Protein

Protein accession
A0AAX4QGT6 [UniProt]
Representative
4xnnO
Source
UniProt (cluster: phalp2_7367)
Protein name
N-acetylmuramoyl-L-alanine amidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MPQARPQTPTRSVSRIVIHCSDTPDGRPNTVEDIDSWHRERGFRRLDRWRRVMNSKLTSIGYHFVIYVNGAIVTGRSLEEVGAHVQGYNGDSVGVCVIGRGRYSLVQWAALKSNVNALMKKYPEAAVVGHRDLDRRKLCPCFDVRSWVAAGMVAPHEHVLRQEAAP
Physico‐chemical
properties
protein length:166 AA
molecular weight:18688,1 Da
isoelectric point:9,74
hydropathy:-0,39
Representative Protein Details
Accession
4xnnO
Protein name
4xnnO
Sequence length
105 AA
Molecular weight
11785,32340 Da
Isoelectric point
8,93424
Sequence
YHYVIYTDGTAHIGRSIECVGAHCAGYNARSVGICLIGTDKFSTKQWDRLKTLVEKLQEQYTIYRVAGHNEIPRVAKACPGFSVKAWRENEKKALGGYINEVIHA
Other Proteins in cluster: phalp2_7367
Total (incl. this protein): 5 Avg length: 117,6 Avg pI: 8,29
Protein ID Length (AA) pI
4xnnO 105 8,93424
2V9GU 78 5,84017
3btY6 96 8,09866
7HS1M 143 8,82819
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_3887
6RreM
 7260 45,3% 97 3.181E-30
2 phalp2_25112
1plEg
 298 44,5% 92 6.676E-24
3 phalp2_2237
4n15b
 512 44,2% 113 1.725E-23
4 phalp2_11894
2jrH4
 329 41,5% 101 9.675E-21
5 phalp2_10774
3IYDg
 14 38,7% 93 4.708E-20
6 phalp2_24952
kjdf
 441 36,5% 104 3.953E-18
7 phalp2_25435
2NLUL
 9 41,2% 80 3.317E-16
8 phalp2_25442
2RRxP
 189 37,2% 102 2.214E-15
9 phalp2_11611
1k5JO
 2203 33,0% 106 1.352E-13
10 phalp2_1572
7VT79
 79 32,9% 94 2.328E-12

Domains

Domains [InterPro]
Ami2
Representative sequence (used for alignment): 4xnnO (105 AA)
Member sequence: A0AAX4QGT6 (166 AA)
1 105 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01510

Taxonomy

  Name Taxonomy ID Lineage
Phage Microcystis phage Mae-JY22
[NCBI] 		3128138 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
PP438414 [NCBI]
CDS location
range 6680 -> 7180
strand -
CDS
ATGCCGCAAGCCCGTCCACAGACCCCTACGCGATCCGTCTCCCGGATCGTGATCCACTGCTCCGACACGCCTGACGGTCGCCCGAACACCGTCGAGGACATCGACAGCTGGCACCGCGAGCGCGGCTTCCGGCGGCTCGACCGGTGGCGCCGGGTCATGAACTCGAAGCTCACGTCCATCGGGTACCACTTCGTCATCTACGTCAACGGCGCGATCGTCACCGGTCGCTCGCTCGAAGAGGTCGGCGCGCACGTCCAGGGCTACAACGGCGACTCGGTGGGCGTGTGCGTCATCGGGCGTGGCCGCTACTCGCTCGTACAGTGGGCGGCGCTCAAGTCGAACGTCAACGCGCTGATGAAGAAGTACCCGGAGGCGGCCGTCGTGGGTCACCGGGATCTCGATCGCCGAAAGCTGTGCCCTTGCTTCGATGTGCGCTCGTGGGTCGCGGCGGGGATGGTGGCGCCACACGAACACGTTCTCAGACAGGAGGCCGCACCGTGA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008270 zinc ion binding molecular function None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (4xnnO) rather than this protein.
PDB ID
4xnnO
Method AlphaFoldv2
Resolution 93.59
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50