Protein

UniProt accession
A0A0A7HG62 [UniProt]
Protein name
Baseplate central spike protein
PhaLP type
endolysin

evidence: UniProt function annotation

probability: 99 % (predicted by ML model)

Protein sequence
MINMSDSVSWFVGVVEDRMDPLQQGRVRVRVWGMHPYEKAQGPVKGIRTEDLPWMSVLMPTSSASVSGIQTAMTGMVPGTQVYGHFLDKWKLNGLVIGTYGSASRQKANPNEGFSDPTGQYPLYVGNDAAALNRGGEVGYDATSNVIQDANLDLGINPDGLDLSQVKPDDNPNFTIENMLHRDEGLRLKVYWDSEGYPTVGIGHLITPQKIRNMEQINLILSKQVDREVKGNPGTISMDEASKLFQEDLKKVQKDIGSTNALLSQVYNQENRSRQMALENMAFQMGVGGLAKFRSMLGNMLVKDYKAAFDNARDSVWFQQTKGRASRVSMIILTGNMESYGIMAPKEGGRARMTTFAEPREADPADPWTPEDTRILFKEPESSYKGEYPYIQTMQTEGGHIQEFDNTPGQERYRLIHPTGSYEEVAPDGRKTSKTVADGYYMTQGDSSTYVGGNNKVNVGGDETYYNMANVRRQTDGNESIHIRGNETKTIEGDGTIIVKGNVSILVEGNAEITVKGDAKTLVEGNHDYTVNGNVKWSVNGNVDMTVAGNWSETMASMSSIASGQYTIDGSRIDIG
Physico‐chemical
properties
protein length:576 AA
molecular weight:63456,00000 Da
isoelectric point:5,12940
aromaticity:0,07639
hydropathy:-0,56615

Domains

Domains [InterPro]
IPR023347
177–343
IPR023347 IPR010609 IPR009590
IPR023346
132–345
IPR023346
IPR052619
172–339
IPR052619
IPR046397
3–576
IPR046397
IPR002196
183–312
IPR002196
IPR001165
177–196
IPR001165
Protein sequence: A0A0A7HG62
1 576
Legend: Pfam SMART CDD TIGRFAM HAMAP SUPFAM PRINTS Gene3D PANTHER Other

Taxonomy

  Name Taxonomy ID Lineage
Phage Escherichia phage vB_EcoM_VR25
[NCBI] 		1567028 Straboviridae > Gaprivervirus > Gaprivervirus vr25
Host Escherichia coli
[NCBI] 		562 Bacteria > Proteobacteria > Gammaproteobacteria > Enterobacteriales > Enterobacteriaceae > Escherichia

Coding sequence (CDS)

Coding sequence (CDS)
Genbank protein accession
AIZ02510.1 [NCBI]
Genbank nucleotide accession
KP007361 [NCBI]
CDS location
range 76323 -> 78053
strand +
CDS
ATGATTAATATGTCAGATAGTGTAAGTTGGTTCGTCGGTGTAGTTGAAGACCGAATGGACCCGCTTCAGCAAGGCCGTGTGCGCGTTCGCGTGTGGGGTATGCATCCATATGAGAAAGCACAAGGTCCTGTGAAAGGTATCAGAACCGAAGACCTCCCTTGGATGTCTGTATTGATGCCAACATCATCTGCGTCGGTTTCTGGAATTCAAACCGCAATGACTGGTATGGTACCAGGGACTCAGGTATATGGTCACTTTTTGGACAAGTGGAAGCTCAACGGTCTTGTCATTGGTACATATGGTTCAGCCTCAAGACAAAAAGCAAATCCTAACGAAGGCTTCTCTGACCCCACGGGACAATATCCACTTTATGTCGGTAATGATGCTGCAGCGCTTAACCGTGGGGGTGAAGTTGGTTATGATGCTACTTCGAACGTAATCCAGGATGCAAACCTTGACCTTGGTATTAACCCTGATGGCCTTGATTTAAGCCAGGTTAAGCCAGATGATAATCCCAATTTCACAATTGAAAATATGCTTCACCGCGATGAAGGTCTTCGTTTGAAAGTATATTGGGACTCCGAAGGATATCCGACTGTCGGGATTGGTCACCTTATTACCCCGCAAAAAATTCGTAATATGGAACAAATCAACTTGATATTATCAAAGCAAGTTGACCGTGAAGTTAAAGGAAACCCAGGCACAATATCCATGGATGAAGCTTCGAAGTTATTCCAGGAAGACCTTAAGAAAGTACAAAAAGATATTGGCAGTACAAATGCGCTTTTATCCCAGGTTTATAACCAAGAAAACAGGTCAAGACAAATGGCCCTGGAAAACATGGCATTCCAAATGGGTGTAGGTGGACTGGCTAAGTTTCGTAGCATGCTAGGCAATATGCTTGTTAAAGATTATAAAGCCGCTTTCGATAACGCAAGGGATTCGGTTTGGTTCCAACAGACAAAAGGCCGGGCATCAAGGGTATCGATGATTATCTTGACTGGCAACATGGAGTCATATGGCATCATGGCTCCAAAAGAAGGTGGACGTGCTCGCATGACTACTTTTGCCGAACCAAGAGAAGCCGACCCGGCTGACCCGTGGACTCCAGAAGATACAAGGATTCTGTTTAAAGAACCAGAATCAAGTTACAAAGGCGAATATCCTTACATACAGACAATGCAAACCGAAGGCGGTCACATTCAGGAATTCGATAACACTCCTGGACAAGAACGTTATCGACTGATTCACCCGACTGGCTCCTATGAGGAAGTTGCTCCGGATGGTCGTAAGACTTCAAAGACAGTAGCCGATGGTTATTATATGACCCAGGGCGATTCGAGCACTTATGTTGGCGGTAATAATAAAGTCAACGTCGGCGGCGATGAAACCTATTACAATATGGCTAACGTTCGCAGACAAACCGATGGAAACGAAAGCATTCATATCAGAGGGAATGAAACCAAAACTATCGAAGGTGACGGTACAATTATTGTCAAAGGTAATGTAAGTATTCTGGTCGAAGGTAATGCTGAAATAACTGTTAAAGGTGATGCAAAAACTCTTGTCGAAGGTAACCATGATTATACAGTAAATGGTAATGTCAAATGGTCCGTTAATGGAAACGTTGATATGACTGTAGCTGGCAACTGGTCCGAGACTATGGCTTCAATGAGTTCTATTGCATCCGGACAATATACTATTGATGGTTCGAGGATTGACATTGGCTAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity Molecular function Inferred from Electronic Annotation (UniProt)
GO:0009253 peptidoglycan catabolic process Biological process Inferred from Electronic Annotation (InterPro)
GO:0016998 cell wall macromolecule catabolic process Biological process Inferred from Electronic Annotation (InterPro)
GO:0031640 killing of cells of another organism Biological process Inferred from Electronic Annotation (UniProt)
GO:0042742 defense response to bacterium Biological process Inferred from Electronic Annotation (UniProt)
GO:0098003 viral tail assembly Biological process Inferred from Electronic Annotation (UniProt)
GO:0098025 virus tail, baseplate Cellular component Inferred from Electronic Annotation (UniProt)
GO:0098932 symbiont entry into host cell via disruption of host cell wall peptidoglycan Biological process Inferred from Electronic Annotation (UniProt)
GO:0098994 symbiont entry into host cell via disruption of host cell envelope Biological process Inferred from Electronic Annotation (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 lysozyme
aka muramidase 		D-glucosamine residues in chitodextrins
Hydrolases
Glycosylases
Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds
 match to sequence model evidence used in automatic assertion
ECO:0000256 		HAMAP-Rule:MF_04151

Tertiary structure

No tertiary structures available.