Protein

Protein accession
A0AAX4QGK0 [UniProt]
Representative
7wBZw
Source
UniProt (cluster: phalp2_22282)
Protein name
N-acetylmuramoyl-L-alanine amidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MMNRIVWHHTGGGHLPNDTDRAAYHRLIDGDGRVHAGIHSIEANAPGARLVTGRYAAHTGGLNSGSIGLAVCAMAGGVWANPRASAAFPTPAQIDAVIAETVGLCRTYGIQPVRAHVLSHAEVPLTLGVVQKGKWDFDYQIRKTAGRDPIAIGDELRAEVAARLVVAPTAPVASRRTVLRQGASGDAVRVLQRALRIKADGLFGPKTRAAVLSFQRARQLLPDGVVGPMTWAALGL
Physico‐chemical
properties
protein length:236 AA
molecular weight:24914,3 Da
isoelectric point:10,42
hydropathy:0,02
Representative Protein Details
Accession
7wBZw
Protein name
7wBZw
Sequence length
239 AA
Molecular weight
25402,79330 Da
Isoelectric point
10,17629
Sequence
MMNRIVWHHTGGGHVPNDTDRAAYHRLIDGDGRVHAGVHAIEANAPGARLVAGRYAAHTGGLNSGSIGLAVCAMAGGVWANPRASAAFPTPQQIDALISETVGLCRAYGIQPVRAHVLSHAEVPLTLGVVQKGKWDFDYQIRNAAGRDPLAIGDELRAEVMTRLGTASLWPVNEPKARRPVLRQGASGVHVRVLQRALRVADDGLFGPKTRAAVLSFQRARQLLPDGVVGPITWAALGL
Other Proteins in cluster: phalp2_22282
Total (incl. this protein): 14 Avg length: 257,1 Avg pI: 8,73
Protein ID Length (AA) pI
7wBZw 239 10,17629
3Vf0F 247 8,97240
43a5 281 5,98534
4QEWX 329 8,38677
4UcP2 234 7,84820
6QXcE 285 9,37623
7UIUB 239 9,63920
7cbWs 237 6,39981
7h6aK 239 8,71408
7pqOa 246 9,60406
7qyfL 291 9,67537
7vO2e 250 7,87973
7wF1e 246 9,13835
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_37317
7ZZsG
 35 43,6% 243 9.500E-79
2 phalp2_19974
6PE0f
 7 42,8% 250 9.886E-70
3 phalp2_21458
8eHRi
 401 42,5% 167 5.974E-62
4 phalp2_9404
8Fz4V
 29 42,3% 177 7.386E-58
5 phalp2_4723
4RvuF
 8 38,2% 188 9.003E-51
6 phalp2_1021
6Rshc
 90 44,5% 164 1.686E-50
7 phalp2_20043
1rrOC
 14 38,4% 169 1.632E-44
8 phalp2_25618
48uUY
 31 33,3% 228 5.730E-24
9 phalp2_16228
4NSsh
 1 29,0% 220 6.732E-19
10 phalp2_4585
4dFQ5
 9 28,1% 153 5.491E-16

Domains

Domains [InterPro]
Ami2
PG_1
Representative sequence (used for alignment): 7wBZw (239 AA)
Member sequence: A0AAX4QGK0 (236 AA)
1 239 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01471, PF01510

Taxonomy

  Name Taxonomy ID Lineage
Phage Nostoc phage Nsp-JY21
[NCBI] 		3128152 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
PP438413 [NCBI]
CDS location
range 38060 -> 38770
strand +
CDS
ATGATGAATCGCATCGTGTGGCATCACACGGGGGGCGGCCATCTGCCGAACGACACCGACAGGGCAGCATATCACCGGCTGATCGATGGGGATGGGCGGGTGCATGCAGGCATTCATTCGATCGAGGCGAACGCGCCGGGTGCGCGGCTGGTGACGGGGCGCTACGCCGCCCACACCGGGGGCCTCAATTCGGGATCGATCGGGCTGGCGGTTTGCGCGATGGCTGGCGGGGTCTGGGCCAACCCTCGGGCGTCTGCCGCTTTCCCGACGCCGGCACAGATCGATGCGGTGATTGCGGAAACGGTGGGCCTGTGCCGCACCTATGGCATCCAGCCGGTGCGCGCGCACGTCCTGAGTCATGCCGAAGTGCCGCTCACGCTGGGCGTGGTGCAAAAGGGCAAGTGGGATTTCGACTATCAGATCCGCAAGACCGCAGGCCGTGACCCGATTGCGATCGGCGATGAGTTGCGGGCGGAAGTTGCAGCGCGGCTTGTCGTGGCCCCGACTGCGCCGGTCGCGTCTCGCCGCACGGTGCTGCGGCAAGGCGCTTCGGGCGATGCGGTGCGGGTGCTGCAACGCGCCCTGCGCATTAAGGCGGATGGGCTGTTCGGCCCGAAAACCCGTGCCGCCGTGCTGTCATTCCAACGTGCGCGCCAGCTGCTGCCTGACGGGGTGGTTGGCCCCATGACCTGGGCCGCGCTTGGCCTTTAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (7wBZw) rather than this protein.
PDB ID
7wBZw
Method AlphaFoldv2
Resolution 89.73
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50