Protein

Protein accession
D6QWN6 [UniProt]
Representative
3zJio
Source
UniProt (cluster: phalp2_14292)
Protein name
PlyM22
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MARAKGLSRNMAAFLDMIGWSEIGDKLLAVSDDGYNVIVGSTPTKPKLFDDYAAHPQIYVKSVNSTAAGRYQILGKYATHYMAQLKLPDFAPASQDKIAIQLIRECKAVQLIEDGHIGRAITACKSRWASFEGAGYGQREHSIDDLISHFIAYGGVLAK
Physico‐chemical
properties
protein length:159 AA
molecular weight:17378,7 Da
isoelectric point:8,49
hydropathy:-0,11
Representative Protein Details
Accession
3zJio
Protein name
3zJio
Sequence length
167 AA
Molecular weight
17904,83340 Da
Isoelectric point
5,26871
Sequence
VTRFAFPAGLAGAQSSAFLNMTAISEIGPALLANSDDGYNVLVGSTAQHPILFSDYSQHPHILNHSLDSTAAGRYQFIWPTWQSAAKALGLTDFSPESQDRACVWLLQQCGAYLPLIQGDFDAAVMHASTQWASLPGSKAGQHVNSWIALYDVFTKDGGVSLCTEKS
Other Proteins in cluster: phalp2_14292
Total (incl. this protein): 170 Avg length: 164,5 Avg pI: 7,88
Protein ID Length (AA) pI
3zJio 167 5,26871
16fRT 163 8,76243
1Ih9c 167 6,56942
1d5NT 166 6,89567
1fwr8 170 6,17990
1hSlv 164 9,74415
1hkmb 164 9,68987
1jWyp 164 9,34136
1lJRK 153 6,17024
1lNVu 181 6,05883
1oppt 164 5,38933
1ox3E 166 6,99457
1ox5Q 160 5,20238
1qlSE 159 9,48390
258I0 164 5,38387
28z2J 164 5,90753
2AXU3 164 9,41053
2HTWV 171 9,23318
2SKU4 162 5,20636
2SdNz 162 5,20636
2Sqb8 151 5,35391
2WS65 164 8,02356
2Y84d 164 9,39067
2aDHd 164 9,34284
2sAF8 153 6,57823
2sRQc 152 7,73104
31Udb 235 5,10030
35LR4 171 9,25381
35W1h 159 5,45662
3Ax9Z 153 4,79740
3Llqd 164 5,88309
3OoJv 227 4,98031
3aLuj 153 6,19439
3f4Ow 157 4,80587
3xCqV 158 7,79927
4DZUn 175 6,69253
4FblP 169 5,75696
4I251 172 5,08342
4K1Vp 157 5,07785
4KM38 185 7,60173
4KUtv 158 4,54203
4ONee 154 5,19221
4PxuO 185 8,78364
4dNHX 151 5,90684
4dSDK 140 5,50124
4wdr6 178 6,28562
5BBCq 174 5,93646
5BCxR 167 5,92634
5BEIX 166 9,56525
5Bd6x 118 5,03039
5F5w1 165 6,03911
5tgpd 174 5,62759
5yNsM 167 6,45665
5z0af 166 6,27658
5z1DQ 166 6,50024
5z33Z 164 9,39080
6HwWM 158 5,54256
6Lf6I 174 5,80095
6Mvb9 164 9,11320
6NsLT 162 5,55507
6QQry 159 6,88595
6RXWc 155 8,53215
6SSLG 163 7,67465
6STrj 164 8,73187
6Sdg0 164 9,34149
6SjuA 166 9,56448
6Txa2 179 5,82034
6XKK0 164 7,01361
6XTY3 164 5,56274
6Y1HF 153 5,91094
6Y4PB 166 6,94626
740WP 164 9,56525
740YM 164 9,39080
740Zu 164 9,39080
78OYh 164 9,74596
7ATp6 150 9,00187
7Bdpe 166 9,29655
7PsPX 164 9,16355
7RrQh 164 9,56525
7c5CB 164 9,68910
7cK4l 171 5,80090
7dgvl 164 9,39080
7dp0W 164 9,74506
7elcj 164 9,00045
7f4pW 164 9,56525
7hWvQ 164 9,56525
7iTrp 164 9,34090
7kSZB 164 9,56525
7lF4G 165 8,88047
7lOlR 164 9,68910
7nNBJ 164 9,34090
7nNN6 164 9,34149
7nNSQ 164 9,45637
7nNfB 164 9,62063
7nNvz 164 9,34090
7nNzk 164 9,74506
7nOFT 164 9,51607
7nOwv 164 9,74602
7nP2d 164 9,34078
7nPnK 164 9,39016
7nPtU 164 9,80695
7nPxv 164 9,34090
7nQ11 164 9,00051
7nQbd 164 9,04448
7nQkX 163 9,34149
7px4H 164 9,34071
7pxB7 164 9,68910
7pxcK 164 8,96015
7pxhz 164 9,00000
7pxiQ 164 9,39080
7pxlK 164 9,56525
7qKMN 163 9,00141
7qL54 163 9,00141
7qLNF 163 9,00141
7qLaU 163 9,34207
7qM12 164 9,34078
7qM1U 163 8,04000
7qMD4 164 9,34090
7qMIL 163 9,00141
7qMiR 163 9,34207
7qMwZ 163 9,00141
7qN5o 163 9,29720
7qNLp 163 8,04000
7qWCA 164 8,00377
7r4SE 164 9,16355
7r4WH 166 9,00135
7r5Cz 164 9,39003
7r5ju 164 9,04448
7r5sb 164 9,62063
7r65q 164 9,20210
7r68o 164 9,39080
7r69W 164 9,44638
7r6cg 164 9,34090
7r7Ik 164 9,68987
7u3zK 164 9,29591
7vPVF 142 9,39396
7vdmm 150 7,08011
7wLjF 164 9,56525
7wLji 164 9,62063
7xKLD 159 9,56693
7xKt5 164 9,68910
7xoE9 164 9,34078
7xoOX 164 8,04425
7yhDz 164 9,34071
7yhGP 164 9,34071
7yhfa 145 8,04000
7z53C 142 9,34471
7z54t 164 9,62063
7z56T 164 8,04399
7zdqG 164 9,56525
8218e 225 4,94587
86ZEx 163 6,19655
86ZTl 167 5,27872
86Zaj 159 6,01279
86mJX 153 5,72297
871FC 161 5,74366
871SR 159 5,93146
874uf 153 4,63217
87Yk4 175 5,15396
8i6I3 154 5,88746
8rTaU 234 5,04801
S3Qt 160 7,00998
YoLZ 180 6,28062
ZsYX 169 9,25974
bnE0 164 6,95183
fMoE 151 6,01598
gCAu 169 9,38739
gTX2 164 9,68910
hrfv 167 5,67909
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_8549
1DMQs
 2433 40,9% 166 4.226E-61
2 phalp2_14090
8oyxl
 17 43,0% 151 1.492E-60
3 phalp2_15310
1iZB6
 260 42,7% 159 2.110E-57
4 phalp2_22274
7tL4I
 47 37,5% 165 7.450E-57
5 phalp2_4748
7I1R1
 83 36,3% 157 1.311E-52
6 phalp2_34051
89Glt
 18 38,1% 165 9.619E-40
7 phalp2_10185
wALc
 11 35,2% 156 3.814E-37
8 phalp2_29942
8nkTU
 3 35,0% 160 8.879E-36
9 phalp2_32587
1KJKQ
 2 37,3% 126 1.216E-35
10 phalp2_25045
15ncl
 14 32,4% 157 9.116E-27

Domains

Domains [InterPro]
Unannotated
Representative sequence (used for alignment): 3zJio (167 AA)
Member sequence: D6QWN6 (159 AA)
1 167 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage uncultured phage
[NCBI] 		278008 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
HM011610 [NCBI]
CDS location
range 1 -> 480
strand +
CDS
ATGGCGCGCGCAAAAGGCTTGAGTCGCAACATGGCTGCATTCTTGGATATGATTGGTTGGTCTGAGATTGGCGATAAATTGTTGGCAGTGTCCGACGATGGGTATAACGTTATCGTTGGCTCCACCCCCACCAAACCAAAGCTGTTTGACGACTACGCCGCTCATCCGCAAATTTATGTGAAGTCGGTTAACTCGACCGCTGCGGGCAGATATCAGATTCTCGGTAAGTACGCAACTCATTACATGGCCCAACTCAAGTTGCCTGATTTTGCCCCTGCATCACAAGACAAAATTGCAATTCAATTGATCCGCGAATGCAAGGCGGTCCAGTTGATTGAAGATGGCCACATTGGTCGAGCAATCACTGCTTGCAAAAGCCGCTGGGCGAGTTTTGAGGGTGCCGGGTACGGCCAACGTGAGCACTCTATTGATGATTTGATTTCCCATTTCATTGCGTATGGTGGAGTTCTTGCAAAATGA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0044659 viral release from host cell by cytolysis biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
upi0001d1d77b_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (3zJio) rather than this protein.
PDB ID
3zJio
Method AlphaFoldv2
Resolution 92.29
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50