Protein

UniProt accession
A0A0A7HB70 [UniProt]
Protein name
Baseplate central spike protein
PhaLP type
endolysin

evidence: UniProt function annotation

probability: 99 % (predicted by ML model)

Protein sequence
MINMSDNVSWFVGVVEDRMDPLQQGRVRVRVWGMHPYEKVQGPVKGLRTEDLPWMSVLMPTSSASVSGIQTAMTGMVPGTQVYGHFLDKWKLNGLVIGTYGSASRQKANTNEGFADPTGQYPLYLGNDAAALNRGGEVGYDATSNIIQDANTDVGINPDGLDLSQVKPDDNPNFTIENMLHRDEGLRLKVYWDTEGYPTIGIGHLITPQPIRDMNQINKILSNQIGREVKGNPGAISMDEASKLFQEDLKKVQNDIGKHSVVGPVYNKENRSRQMALENMAFQMGLGGLAKFRGMLGAMLIGDYKKAFEEARNSVWFNQTKGRASRVSMIILTGNMESYGIMAPKEREFNGRSYRMIQTFAAPTNSDPADPWTPEDSRILFKEPDSSYKGEYPYVQTMQTEGGHIQEFDNTPGQERYRLIHPTGSYEEVAPDGRKTVKTVADGYYMTQGDSSTYVGGNNKVNVGGDETYYNMANVRRQTDGSESIHIRGNETKTVEGDGTLIVKGNVTVIVEGNADITVKGDAKTLVEGNHDYTVNGNVTWSVNGNVDMTVAGNWSETMSTMSSIASGQYTIDGSRIDIG
Physico‐chemical
properties
protein length:580 AA
molecular weight:63856,00000 Da
isoelectric point:5,21244
aromaticity:0,07931
hydropathy:-0,55379

Domains

Domains [InterPro]
IPR010609
537–559
IPR010609 IPR001165 IPR009590
IPR046397
3–580
IPR046397
IPR023346
132–344
IPR023346
IPR052619
171–338
IPR052619
IPR023347
174–342
IPR023347
IPR002196
183–316
IPR002196
Protein sequence: A0A0A7HB70
1 580
Legend: Pfam SMART CDD TIGRFAM HAMAP SUPFAM PRINTS Gene3D PANTHER Other

Taxonomy

  Name Taxonomy ID Lineage
Phage Escherichia phage vb_EcoM-VR5
[NCBI] 		1567026 Straboviridae > Dhakavirus > Dhakavirus vr5
Host Escherichia coli
[NCBI] 		562 Bacteria > Proteobacteria > Gammaproteobacteria > Enterobacteriales > Enterobacteriaceae > Escherichia

Coding sequence (CDS)

Coding sequence (CDS)
Genbank protein accession
AIZ01937.1 [NCBI]
Genbank nucleotide accession
KP007359 [NCBI]
CDS location
range 74316 -> 76058
strand +
CDS
ATGATTAACATGTCTGATAACGTAAGTTGGTTCGTCGGTGTAGTTGAAGACCGAATGGACCCTCTGCAACAAGGTCGAGTACGTGTACGTGTATGGGGTATGCATCCTTATGAAAAGGTACAGGGTCCTGTAAAGGGCCTTCGTACTGAAGATTTACCCTGGATGTCTGTATTGATGCCTACATCTTCAGCTTCTGTTTCTGGCATCCAGACAGCAATGACTGGCATGGTTCCTGGTACACAGGTTTATGGCCACTTTCTTGATAAGTGGAAATTAAATGGATTAGTAATTGGTACTTACGGCTCTGCTTCAAGACAAAAGGCAAATACAAACGAAGGTTTCGCCGATCCTACAGGACAATATCCACTTTATTTAGGTAATGACGCCGCTGCACTAAACAGAGGTGGTGAAGTTGGATACGACGCCACATCTAATATAATACAAGATGCAAACACCGATGTAGGTATTAATCCTGATGGATTAGACTTAAGCCAAGTCAAGCCTGATGATAATCCTAATTTCACAATAGAAAACATGCTTCATCGTGATGAGGGACTTCGACTTAAGGTATATTGGGACACAGAAGGATATCCTACTATAGGTATAGGCCATCTTATTACTCCACAACCTATTAGAGATATGAATCAGATAAACAAAATATTATCTAATCAAATAGGCCGTGAAGTTAAAGGTAACCCTGGCGCAATATCAATGGACGAAGCTTCTAAGTTATTCCAAGAAGACCTTAAAAAAGTCCAAAACGATATAGGCAAACATAGTGTCGTAGGCCCTGTTTACAATAAAGAAAACCGCTCTAGACAAATGGCTCTTGAAAACATGGCTTTCCAAATGGGCCTAGGCGGACTCGCCAAATTCCGTGGTATGCTCGGTGCAATGCTAATAGGCGATTATAAAAAGGCATTTGAGGAAGCTCGAAATTCGGTATGGTTTAACCAAACTAAGGGCCGCGCATCAAGGGTATCAATGATTATCCTTACAGGTAATATGGAATCATATGGTATTATGGCCCCTAAAGAAAGAGAATTTAACGGGCGTTCATATAGAATGATTCAAACCTTTGCCGCCCCTACAAATTCCGATCCAGCCGATCCATGGACTCCAGAAGATTCAAGGATTCTTTTTAAAGAACCTGATTCTAGCTATAAAGGCGAATATCCTTATGTCCAAACTATGCAAACTGAAGGCGGGCATATTCAAGAATTCGATAACACCCCTGGACAAGAACGTTATCGTTTAATCCACCCTACAGGTAGTTATGAAGAAGTTGCTCCTGATGGACGTAAAACAGTTAAGACCGTAGCCGATGGTTATTATATGACCCAAGGAGATTCTAGTACTTACGTGGGCGGTAATAATAAAGTCAACGTGGGCGGTGACGAAACCTATTACAATATGGCTAACGTGCGACGTCAAACTGACGGTTCTGAAAGCATTCATATTCGTGGTAATGAAACCAAAACAGTAGAAGGCGATGGGACCCTTATTGTTAAAGGAAATGTTACGGTTATTGTTGAAGGCAATGCTGATATAACTGTTAAAGGTGATGCAAAAACTTTAGTTGAAGGCAACCATGATTATACTGTTAATGGAAACGTTACTTGGTCGGTAAATGGAAATGTTGATATGACCGTCGCTGGTAATTGGTCTGAAACTATGTCGACTATGAGTTCTATTGCATCCGGTCAATATACTATTGATGGTTCGAGGATTGACATTGGCTAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity Molecular function Inferred from Electronic Annotation (UniProt)
GO:0009253 peptidoglycan catabolic process Biological process Inferred from Electronic Annotation (InterPro)
GO:0016998 cell wall macromolecule catabolic process Biological process Inferred from Electronic Annotation (InterPro)
GO:0031640 killing of cells of another organism Biological process Inferred from Electronic Annotation (UniProt)
GO:0042742 defense response to bacterium Biological process Inferred from Electronic Annotation (UniProt)
GO:0098003 viral tail assembly Biological process Inferred from Electronic Annotation (UniProt)
GO:0098025 virus tail, baseplate Cellular component Inferred from Electronic Annotation (UniProt)
GO:0098932 symbiont entry into host cell via disruption of host cell wall peptidoglycan Biological process Inferred from Electronic Annotation (UniProt)
GO:0098994 symbiont entry into host cell via disruption of host cell envelope Biological process Inferred from Electronic Annotation (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 lysozyme
aka muramidase 		D-glucosamine residues in chitodextrins
Hydrolases
Glycosylases
Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds
 match to sequence model evidence used in automatic assertion
ECO:0000256 		HAMAP-Rule:MF_04151

Tertiary structure

No tertiary structures available.