Protein

Protein accession
D6QWP3 [UniProt]
Representative
72wI1
Source
UniProt (cluster: phalp2_35303)
Protein name
PlyM29
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MKILIDAGHGPNTPGKRSPDGMREFEFNSRAADVMKAELEEYEGVTVYFAHEPKRDVPLKERTDNANKLCVDLFFSIHANANTGKMGDWGGIDSFVYTSNPKEARKLADIVQRNLIAATKLRNRGVKTADFHVLRETHMTAILVEHGFMDSKTDLPYLKSDAYRKLCAESNVKSIAQMYGLKRKPAPKPVVKPAVSSDVFYRVVTGSFGDRDNAGRRLAELKKAGFDSFIDVYKK
Physico‐chemical
properties
protein length:235 AA
molecular weight:26333,8 Da
isoelectric point:9,34
hydropathy:-0,51
Representative Protein Details
Accession
72wI1
Protein name
72wI1
Sequence length
293 AA
Molecular weight
31904,55110 Da
Isoelectric point
6,67531
Sequence
LKLILVYKKGDDSINHLKIALDAGHGPDTPGKRTPDGSMREFQFNSAVARYAAELLAQCPGVQTLFTHAADGSRDVPLKERTDRANSWGADLLVSIHANASGDGWSNAEGIETFTYSVPSAASTRLAQTIQSALIASTGLRDRGVKIANFHMVRESKMPSVLLECGFMTNQQEAELLKSDAYRRKCATAIVSGIAKACNFHVPSQPEFNIPDKPATQIPQNPVPNPDNSSKKTEFSDVNAGSWYESAIQRISSSEIGLMSGYPDGTFKPDERVTRGELAVILTRLLNREVKQE
Other Proteins in cluster: phalp2_35303
Total (incl. this protein): 17 Avg length: 278,1 Avg pI: 8,51
Protein ID Length (AA) pI
72wI1 293 6,67531
3PcuT 299 9,31280
4LMJO 280 8,68552
4Li2S 284 6,83724
4LrsA 292 9,02056
4MzUu 282 8,27556
4lGdv 261 9,55752
6T6VF 285 9,63346
6TeEq 285 9,69503
6b8l4 271 6,60108
7cnoA 241 9,17122
7xAL9 360 8,62737
81fZZ 289 8,95764
CFt4 264 9,12816
bhFh 270 5,48646
D6QWP2 236 9,62199
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_23918
1NTlO
 42 45,4% 209 1.033E-61
2 phalp2_355
72B21
 34 36,9% 192 2.570E-58
3 phalp2_13925
foQI
 206 50,2% 189 9.742E-56
4 phalp2_32087
63Erl
 43 42,7% 199 1.137E-51
5 phalp2_37291
81fVt
 2 34,2% 190 2.125E-41
6 phalp2_31486
3PO9t
 18 37,9% 211 4.725E-40
7 phalp2_7949
zu48
 832 42,1% 185 6.443E-40
8 phalp2_27233
3PKbz
 18 40,7% 184 1.633E-39
9 phalp2_38987
84xdy
 117 36,0% 186 2.652E-38
10 phalp2_24413
4m1OU
 1246 39,7% 196 6.714E-38

Domains

Domains [InterPro]
Ami3
SLH
Representative sequence (used for alignment): 72wI1 (293 AA)
Member sequence: D6QWP3 (235 AA)
1 293 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF00395, PF01520

Taxonomy

  Name Taxonomy ID Lineage
Phage uncultured phage
[NCBI] 		278008 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
HM011617 [NCBI]
CDS location
range 1 -> 708
strand +
CDS
ATGAAAATATTAATCGATGCCGGCCACGGACCAAACACGCCAGGCAAACGGAGTCCTGACGGAATGCGCGAATTCGAATTTAATAGCCGAGCTGCTGACGTCATGAAGGCGGAGCTTGAAGAATACGAGGGTGTGACGGTCTACTTTGCGCATGAGCCTAAGCGCGATGTGCCGTTGAAAGAGCGGACTGACAACGCGAACAAACTTTGCGTCGACCTATTCTTCAGTATTCACGCGAACGCTAACACCGGCAAGATGGGCGACTGGGGCGGAATTGATTCGTTCGTCTATACGTCCAATCCGAAGGAAGCACGGAAGCTGGCCGACATTGTGCAGCGCAATCTAATCGCGGCTACTAAACTTCGTAATCGCGGCGTCAAGACGGCCGACTTTCACGTACTGCGCGAAACGCACATGACGGCAATCCTCGTCGAGCACGGCTTTATGGATTCGAAGACAGACTTGCCGTACTTGAAGTCGGATGCCTATCGCAAGCTTTGCGCTGAGTCTAACGTAAAGTCAATCGCGCAAATGTACGGACTCAAGCGCAAGCCTGCGCCGAAGCCCGTGGTCAAGCCAGCCGTCAGCTCCGACGTATTCTATCGCGTTGTGACCGGTTCATTTGGCGACAGGGATAACGCCGGACGACGCCTGGCTGAGCTGAAAAAGGCCGGCTTTGATTCGTTCATTGACGTTTATAAAAAGTAA

Gene Ontology

Description Category Evidence (source)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042834 peptidoglycan binding molecular function None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
upi0001d1d782_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (72wI1) rather than this protein.
PDB ID
72wI1
Method AlphaFoldv2
Resolution 84.68
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50