Protein

Protein accession
D6QWM8 [UniProt]
Representative
7sfyx
Source
UniProt (cluster: phalp2_9307)
Protein name
PlyM14
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MTKIIAIDAGHGLNTPGKRTPDNEREWSFNNKVTLAAIKYLNDYEGVKIVRLDDPTGKSDVPLKARTDKANKAKADVLVSIHHNALTGKWGTHGGTEVFTYLGNWPDAERLAKLVLDRILKAYGLKSRGLKKANFHMVRESAMPAILIEGGFMDSTVDIKKMRDDKVLDEAGKAIAEALAVYFGLKKKKPAAPSKLYRVQIGAYSVKANADAQAAKAKRAGYSPYIAREGGLYKVQIGAYSVKANADKMASELKRKGFNVYIA
Physico‐chemical
properties
protein length:263 AA
molecular weight:28798,0 Da
isoelectric point:9,78
hydropathy:-0,38
Representative Protein Details
Accession
7sfyx
Protein name
7sfyx
Sequence length
306 AA
Molecular weight
32982,80110 Da
Isoelectric point
7,10319
Sequence
MAKIAIGAGHGMHTPGKRSPAGEREWSFNNKVVSAAIKYLNRYANTTVIRMDDPTGDTDVPLTTRTNVANNANADILISYHHNANTGQWGSWTGTETYYYPGSSSGLALARAIHPSIVGAMGLRDRGIKSANFHMLRESSMPAILIEGGFMDSTVDIVKMRNNTTMDLTGKALAEAIAANLGLQPEGGGTTYTVKAGDTLWGIAQAHSMTVSKLQALNNLTDDGIYPGQVLVISGSPSGSASFVEVITASLWVYNAPDWDAKYEIVHQGEVFTVNDVLYVNGSKMYKLKSGLYITGNSNYVRYFSK
Other Proteins in cluster: phalp2_9307
Total (incl. this protein): 22 Avg length: 310,6 Avg pI: 8,77
Protein ID Length (AA) pI
7sfyx 306 7,10319
1c1ux 294 9,60103
2G2wE 291 9,44496
2G2xy 276 9,31512
2G5Kp 351 9,57396
5i2ej 372 9,16678
75tbm 256 8,82754
79eOJ 271 9,89288
7gCCy 306 6,44301
7lBt2 363 9,81101
7qyMN 306 6,44170
7sB4x 256 9,42787
7snvK 306 6,70742
7szd0 306 6,44164
7vQ5C 310 8,51687
7y8KS 381 9,83570
81fIj 370 8,53041
8LF9V 271 9,67266
CFR8 354 9,45488
aXjp 348 9,50337
buN4 276 9,35921
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_23918
1NTlO
 42 52,8% 208 3.068E-72
2 phalp2_35303
72wI1
 17 41,1% 187 2.574E-54
3 phalp2_15036
7cnpE
 7 29,5% 322 2.951E-50
4 phalp2_11491
tx2m
 34 28,9% 363 7.032E-47
5 phalp2_24413
4m1OU
 1246 36,8% 209 5.440E-45
6 phalp2_37291
81fVt
 2 36,3% 187 3.324E-39
7 phalp2_31486
3PO9t
 18 37,0% 205 4.529E-39
8 phalp2_26616
7oxe5
 7 38,9% 185 3.488E-35
9 phalp2_2704
7cWsF
 33 29,4% 190 2.590E-33
10 phalp2_6374
7yZe6
 41 32,3% 201 7.593E-32

Domains

Domains [InterPro]
Ami3
LysM
DUF5776
Representative sequence (used for alignment): 7sfyx (306 AA)
Member sequence: D6QWM8 (263 AA)
1 306 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01476, PF01520, PF19087

Taxonomy

  Name Taxonomy ID Lineage
Phage uncultured phage
[NCBI] 		278008 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
HM011602 [NCBI]
CDS location
range 1 -> 792
strand +
CDS
ATGACGAAGATAATCGCTATCGACGCTGGCCACGGACTTAATACTCCGGGCAAACGTACGCCGGATAATGAGCGCGAATGGTCGTTTAATAATAAGGTCACACTAGCCGCGATTAAGTATTTGAACGATTATGAAGGCGTTAAAATCGTAAGACTCGACGATCCGACCGGTAAATCGGACGTACCTTTAAAAGCGCGCACCGACAAGGCGAATAAGGCGAAGGCTGACGTACTAGTGTCGATTCATCATAATGCGCTCACGGGCAAGTGGGGAACGCACGGCGGTACGGAAGTATTTACGTATCTCGGAAACTGGCCGGACGCGGAAAGGCTGGCGAAGTTAGTACTCGATCGTATCCTAAAAGCTTACGGATTAAAGAGTCGCGGACTAAAGAAGGCTAACTTCCACATGGTACGCGAGAGCGCTATGCCTGCGATATTAATCGAAGGAGGCTTCATGGACTCGACCGTCGATATTAAGAAGATGCGCGACGATAAAGTCCTCGATGAAGCCGGCAAAGCTATCGCGGAAGCACTGGCGGTCTACTTCGGATTAAAGAAGAAGAAACCCGCAGCACCTTCGAAACTGTATCGCGTACAAATCGGAGCTTATTCGGTAAAAGCGAACGCTGACGCACAAGCTGCGAAAGCTAAACGCGCAGGCTATTCGCCATATATCGCACGCGAAGGCGGACTTTACAAAGTTCAAATCGGAGCTTATTCCGTCAAAGCGAACGCCGATAAAATGGCATCGGAATTGAAGCGCAAAGGCTTCAACGTATATATTGCGTAA

Gene Ontology

Description Category Evidence (source)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042834 peptidoglycan binding molecular function None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
upi0001d1d767_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (7sfyx) rather than this protein.
PDB ID
7sfyx
Method AlphaFoldv2
Resolution 93.43
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50