Protein

Protein accession
A0AAX4QJZ5 [UniProt]
Representative
4OVfK
Source
UniProt (cluster: phalp2_3620)
Protein name
Lysozyme-like protein
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MAKVTHIVLHYSATYADQNITAADIDKMHKERGWKGIGYHWFIRRDGTVEEGRPESQVGAHVGGQNTGKIGICCAGGLDRGTGPNKGVDNRTPAQISAQIELIRNCLKRYPGAKVVGHRDLAPTQCPGFDVQAWWAQVQKKKQPTPAPVKPDAPVVTPNVSENGFHHVEKGETWFSISQMYDMRLADLLSLNGATEADVLKTGRVLRLKPQKAVPVIPSSEPTGLAAFIALIKKWIGL
Physico‐chemical
properties
protein length:238 AA
molecular weight:25989,5 Da
isoelectric point:9,35
hydropathy:-0,36
Representative Protein Details
Accession
4OVfK
Protein name
4OVfK
Sequence length
314 AA
Molecular weight
33814,27390 Da
Isoelectric point
9,66982
Sequence
MPCRDRKETDMKIDTIVLHYSATYADQNLTVKDIDRMHRDRGWKGVGYHYVIRRDGVVEQGRPENVVGAHVGGQNTGKLGICCIGGLDRATGPNKGVDNRTSAQIESQIRLIKSLLRKYPGARVVGHRDLAPTQCPGFDVRSWWAKVQKKSAPETRPAPATAPAKTAVIGEDKTHVVQKGETWWSISQMHGLGVADFARANGATPADTLVEGRKLSLMIKPNVPKPVEDVVKDAARSGSSSTTNIATGIGAASSTVAIAKEATDAARESVDGVSAILAAGPWVLLLVVALGAGWWIWRERQRKAKMATEAKAAL
Other Proteins in cluster: phalp2_3620
Total (incl. this protein): 7 Avg length: 240,6 Avg pI: 9,02
Protein ID Length (AA) pI
4OVfK 314 9,66982
4OVRq 304 9,78354
IlNg 326 9,75408
A0A0U2BX41 173 10,01705
A0A7G9V0G3 204 6,15927
A0A6J5PD36 125 8,40534
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_36193
72BPm
 409 42,3% 210 2.835E-50
2 phalp2_25557
3CTPR
 25 32,4% 302 5.944E-35
3 phalp2_17895
BC0B
 1 30,0% 356 9.386E-32

Domains

Domains [InterPro]
Ami2
LysM
Disordered region
Representative sequence (used for alignment): 4OVfK (314 AA)
Member sequence: A0AAX4QJZ5 (238 AA)
1 314 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01476, PF01510

Taxonomy

  Name Taxonomy ID Lineage
Phage Microcystis phage Mae-JY35
[NCBI] 		3128143 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
PP438426 [NCBI]
CDS location
range 20686 -> 21402
strand +
CDS
ATGGCGAAAGTCACGCACATCGTCCTGCACTATTCTGCGACCTATGCCGACCAGAACATCACGGCAGCCGACATCGACAAGATGCACAAGGAACGCGGGTGGAAGGGCATCGGCTATCACTGGTTCATTCGCCGCGACGGCACGGTTGAGGAAGGCCGGCCGGAAAGCCAGGTCGGCGCTCACGTCGGCGGGCAGAACACCGGCAAGATCGGCATTTGCTGCGCTGGTGGCCTTGACCGTGGGACCGGCCCGAATAAGGGCGTAGACAACCGGACGCCTGCTCAAATCAGCGCGCAGATCGAACTCATCCGAAACTGCCTGAAGCGATATCCCGGCGCGAAAGTTGTTGGTCACCGCGACCTTGCGCCGACGCAATGCCCCGGCTTCGACGTTCAGGCTTGGTGGGCACAAGTCCAGAAGAAGAAGCAGCCAACGCCGGCCCCGGTCAAACCGGATGCGCCTGTCGTCACACCCAACGTCTCGGAAAACGGCTTTCATCATGTCGAGAAGGGCGAGACGTGGTTTTCCATCTCGCAAATGTACGACATGCGCCTCGCTGACCTCCTGTCACTGAACGGAGCGACCGAGGCCGATGTGCTGAAGACCGGGCGTGTCCTGCGCCTGAAGCCCCAGAAGGCTGTTCCCGTCATCCCGTCGTCCGAGCCGACCGGCCTCGCGGCATTCATCGCCCTCATCAAGAAATGGATTGGCTTATGA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008270 zinc ion binding molecular function None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (4OVfK) rather than this protein.
PDB ID
4OVfK
Method AlphaFoldv2
Resolution 73.46
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50