Protein

Protein accession
D6QWM7 [UniProt]
Representative
aPPg
Source
UniProt (cluster: phalp2_36282)
Protein name
PlyM13
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MAKRKVYIDLGHEGDGKGMDPGAVANGLKEANVVLEIGKYMKDMFANYENVEVKFSRLANKNLSLNQRTNEANAWGADVLCSIHINAGGGKGFESFIYPGAGSATQAFQNAVHAKIMGTGVFTTDRGKKKANFHMLRESKMTAILTENGFIDNGTDAATLKNRAKLIAIASGHVEGVASFLNLKKKPVSKPEPKPSGKLYKVQVGAFSDRKNADNLAAELKKIGYSTYIVHE
Physico‐chemical
properties
protein length:232 AA
molecular weight:25066,4 Da
isoelectric point:9,52
hydropathy:-0,37
Representative Protein Details
Accession
aPPg
Protein name
aPPg
Sequence length
294 AA
Molecular weight
32916,28940 Da
Isoelectric point
10,08842
Sequence
AMLQNLYNAIVKHNKLKGNRSSPLNDTNFQVLRQTKMAAALIENGFMDSRTDVPIILSDAHARKTAEGIVEFVVEHFKLKKKPVSPNKPVDKEGLIRVQVGAFRNLEYARNLEKDLIKKGYSTYIIQADDGLYKVQTGAYKNRKNAEELVKRLESDGFNTFLTSAAGKAVPDKTQPTKPPAPQRRQIKVDGSWGRDTTRALQEYFNSTVDGIISGQYSNNITRAIIGVSFANKRGSTVIRLLQKHIGARVDGHIGPETVRALQRYLKTPVDGVISRPNSLMVRELQRRLNNGTF
Other Proteins in cluster: phalp2_36282
Total (incl. this protein): 2 Avg length: 263,0 Avg pI: 9,80
Protein ID Length (AA) pI
aPPg 294 10,08842
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_1815
3e8ux
 11 37,2% 282 9.065E-40
2 phalp2_20638
4NMLJ
 3 33,8% 275 6.278E-27
3 phalp2_28871
5hUC8
 21 25,4% 251 2.573E-05
4 phalp2_22102
65fHc
 3 21,8% 270 6.038E-05

Domains

Domains [InterPro]
Ami3
SPOR
Unannotated
Representative sequence (used for alignment): aPPg (294 AA)
Member sequence: D6QWM7 (232 AA)
1 294 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01520, PF05036

Taxonomy

  Name Taxonomy ID Lineage
Phage uncultured phage
[NCBI] 		278008 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
HM011601 [NCBI]
CDS location
range 1 -> 699
strand +
CDS
ATGGCGAAAAGGAAAGTATATATTGATTTAGGGCACGAAGGCGACGGAAAGGGAATGGATCCTGGAGCAGTTGCCAATGGGTTGAAAGAAGCTAATGTTGTTTTAGAGATTGGGAAGTATATGAAAGATATGTTTGCCAACTATGAGAATGTAGAAGTGAAGTTTTCAAGATTGGCAAATAAAAATCTTTCTTTAAATCAGCGCACGAATGAAGCTAATGCCTGGGGTGCTGATGTTCTCTGTTCAATCCATATTAATGCAGGCGGCGGTAAAGGGTTTGAATCCTTCATATATCCAGGTGCAGGATCAGCAACGCAGGCTTTCCAAAATGCTGTTCATGCCAAGATTATGGGAACAGGGGTATTCACGACAGACAGAGGGAAGAAAAAGGCGAATTTCCATATGTTAAGAGAATCTAAAATGACCGCAATCTTAACCGAAAATGGGTTCATTGATAACGGTACAGACGCAGCAACTTTGAAAAACAGAGCAAAGTTAATCGCTATAGCTTCAGGTCATGTGGAGGGAGTAGCTTCTTTCCTTAACCTTAAAAAGAAACCTGTTTCTAAACCAGAGCCGAAACCATCTGGTAAGTTATACAAAGTTCAAGTAGGTGCTTTCTCTGACCGAAAGAACGCTGACAACTTAGCTGCTGAACTAAAGAAAATAGGCTATTCAACTTATATTGTTCACGAATAA

Gene Ontology

Description Category Evidence (source)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042834 peptidoglycan binding molecular function None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
upi0001d1d766_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (aPPg) rather than this protein.
PDB ID
aPPg
Method AlphaFoldv2
Resolution 85.03
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50