTSTAIASGLDKNVVLLDDDGAVDEILKGLENDMDYTIREKTGKYPYMVLTHGSAVAVGHIDTISAFQSAGAKDLNLDTDDYQRLIAVINKGK

Physico‐chemical properties

protein length:	273 AA
molecular weight:	29995,00000 Da
isoelectric point:	4,84737
aromaticity:	0,12821
hydropathy:	-0,20366

Domains

Domains [InterPro]

IPR002053

7–210

IPR002053

IPR008270

12–45

IPR008270 IPR018077

IPR002053

11–189

IPR002053

IPR017853

7–195

IPR017853

Protein sequence: A7DYC5

1 273

Legend: Pfam SMART CDD TIGRFAM HAMAP SUPFAM PRINTS Gene3D PANTHER Other

Domains [InterPro]

InterPro ID	Start	End	Source	Name
IPR002053	7	210	Pfam	Glycoside hydrolase, family 25
IPR008270	12	45	PROSITE	Glycosyl hydrolases family 25, active site
IPR018077	90	206	SMART	Glycoside hydrolase, family 25 subgroup
IPR002053	11	189	Pfam	Glycoside hydrolase, family 25
IPR017853	7	195	SUPFAM	Glycoside hydrolase superfamily

Taxonomy

	Name	Taxonomy ID	Lineage
Phage	Streptococcus phage M102 [NCBI]	372457	Aliceevansviridae >
Host	Streptococcus mutans [NCBI]	1309	Bacteria > Firmicutes > Bacilli > Lactobacillales > Streptococcaceae > Streptococcus

Coding sequence (CDS)

Genbank protein accession

CAO77369.1 [NCBI]

Genbank nucleotide accession

AM749121 [NCBI]

CDS location

range 20058 -> 20879
strand +

CDS

ATGACCTCGCTAAAAAAAGGTGATTATTTTATCGACGTAAGTGGCTATCAACCCGCAGATTTGCACGGGGTCTTCTCTGCTTCTGGCACTAATAAAACGATAATCAAACTGACTGAGTCGACTGGTTATTATAACACCAGCGCCCCTAGTCAAGTTGCAACTAGTGATTGCATTGGATTTTACCATTTCGCACGATTTGGGGGCTCTGTGGCACAAGCGCAAACAGAAGCGAACTTCTTTCTTAGCACACTAGCTAAGACAGACATTAAATATTTAGTCTGTGACTATGAAGACTCTGCGAGCGGTGATAAGCAAGCAAACACTAATGCTGTATTAGCGTTTATGGACGTAATCGCAAGCGCTGGCTATAAGCCTATATACTACTCATATAGACCATTTACGCTGGAAAATATCTATCACGACCAGCTAAACGCCAAGTATCCAAATAGCACTTGGATAGCAGCATATCCAAACTATGCAGTAACGCCTGACCCCGTTTGGTCAATATTCCCGTCAATCGACGGAGCTAGATGGTGGCAATTCACCAGCACAGCGATTGCTAGTGGACTTGATAAAAATGTGGTGCTGTTAGATGATGATGGCGCAGTAGACGAAATTTTGAAAGGACTAGAAAACGACATGGATTACACAATTAGAGAAAAAACAGGAAAATATCCCTACATGGTCTTGACTCATGGCTCCGCTGTAGCAGTAGGGCATATTGACACTATCTCAGCGTTTCAAAGCGCAGGGGCTAAAGACCTCAATCTCGACACAGACGACTATCAACGTTTGATTGCAGTAATTAACAAAGGAAAATAA

Gene Ontology

	Description	Category	Evidence (source)
GO:0003796	lysozyme activity	Molecular function	Inferred from Electronic Annotation (UniProt)
GO:0009253	peptidoglycan catabolic process	Biological process	Inferred from Electronic Annotation (InterPro)
GO:0016052	carbohydrate catabolic process	Biological process	Inferred from Electronic Annotation (TreeGrafter)
GO:0016998	cell wall macromolecule catabolic process	Biological process	Inferred from Electronic Annotation (InterPro)

Enzymatic activity

EC Number	Entry Name	Reaction Catalyzed	Classification	Evidence	Source
3.2.1.17	lysozyme aka muramidase	D-glucosamine residues in chitodextrins	Hydrolases Glycosylases Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds	match to sequence model evidence used in automatic assertion ECO:0000256	ARBA:ARBA00000632

Tertiary structure

No tertiary structures available.