Protein

UniProt accession

A0A0K1LK43 [UniProt]

Protein name

Baseplate central spike protein

PhaLP type

endolysin

evidence: UniProt function annotation

probability: 99 % (predicted by ML model)

Protein sequence

MINMSDNVSWFVGVVEDRMDPLQQGRVRVRVWGMHPYEKVQGPVKGLRTEDLPWMSVLMPTSSASVSGIQTAMTGMVPGTQVYGHFLDKWKLNGLVLGTYGSASRQKANPNEGFSDPTGQYPLYLGNDAAALNRGGEVGYDATSNVIQDANTDVGINPDGLDLSQVKPDDNPNFTIENMLHRDEGLRLKVYWDTEGYPTIGIGHLITPQPIRDMNRINKILSNQVGREVKGNPGAISMDEASKLFQEDLKKVQNDIGRHSVVGPVYNKENRSRQMALENMAFQMGLGGLAKFRGMLSAMLIGDYKKAFEEARNSVWFNQTKGRASRVSMIILTGNMESYGIMAPKERSFNGRSYRMIQTFVAPTNSDPADPWTPEDTRILFKEPDSSYKGEYPYVQTMQTEGGHIQEFDNTPGQERYRLIHPTGSYEEVAPDGRKTSKTVADGYYMTQGDSNTYVGGNNKVNVGGDETYYNMANVRRQTDGNETIHIRGNEEKTVEGNGTLRVKGNVTVIVEGNADVTVKGDATTLVEGNETRTTNGNLNWTVNGTVSWTCAGAWSETMASMSSIASGQYTIDGSRIDIG

Physico‐chemical properties

protein length:	580 AA
molecular weight:	63970,00000 Da
isoelectric point:	5,41854
aromaticity:	0,07931
hydropathy:	-0,58948

Domains

Domains [InterPro]

IPR052619

171–338

IPR052619 IPR010609

IPR046397

3–580

IPR046397

IPR001165

177–196

IPR001165 IPR009590

IPR023346

132–344

IPR023346

IPR002196

183–316

IPR002196

IPR023347

174–342

IPR023347

Protein sequence: A0A0K1LK43

1 580

Legend: Pfam SMART CDD TIGRFAM HAMAP SUPFAM PRINTS Gene3D PANTHER Other

Domains [InterPro]

InterPro ID	Start	End	Source	Name
IPR052619	171	338	PANTHER	Bacteriophage lysozyme-like
IPR046397	3	580	HAMAP	Pre-baseplate central spike protein Gp5
IPR001165	177	196	PRINTS	T4-type lysozyme
IPR023346	132	344	SUPFAM	Lysozyme-like domain superfamily
IPR009590	33	173	Pfam	Protein Gp5, N-terminal OB-fold domain
IPR002196	183	316	Pfam	Glycoside hydrolase, family 24
IPR010609	513	534	Pfam	Gp5, C-terminal
IPR023347	174	342	Gene3D	Lysozyme domain superfamily

Taxonomy

	Name	Taxonomy ID	Lineage
Phage	Escherichia phage QL01 [NCBI]	1673871	Straboviridae > Dhakavirus > Dhakavirus ql01
Host	Enterobacteriales [NCBI]	91347	Bacteria > Proteobacteria > Gammaproteobacteria >

Coding sequence (CDS)

Genbank protein accession

AKU42809.1 [NCBI]

Genbank nucleotide accession

KT176190 [NCBI]

CDS location

range 75687 -> 77429
strand +

CDS

ATGATTAACATGTCTGATAATGTAAGTTGGTTCGTCGGTGTAGTTGAAGACCGAATGGACCCACTCCAACAAGGCCGAGTACGCGTGCGCGTATGGGGTATGCATCCATATGAAAAAGTACAAGGCCCTGTAAAAGGCCTTCGTACAGAAGATTTACCATGGATGTCGGTATTAATGCCTACATCTTCTGCCTCTGTTTCAGGTATCCAAACCGCTATGACTGGTATGGTCCCCGGTACACAAGTTTATGGTCACTTTCTTGATAAGTGGAAATTAAACGGACTTGTCCTTGGTACATACGGTTCCGCTTCAAGACAGAAGGCTAATCCTAATGAAGGGTTTAGTGACCCTACAGGCCAATATCCGCTTTATTTAGGTAACGATGCTGCTGCTTTAAACCGAGGTGGTGAAGTTGGATACGATGCCACTTCTAACGTAATACAAGATGCAAACACTGATGTAGGTATTAATCCTGACGGGTTGGATTTAAGTCAAGTCAAACCAGACGATAATCCTAATTTCACAATAGAAAACATGCTTCATCGTGATGAAGGGCTTAGACTGAAGGTATATTGGGATACCGAAGGTTATCCTACTATAGGTATAGGCCACCTTATCACACCACAACCTATTAGAGATATGAATCGAATAAACAAAATATTATCTAATCAGGTAGGACGAGAAGTTAAAGGTAACCCTGGTGCAATATCAATGGATGAGGCTTCTAAATTATTCCAAGAAGACCTTAAAAAAGTCCAAAACGATATAGGTCGGCATAGTGTTGTAGGTCCTGTTTACAATAAAGAAAACCGTTCAAGACAAATGGCTCTTGAAAACATGGCTTTCCAAATGGGATTAGGTGGATTGGCTAAATTCCGTGGAATGCTTAGTGCAATGCTAATAGGCGATTATAAAAAGGCATTTGAGGAAGCTCGTAATTCAGTATGGTTTAACCAAACTAAAGGTCGCGCATCAAGGGTGTCAATGATTATCCTCACAGGTAACATGGAATCATATGGTATTATGGCCCCTAAAGAAAGGTCATTTAATGGCCGTTCGTATAGAATGATTCAAACCTTTGTGGCCCCTACAAATTCAGACCCTGCCGACCCGTGGACTCCAGAAGACACAAGGATTCTTTTTAAAGAACCTGATTCTAGTTATAAAGGCGAATATCCATATGTCCAAACCATGCAAACTGAAGGCGGGCATATCCAAGAATTCGATAATACCCCAGGGCAAGAACGATACCGTTTAATCCATCCTACCGGTAGTTATGAAGAAGTTGCTCCTGATGGACGTAAAACTTCTAAGACGGTAGCCGATGGTTATTATATGACCCAAGGCGATTCAAATACTTATGTTGGTGGTAATAATAAAGTCAACGTTGGTGGCGATGAAACCTATTATAATATGGCAAACGTGCGTCGTCAGACTGATGGAAACGAAACCATCCATATTCGCGGTAATGAAGAGAAAACTGTAGAAGGTAATGGCACCCTTCGTGTTAAAGGTAATGTTACTGTTATTGTTGAAGGAAATGCTGATGTTACTGTTAAGGGTGATGCAACTACCTTAGTTGAAGGTAATGAAACTCGTACGACCAATGGTAATTTAAATTGGACAGTAAACGGTACCGTTTCTTGGACTTGTGCAGGTGCGTGGTCCGAGACTATGGCTTCAATGAGTTCTATTGCATCTGGTCAATATACTATTGATGGTTCGAGGATTGACATTGGCTAA

Gene Ontology

	Description	Category	Evidence (source)
GO:0003796	lysozyme activity	Molecular function	Inferred from Electronic Annotation (UniProt)
GO:0009253	peptidoglycan catabolic process	Biological process	Inferred from Electronic Annotation (InterPro)
GO:0016998	cell wall macromolecule catabolic process	Biological process	Inferred from Electronic Annotation (InterPro)
GO:0031640	killing of cells of another organism	Biological process	Inferred from Electronic Annotation (UniProt)
GO:0042742	defense response to bacterium	Biological process	Inferred from Electronic Annotation (UniProt)
GO:0098003	viral tail assembly	Biological process	Inferred from Electronic Annotation (UniProt)
GO:0098025	virus tail, baseplate	Cellular component	Inferred from Electronic Annotation (UniProt)
GO:0098932	symbiont entry into host cell via disruption of host cell wall peptidoglycan	Biological process	Inferred from Electronic Annotation (UniProt)
GO:0098994	symbiont entry into host cell via disruption of host cell envelope	Biological process	Inferred from Electronic Annotation (UniProt)

Enzymatic activity

EC Number	Entry Name	Reaction Catalyzed	Classification	Evidence	Source
3.2.1.17	lysozyme aka muramidase	D-glucosamine residues in chitodextrins	Hydrolases Glycosylases Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds	match to sequence model evidence used in automatic assertion ECO:0000256	HAMAP-Rule:MF_04151

Tertiary structure

No tertiary structures available.