Protein

Protein accession
A0AAX4QI64 [UniProt]
Representative
1poi7
Source
UniProt (cluster: phalp2_22543)
Protein name
NlpC/P60 family protein
Lysin probability
100%
PhaLP type
endolysin
Probability: 51% (predicted by ML model)
Protein sequence
MPTAQDMVEEARKWVGTPWRHQGRTRVGVDCVGLLVVCARAIGLEVEDRTDYGQSPTNDSLLRHLSSYLTKVHNNQILPGRIGLFTENRFPCHVGIFSDVDGAPHLIHAFARRRMVVEEPFGERSNGFRLIGVFDVSALKE
Physico‐chemical
properties
protein length:141 AA
molecular weight:15840,9 Da
isoelectric point:7,02
hydropathy:-0,24
Representative Protein Details
Accession
1poi7
Protein name
1poi7
Sequence length
59 AA
Molecular weight
6161,02270 Da
Isoelectric point
7,97798
Sequence
MTAEDFVNAGRGWLGVPWRHLGRTRAGVDCIGLVLAAAAKVGMQIADPAPYAREPQGAA
Other Proteins in cluster: phalp2_22543
Total (incl. this protein): 8 Avg length: 88,8 Avg pI: 7,56
Protein ID Length (AA) pI
1poi7 59 7,97798
3NptC 61 9,47339
3R3NT 52 6,23435
4Mmqj 64 8,06127
zZDV 57 8,18782
A0A9E7MQB3 138 6,50701
A0A9E7SUY1 138 7,01407
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_32923
3Igpn
 8 48,2% 56 3.968E-17
2 phalp2_1658
8tBfo
 1 42,8% 49 3.516E-11
3 phalp2_27661
6E3lC
 4 47,5% 40 4.514E-10
4 phalp2_9095
5Ekic
 6 46,3% 41 3.704E-07
5 phalp2_14368
4jLC0
 3 33,3% 54 1.835E-06
6 phalp2_3249
2kUMt
 20 38,2% 47 2.527E-06
7 phalp2_11536
UYfN
 3 38,2% 47 9.097E-06
8 phalp2_20688
4UhO5
 1 37,5% 40 1.727E-05
9 phalp2_34997
4MsPJ
 4 38,3% 60 4.517E-05
10 phalp2_9277
79cFB
 3 36,1% 47 2.246E-04

Domains

Domains [InterPro]
Unannotated
Representative sequence (used for alignment): 1poi7 (59 AA)
Member sequence: A0AAX4QI64 (141 AA)
1 59 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Microcystis phage Mwe-JY26
[NCBI] 		3128149 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
PP438418 [NCBI]
CDS location
range 89263 -> 89688
strand +
CDS
ATGCCCACCGCTCAGGACATGGTGGAAGAGGCTAGGAAGTGGGTGGGGACGCCCTGGCGTCATCAGGGCAGGACTCGTGTCGGCGTGGACTGCGTTGGTCTCCTTGTCGTCTGTGCTCGGGCGATCGGCCTTGAGGTGGAGGATAGGACGGACTACGGACAGAGCCCCACAAACGATAGCCTGCTGCGCCATTTGTCGTCTTACTTGACCAAGGTGCATAACAACCAGATTCTCCCAGGCAGGATCGGGCTGTTCACGGAGAACAGATTCCCTTGCCATGTCGGCATCTTCAGTGATGTCGATGGCGCCCCCCACCTCATCCACGCCTTCGCTCGTCGAAGGATGGTCGTCGAGGAGCCGTTCGGAGAGCGTTCGAATGGTTTCCGTCTGATCGGGGTGTTCGACGTTTCCGCATTGAAGGAGTAG

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008234 cysteine-type peptidase activity molecular function None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (1poi7) rather than this protein.
PDB ID
1poi7
Method AlphaFoldv2
Resolution 93.67
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50