Protein

UniProt accession

A0A0A0YP95 [UniProt]

Protein name

Pre-baseplate central spike protein

PhaLP type

endolysin

evidence: UniProt function annotation

probability: 99 % (predicted by ML model)

Protein sequence

MDMISNAVEWFVGVVEDRMDPLKQGRVRVRVIGLHPFQKTQGSISGIPTEDLPWMSVLQPITSASMSGIGGSVTGPVEGTHVYGHWLDKYRTNGLVMGTYGANSKVRPNTTEGFSDPTGQYPRYLGNDTNVLNQGGETGYDSTSNVIQDSNLDTGINPDDTDLSDIPEDNNPDYTIESMLRRDEGLRLKVYWDSEGYPTIGIGHLIVMQNIRDMNQINKILSKQIGREVKGNPGSISMDEASALFTDDLATVQRDIKQNPKVGPVYAKMNKSRKMALENMSFQMGVWGVAKFNNMLQAMFVGDWKKAYNSARDSLWFQQTKGRASRVSMIILTGNMESYGIPVSTGGKKDLSAAAVVRTSTDPSEPPIPNDSRILFKEPVSSYEGQYPYVHTMETESGHIQEFDDTPGYERYRLIHPTGTYEEVAPDGRRTRKTVNDLYDITNGDGNILVSGDKKVNVGANETYYNMADRLHQIDGSNTIFIRGNETKTIEGNGTLLVKGDVKIVVKGNADILVEGDAKTEVQGNHDYTVNGNVKWSVLGNVDMTVAGNWSETMSTMSSKASGQYTIDGSRIDLG

Physico‐chemical properties

protein length:	575 AA
molecular weight:	63346,00000 Da
isoelectric point:	5,14526
aromaticity:	0,07478
hydropathy:	-0,53739

Domains

Domains [InterPro]

IPR002196

183–311

IPR002196 IPR009590 IPR010609

IPR023347

178–342

IPR023347

IPR046397

3–575

IPR046397

IPR023346

130–342

IPR023346

IPR052619

175–338

IPR052619

IPR001165

177–196

IPR001165

Protein sequence: A0A0A0YP95

1 575

Legend: Pfam SMART CDD TIGRFAM HAMAP SUPFAM PRINTS Gene3D PANTHER Other

Domains [InterPro]

InterPro ID	Start	End	Source	Name
IPR002196	183	311	Pfam	Glycoside hydrolase, family 24
IPR023347	178	342	Gene3D	Lysozyme domain superfamily
IPR046397	3	575	HAMAP	Pre-baseplate central spike protein Gp5
IPR023346	130	342	SUPFAM	Lysozyme-like domain superfamily
IPR009590	33	173	Pfam	Protein Gp5, N-terminal OB-fold domain
IPR010609	532	554	Pfam	Gp5, C-terminal
IPR052619	175	338	PANTHER	Bacteriophage lysozyme-like
IPR001165	177	196	PRINTS	T4-type lysozyme

Taxonomy

	Name	Taxonomy ID	Lineage
Phage	Citrobacter phage Moon [NCBI]	1540095	Straboviridae > Moonvirus > Moonvirus moon
Host	Citrobacter freundii [NCBI]	546	Bacteria > Proteobacteria > Gammaproteobacteria > Enterobacteriales > Enterobacteriaceae > Citrobacter

Coding sequence (CDS)

Genbank protein accession

AIX12139.1 [NCBI]

Genbank nucleotide accession

KM236240 [NCBI]

CDS location

range 78175 -> 79902
strand +

CDS

ATGGATATGATTAGTAATGCAGTAGAATGGTTCGTCGGTGTAGTTGAAGATAGAATGGACCCTCTTAAACAAGGGCGTGTGCGTGTGCGTGTAATTGGATTACATCCATTTCAAAAGACTCAAGGATCTATTTCTGGTATCCCTACTGAAGATCTTCCATGGATGAGTGTTCTTCAACCAATTACTTCTGCCTCAATGTCTGGTATAGGCGGTTCAGTTACTGGCCCAGTTGAAGGTACTCACGTATATGGTCATTGGTTGGACAAATATCGAACAAACGGTTTAGTGATGGGTACTTATGGAGCTAATTCTAAAGTTAGACCTAACACTACTGAAGGATTTTCTGATCCAACTGGACAATATCCTCGGTATCTTGGCAACGACACTAACGTATTGAACCAAGGCGGAGAGACCGGTTATGATTCAACAAGTAACGTAATACAAGATTCAAACCTCGACACTGGTATTAATCCAGATGACACAGATCTATCAGATATTCCAGAAGACAATAACCCTGACTATACGATTGAGTCAATGCTTCGTCGTGATGAAGGTCTTCGTTTGAAGGTTTACTGGGACTCCGAAGGATATCCGACAATTGGTATTGGTCACCTCATCGTGATGCAAAATATTCGTGACATGAATCAGATCAACAAGATTCTGTCTAAACAAATTGGTCGAGAAGTAAAGGGTAATCCTGGCTCTATTTCAATGGATGAGGCATCAGCTTTATTCACTGATGACTTAGCAACAGTTCAACGCGATATTAAGCAAAACCCGAAGGTTGGGCCAGTTTATGCCAAGATGAATAAGTCAAGGAAAATGGCTCTTGAAAATATGTCATTCCAAATGGGTGTCTGGGGTGTAGCTAAGTTCAACAATATGCTTCAAGCTATGTTCGTTGGTGATTGGAAAAAAGCATATAACTCTGCTCGAGATTCATTATGGTTTCAACAAACTAAAGGTCGTGCATCTCGTGTTTCGATGATTATCTTGACCGGTAACATGGAGTCATATGGTATTCCGGTAAGCACTGGCGGCAAAAAAGATTTATCGGCCGCGGCGGTAGTTCGTACAAGCACAGACCCAAGTGAGCCACCAATCCCGAATGACTCTCGCATTCTTTTTAAAGAGCCAGTATCTTCATATGAGGGTCAATATCCTTATGTGCATACGATGGAAACTGAGTCAGGACATATTCAAGAATTTGATGATACTCCTGGATATGAGCGTTATCGTTTAATTCATCCAACTGGAACTTATGAAGAAGTTGCACCTGATGGTAGACGTACTCGTAAAACAGTAAATGATCTTTACGATATCACAAACGGTGACGGTAATATTTTAGTATCGGGCGATAAGAAAGTTAACGTCGGTGCTAATGAAACTTATTACAACATGGCTGATCGCCTTCATCAGATTGATGGTTCAAACACAATCTTTATTCGTGGAAATGAAACCAAGACGATAGAAGGTAATGGAACTCTTTTAGTCAAAGGCGATGTAAAAATTGTGGTTAAAGGAAATGCAGATATTTTAGTCGAGGGTGATGCCAAAACTGAAGTTCAAGGCAATCACGATTACACTGTAAATGGAAACGTCAAATGGTCTGTCCTTGGTAATGTGGACATGACTGTTGCTGGTAATTGGTCAGAAACAATGAGCACAATGAGTTCTAAAGCTTCTGGACAATACACTATTGATGGTTCACGTATAGATCTAGGCTAA

Gene Ontology

	Description	Category	Evidence (source)
GO:0003796	lysozyme activity	Molecular function	Inferred from Electronic Annotation (UniProt)
GO:0009253	peptidoglycan catabolic process	Biological process	Inferred from Electronic Annotation (InterPro)
GO:0016998	cell wall macromolecule catabolic process	Biological process	Inferred from Electronic Annotation (InterPro)
GO:0031640	killing of cells of another organism	Biological process	Inferred from Electronic Annotation (UniProt)
GO:0042742	defense response to bacterium	Biological process	Inferred from Electronic Annotation (UniProt)
GO:0098003	viral tail assembly	Biological process	Inferred from Electronic Annotation (UniProt)
GO:0098025	virus tail, baseplate	Cellular component	Inferred from Electronic Annotation (UniProt)
GO:0098932	symbiont entry into host cell via disruption of host cell wall peptidoglycan	Biological process	Inferred from Electronic Annotation (UniProt)
GO:0098994	symbiont entry into host cell via disruption of host cell envelope	Biological process	Inferred from Electronic Annotation (UniProt)

Enzymatic activity

EC Number	Entry Name	Reaction Catalyzed	Classification	Evidence	Source
3.2.1.17	lysozyme aka muramidase	D-glucosamine residues in chitodextrins	Hydrolases Glycosylases Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds	match to sequence model evidence used in automatic assertion ECO:0000256	HAMAP-Rule:MF_04151

Tertiary structure

No tertiary structures available.