Protein

UniProt accession

A0AAX4QAV4 [UniProt]

Protein name

Endolysin

PhaLP type

endolysin

evidence: GO annotation

probability: 99 % (predicted by ML model)

Protein sequence

MAFTDDFLKKIKGGAYASWKNYKVLPSVVAAQAALESNWGRSSLATQGKNLFGVKGSYKGQSIVFPTQEWTGGGYVTINDAFAKYPSWDVSIVEHGKLIAENARYRAAIGKTDPLAQITAIWSAGYATDPAYPSKIMSVINANNLRAWDLDAFSGGDGGGFSGDIGGGNGYKNFSENLIKKNGTTRPGFKLEAMQAIVVHDIQSSSNLGGIRNILNSGNGGQKMGYHVIVSENDAQLVVPFTEGVYHAERGKSLVAGMSNPNKKTISIGVVTKRSLSNFSTNLNIKLALVIAEICRTYKIPATAVLPAWQVDGVSEPISWYNNPFLYTAFVGMVSDAIEKGEDVITNPDYDSGGGGTGADGLIPNGEGAIKNIIKEANDLLGSMTYSWTRPAQIRKGGFGDCSSFCQYLYQKHAKVDIGSYTDAQWFGSWGKKVNVKDARAGDLIFFAGTYATNMTTTHIGIVVGGGKMIDFGSTPGPKLNNYNDSYWGPKIYGVKRIFSDADYNQSQSGGGKPSKPTIDPKGTYVVNVKKSVVATNADVGGVSQRRLSSNEVYRVQEIGKTSLQLASNELWVPKSSDAITVSRLSTPSSPIGAISTKLPTKVYSAPTYVAEPAIEKGTPRILPEKTSMNIYAVENGFAQVDLEKNHWAVANSTYATLNIDLSEEFVEDINFEQGIPTSTTVRGRYEPEDFITVENSLPIKNGLAVVAHPDLLDIGSVINIEIPSATKYNRKAVVVSNKLNDSDGNVLELIFTNQGDQYNFGGRTGIITLLEVLDNDVDITKFMNNPEGYEQTKAIPPKTPEGGMLGEPK

Physico‐chemical properties

protein length:	810 AA
molecular weight:	87288,00000 Da
isoelectric point:	6,51184
aromaticity:	0,09259
hydropathy:	-0,27519

Domains

Domains [InterPro]

IPR036505

171–330

IPR036505 IPR038765 IPR002901

IPR036505

179–325

IPR036505 IPR000064 IPR051056

IPR000064

400–497

IPR000064 IPR002901

Protein sequence: A0AAX4QAV4

1 810

Legend: Pfam SMART CDD TIGRFAM HAMAP SUPFAM PRINTS Gene3D PANTHER Other

Domains [InterPro]

InterPro ID	Start	End	Source	Name
IPR036505	171	330	Gene3D	N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily
IPR038765	364	500	SUPFAM	Papain-like cysteine peptidase superfamily
IPR036505	179	325	Gene3D	N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily
IPR000064	367	499	PROSITE	Endopeptidase, NLPC/P60 domain
IPR002901	15	145	SMART	Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain
IPR000064	400	497	PROSITE	Endopeptidase, NLPC/P60 domain
IPR051056	3	149	PANTHER	Glycosyl Hydrolase Family 73
IPR002901	4	149	SMART	Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain

Taxonomy

	Name	Taxonomy ID	Lineage
Phage	Enterococcus phage VRE9_4 [NCBI]	3141818	No lineage information
Host	No host information

Coding sequence (CDS)

Genbank protein accession

XAG97664.1 [NCBI]

Genbank nucleotide accession

PP680570 [NCBI]

CDS location

range 39559 -> 41991
strand +

CDS

ATGGCTTTTACAGATGATTTTTTAAAAAAGATAAAAGGTGGAGCTTATGCTAGTTGGAAAAACTATAAGGTCTTACCTTCTGTTGTTGCCGCTCAGGCAGCATTAGAGTCAAACTGGGGTAGAAGTTCCCTAGCGACACAAGGGAAAAATCTGTTTGGGGTAAAAGGAAGTTATAAAGGACAGTCTATTGTCTTTCCTACCCAAGAGTGGACTGGTGGAGGATATGTAACTATTAATGACGCCTTTGCTAAGTATCCTAGTTGGGATGTTTCCATTGTGGAACATGGTAAATTAATTGCAGAAAATGCTCGTTATCGTGCTGCTATTGGGAAAACAGATCCTTTAGCCCAAATCACAGCAATTTGGAGCGCTGGTTATGCAACAGATCCTGCTTATCCAAGCAAAATTATGTCAGTTATTAATGCTAATAATTTAAGAGCATGGGATTTAGACGCTTTTTCTGGTGGAGATGGCGGAGGATTCAGTGGAGATATAGGTGGAGGAAATGGTTATAAAAACTTTTCTGAAAATCTTATCAAGAAAAATGGTACTACAAGACCAGGGTTTAAATTAGAAGCAATGCAAGCCATTGTAGTGCATGATATTCAAAGTAGTTCTAATTTAGGTGGAATAAGGAATATTCTTAATTCTGGAAATGGTGGACAAAAAATGGGTTATCATGTTATTGTCTCAGAAAATGACGCCCAACTAGTAGTACCCTTTACAGAAGGAGTTTATCATGCGGAGAGAGGCAAAAGCTTAGTTGCTGGCATGAGTAATCCAAATAAAAAAACTATCTCTATTGGAGTAGTAACAAAACGTTCACTTTCTAATTTTTCTACCAACCTAAATATTAAATTAGCCTTAGTTATTGCGGAAATATGTAGAACATATAAAATACCTGCAACCGCTGTATTACCAGCTTGGCAAGTAGATGGAGTAAGCGAACCTATTAGCTGGTATAATAATCCTTTCTTATATACTGCCTTTGTAGGAATGGTAAGTGATGCTATTGAAAAAGGAGAAGATGTAATTACAAATCCTGACTATGACAGTGGTGGAGGAGGAACTGGTGCTGATGGGTTAATACCAAATGGAGAAGGCGCAATTAAGAATATTATTAAAGAAGCCAATGATTTGCTTGGATCAATGACCTATTCTTGGACAAGACCTGCCCAAATAAGAAAAGGCGGTTTTGGAGACTGTTCTTCATTCTGTCAATATCTATACCAAAAACATGCTAAGGTTGATATAGGAAGTTATACTGATGCCCAATGGTTTGGAAGTTGGGGTAAAAAAGTTAACGTTAAAGATGCTAGAGCAGGGGACTTAATATTCTTTGCTGGAACCTATGCTACTAATATGACAACCACTCATATTGGAATTGTTGTTGGTGGAGGAAAAATGATTGACTTTGGTTCTACACCAGGTCCAAAATTAAACAATTATAATGATAGTTATTGGGGACCAAAAATCTATGGTGTGAAAAGAATTTTTTCTGATGCAGATTATAACCAATCCCAATCAGGAGGAGGAAAACCTTCAAAACCTACAATTGACCCTAAAGGAACATATGTTGTTAATGTTAAAAAATCAGTTGTTGCAACTAACGCTGATGTCGGCGGAGTATCACAAAGAAGATTATCTTCCAATGAAGTTTATAGAGTACAAGAAATTGGTAAAACTAGTTTACAATTAGCCTCTAATGAATTATGGGTGCCTAAGAGTAGTGATGCAATAACAGTTTCACGATTATCTACACCATCTTCTCCTATTGGAGCTATTTCAACTAAATTACCTACAAAAGTATATTCTGCTCCTACTTATGTAGCAGAACCAGCAATAGAGAAAGGAACGCCAAGAATTCTTCCTGAAAAAACAAGTATGAATATTTACGCTGTAGAGAATGGTTTTGCTCAAGTGGATTTAGAAAAAAATCATTGGGCTGTAGCTAATTCTACATATGCGACTTTGAATATTGATTTATCTGAAGAATTTGTAGAAGATATTAATTTTGAACAGGGCATTCCAACTTCAACTACTGTAAGAGGACGGTATGAACCAGAAGACTTTATTACAGTAGAGAATAGTTTGCCAATTAAAAATGGATTAGCTGTAGTTGCTCATCCAGATTTATTGGATATTGGTTCAGTAATTAATATAGAAATTCCATCAGCAACTAAATATAATAGAAAAGCAGTTGTGGTATCAAATAAATTAAATGATTCAGATGGAAACGTATTAGAATTGATATTTACAAACCAAGGAGATCAATATAATTTTGGAGGAAGAACTGGAATTATTACATTATTAGAAGTATTAGATAATGATGTAGATATTACAAAATTTATGAATAATCCAGAAGGTTACGAACAAACTAAAGCTATCCCTCCAAAAACTCCAGAAGGAGGTATGTTAGGTGAGCCAAAGTAA

Gene Ontology

	Description	Category	Evidence (source)
GO:0001897	symbiont-mediated cytolysis of host cell	Biological process	Inferred from Electronic Annotation (InterPro)
GO:0004040	amidase activity	Molecular function	Inferred from Electronic Annotation (UniProt)
GO:0008234	cysteine-type peptidase activity	Molecular function	Inferred from Electronic Annotation (UniProt)
GO:0008745	N-acetylmuramoyl-L-alanine amidase activity	Molecular function	Inferred from Electronic Annotation (UniProt)
GO:0009253	peptidoglycan catabolic process	Biological process	Inferred from Electronic Annotation (InterPro)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available.