Protein

Protein accession
A0AAX4RAL1 [UniProt]
Representative
8INhm
Source
UniProt (cluster: phalp2_26201)
Protein name
Lysin A N-acetylmuramoyl-L-alanine amidase domain protein
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MSQIVDLTGTAIGRGGTQGMWNSAAPTGQLIVIHDTESWTDSAALNWMRSQQNGSYHRLYGLDGKTTVMVPYHRQSWSAMTTGNRIGYHLCATGYASWRLALRRRLARAGSAPKLYDGICSAPATSRRRSGSTRWADYPQMLDAMARDIAELSVAKNIPLIWLTPAQIRAGHKGLCGHAEISKAFGETDHTDPGTGFPRTDVIGRARRRVNPNLLGMTDPELDEFTTLMRQLGES
Physico‐chemical
properties
protein length:235 AA
molecular weight:25846,0 Da
isoelectric point:9,61
hydropathy:-0,43
Representative Protein Details
Accession
8INhm
Protein name
8INhm
Sequence length
242 AA
Molecular weight
26211,42610 Da
Isoelectric point
8,82471
Sequence
MTVHKDLTGISIPKGGTSGMWNAANTIKQVIVIHDTESGNAAGALNWMRSQQNGSYHILVDTDGDSFRMVPDSRQAWAAAATGNRIGLHVCATGYASWRLKMLSKLQSDPKPATMAGRVDNPKDGICTDTGSRRASTVRWADHPAMLEIIAQNVAQWSVTYNIPLRILNAEQVRAGLKGICGHNEISLAFRQTDHTDPGVNFPKTRIVARAIEIVSEKANLLGLTDSELAEVARNFNQLGPA
Other Proteins in cluster: phalp2_26201
Total (incl. this protein): 9 Avg length: 237,4 Avg pI: 9,50
Protein ID Length (AA) pI
8INhm 242 8,82471
A0A0K0N6L7 242 8,82471
A0A5C1K6I5 236 9,74093
A0A5Q2F828 241 9,79779
A0A650FB08 236 9,74093
A0A977KN31 235 9,65873
A0A9E7TRR3 235 9,65873
A0AAE7SM27 235 9,65873
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_32230
7h6JD
 19 40,3% 191 9.490E-42
2 phalp2_30359
4Fho1
 21 32,0% 184 6.309E-22
3 phalp2_22201
6VaYI
 26 31,4% 194 7.353E-21
4 phalp2_11245
6EoH4
 30 28,0% 203 3.335E-18
5 phalp2_33007
4igcZ
 220 30,2% 195 8.324E-18
6 phalp2_16822
1p2ki
 32 28,2% 209 5.170E-17
7 phalp2_31178
7Vvn5
 47 31,4% 207 7.947E-16
8 phalp2_15736
3ndEo
 2 29,6% 182 1.457E-15
9 phalp2_19863
5Bmz6
 51 25,7% 190 8.996E-12
10 phalp2_5045
1p8hV
 9 26,7% 209 1.213E-11

Domains

Domains [InterPro]
Ami2
Representative sequence (used for alignment): 8INhm (242 AA)
Member sequence: A0AAX4RAL1 (235 AA)
1 242 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01510

Taxonomy

  Name Taxonomy ID Lineage
Phage Gordonia phage Morgana
[NCBI] 		3137292 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
PP537962 [NCBI]
CDS location
range 25094 -> 25801
strand +
CDS
ATGAGCCAGATCGTCGACCTCACCGGCACCGCGATCGGTCGCGGCGGCACCCAGGGCATGTGGAATAGCGCCGCGCCGACCGGACAGCTGATCGTCATCCACGACACCGAATCGTGGACCGACTCGGCCGCTCTCAACTGGATGCGGTCTCAGCAAAACGGCAGCTACCACAGGTTGTACGGCCTGGACGGCAAGACCACCGTGATGGTGCCGTACCACCGGCAGTCCTGGTCGGCGATGACGACCGGCAACCGCATCGGGTATCACCTGTGCGCCACTGGCTACGCCTCCTGGCGCCTGGCGCTGCGCCGCCGACTGGCCCGGGCTGGCTCGGCGCCGAAGCTCTACGACGGCATCTGCTCGGCGCCGGCCACCTCGCGCCGCCGCTCCGGCAGCACCCGCTGGGCCGACTACCCGCAGATGCTCGACGCGATGGCCCGCGACATCGCTGAGCTGTCGGTCGCGAAGAACATCCCACTGATCTGGCTCACCCCCGCCCAGATTCGCGCAGGTCACAAGGGTCTGTGCGGGCACGCGGAGATCAGCAAGGCCTTCGGCGAGACCGACCACACCGATCCCGGCACCGGGTTCCCGCGCACCGACGTCATCGGTCGCGCCCGCCGCCGGGTCAACCCGAACTTGCTCGGGATGACCGACCCCGAACTCGACGAGTTCACCACTCTCATGCGCCAGCTCGGCGAGAGCTGA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (8INhm) rather than this protein.
PDB ID
8INhm
Method AlphaFoldv2
Resolution 83.32
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50