Protein

Protein accession
R4VJX1 [UniProt]
Representative
7UWnF
Source
UniProt (cluster: phalp2_40086)
Protein name
Uncharacterized protein
Lysin probability
100%
PhaLP type
endolysin
Probability: 93% (predicted by ML model)
Protein sequence
MPNDVVESLLQEDIAEAEQQAKAVIAARAGEAGWKRMSKANKALATELAFNVGPGNFRRYSEFMRLATSSDPEEQKKAASEIGRTYVDPKTNRKIPLSDRVQKIIDSVS
Physico‐chemical
properties
protein length:109 AA
molecular weight:12038,5 Da
isoelectric point:7,97
hydropathy:-0,60
Representative Protein Details
Accession
7UWnF
Protein name
7UWnF
Sequence length
174 AA
Molecular weight
19946,22210 Da
Isoelectric point
5,81420
Sequence
MRATEHEPAFLAYIKRVEGGEEHRDDETGHWFSYYAPEGNETIGYGHVVLPHERDVSWLWVTGLSDLQVETLLKQDLTIARFGAKDAAGASHWGELSALQQQMLIDFSFNLGPGFYKTFPKFLRCVLEGDIEGALKESKRFYFDPRSRAFKELKHRNRCFEEFVRAALAAKEAS
Other Proteins in cluster: phalp2_40086
Total (incl. this protein): 13 Avg length: 168,5 Avg pI: 7,45
Protein ID Length (AA) pI
7UWnF 174 5,81420
22Fwd 205 4,75370
3GypH 203 5,61742
40Rk2 183 9,21816
4ihkW 217 9,61012
8EdVV 203 5,76503
8sptO 183 9,32595
8wYwK 183 9,32595
8wzRA 203 5,61742
R9RFC7 109 7,96573
R9RGF0 109 7,96573
R9RGV3 109 7,96573
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_27983
XBT4
 216 42,3% 156 3.050E-32
2 phalp2_9437
pkYK
 27 31,7% 129 3.770E-17
3 phalp2_34888
4fNjG
 27 33,3% 114 3.326E-16
4 phalp2_35544
YW2Y
 3 32,7% 159 4.539E-16
5 phalp2_21123
AWqg
 1 32,5% 178 4.769E-14
6 phalp2_1386
1iVBH
 20 28,3% 113 6.500E-14
7 phalp2_16776
183kM
 1 28,0% 157 6.500E-14
8 phalp2_32005
5iHOn
 21 31,3% 137 5.670E-13
9 phalp2_17008
8jNgs
 3526 30,7% 117 3.618E-12
10 phalp2_27968
RI1z
 5083 32,4% 111 1.242E-11

Domains

Domains [InterPro]
GH24
Representative sequence (used for alignment): 7UWnF (174 AA)
Member sequence: R4VJX1 (109 AA)
1 174 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF00959

Taxonomy

  Name Taxonomy ID Lineage
Phage Alteromonas phage vB_AmaP_AD45-P1
[NCBI] 		1300004 No lineage information
Host Alteromonas macleodii str. 'Balearic Sea AD45'
[NCBI] 		1004787 Proteobacteria > Gammaproteobacteria > Alteromonadales > Alteromonadaceae > Alteromonas >

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
KF005317 [NCBI]
CDS location
range 102405 -> 102734
strand -
CDS
GTGCCTAACGATGTAGTCGAGAGCTTATTGCAAGAAGATATTGCAGAAGCCGAACAACAGGCTAAGGCAGTTATCGCTGCTCGTGCAGGAGAGGCTGGCTGGAAAAGAATGTCTAAAGCAAATAAAGCTTTAGCAACAGAGCTTGCTTTTAATGTAGGGCCTGGTAATTTTAGGAGGTACTCGGAGTTTATGCGTTTAGCTACCAGCTCTGATCCAGAAGAACAGAAAAAGGCTGCTTCTGAGATAGGGAGGACTTACGTTGACCCTAAAACAAACCGGAAGATACCTTTATCTGACAGAGTACAAAAAATTATAGACAGTGTAAGCTAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
upi0003334fd9_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (7UWnF) rather than this protein.
PDB ID
7UWnF
Method AlphaFoldv2
Resolution 90.85
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50