Protein

Protein accession
A0AAX4BIT2 [UniProt]
Representative
1gOR4
Source
UniProt (cluster: phalp2_38455)
Protein name
Peptidase M23 domain-containing protein
Lysin probability
100%
PhaLP type
endolysin
Probability: 97% (predicted by ML model)
Protein sequence
MTHKKKRRVTYALEYRDMFEDKDNSPDEVANSDWLDISKGINYGFVQGGAYEQETGVARYDGIDLNYVYDPVYSVIKGLVKVGWDPRGYGNYVMISDGAGLDVIYGHLSEVHVTTNQQVVPGTPLGISGNTGFSTGPHLHFEMRKNECCV
Physico‐chemical
properties
protein length:150 AA
molecular weight:16746,5 Da
isoelectric point:5,25
hydropathy:-0,46
Representative Protein Details
Accession
1gOR4
Protein name
1gOR4
Sequence length
1561 AA
Molecular weight
174461,05660 Da
Isoelectric point
8,87983
Sequence
MQKINNAVMDGGEGLQGFANVAGVSAEEFAELWQNDPYQALLIFQKGMKGVIDSGGNAKQTLEELGISELRETDTVLRLANGYGTMEDAQKYANEGWKEGTALSAEAEERYKTLGSQIQLFKNQLFATGRAIGEALAPYLTELMKKLTPLLKKLEEASDKTKVMIAAIAGIVIVMGPVFLTISLFAGALHQLSMGMGVVSTMAKGGLGLKKLGSLSKVASVSFKDLGGVFGWIVKSPLKLFTGSWGALKIALRTITGPVGIVITAVTVLSKIFITMYKKLDIFKDLVDGTIAVLGSFAKFIGGALGTAVKASVGFFKDMGSSAKEAGKEIGEKLSNSLKNAYDKLPDDGWVKKWGNYAKGLNEAIKSTKEPVDALGRNISKSTKKALGGFIELTEKATKQISEMRISVLSEEEQLTLDQVAEYKARGEKIPKEVQKQHDKILEKYGKHAEDLRGTYEEMKNESLTKMKEKHSTEEKEMQDFIEKTGAYTDEESEEIMKRLNKRHVDSQNSTEKNHNEILSIIDKGMEERGYLTEEELANIEKLQQESNETVVQTLSEGEKEQEVILQRLGTNKLAMNRETYEKLLNDSKEARDKTIQGAEEERDALIASAMESTTLTDEEKKKAVAAAEEQYEETVKNAEKTYNEVIGHASKQAEKHGVLVDQETGEVLSAWEGYWLKTKRFLAQTWNHIKGEFLRGWEQFKEWISGIWDYIVEKVKLAIASLSIVYSTIYDKFVEFFTGIWEYIVEKYHSFMESVGTFFTELYNKVVEFFVGIWEYLVEKYNSFMESLTNFFLGIYESITGFFTTVWTTIVEKYNSFMESLSGFFTSVVQAFVGFFTGLWETITSWLNNTVTWISGKYEELKLNISTFMTNVRNILVNGYTEVKTRVSSIVSSFVTAIVGFFTRLWQRATDITDKIKSFVIKVWDYIKLKVSSIVSSFKEAIVNRFTQMRTGISERVGKIKSNVHDGFVWIRSKVEGVVGKFKTKIVDIFEKMKSGIKSPIDKMKEFMTGLTDSVKTSLNKVIEGVNWVAKKIGMESQIPKLHTGTTHTTDYVTNGKINKDTLAVVGDRGRGNGPGGFRHEMIEDNKGNLTLTPSSDTIVPLKKGYKVHSGKATYDHFMKHFGEVPRFSRGTTNGGGGIFDKVKSVGNKAVNWAKNKISDVLDYVKNPGKLFNLVLDNLGFSNFKEVTGLHGDIARTGFKAVKENIVKKIKEWLESAEGDGGYINLSKGLNFGFASSAAAAKRAGYPFAMPHYGLDLNYVYDKLYSTVSGTATAKQDNSGFGKHMWIKAAKGLEVIYGHMSRFAFTGSKRVKPGTYLGVSGNTGRSTGPHLHYEMRKNGRPFDPLPWLKKNNRKKKGSDNGGGGDNDHPSHDIAPDLYNKLMQQVKDSPVQVSKREFKKYSESNKAQFEDPQDRMLAILNKTVDKFNPKNLNSYANGGLIRRHQIAEVGEGNKPEMVIPLTKKARAAHLIDLARRLVGLNEDGDVEIDNSTTVNNFNVDYTERLDKIEETLDSLATAMLQLVQGGMSVQINGREVAKQTYRDTDTFIKKEEKRRGKYRRD
Other Proteins in cluster: phalp2_38455
Total (incl. this protein): 3 Avg length: 1255,3 Avg pI: 7,86
Protein ID Length (AA) pI
1gOR4 1561 8,87983
CH2a 2055 9,44812
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_8198
7fTRt
 93 24,5% 1481 4.453E-101
2 phalp2_18614
7ATdb
 10 22,4% 1249 2.437E-67
3 phalp2_33783
1bUjO
 6 21,3% 1070 4.563E-42
4 phalp2_18582
7iQOB
 13 21,2% 1655 4.391E-28

Domains

Domains [InterPro]

No domain annotations available.

Taxonomy

  Name Taxonomy ID Lineage
Phage Staphylococcus phage S-CoN_Ph27
[NCBI] 		3076584 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
OR354850 [NCBI]
CDS location
range 35668 -> 36120
strand +
CDS
ATGACACACAAAAAAAAGCGACGTGTCACTTATGCTTTAGAATACAGAGATATGTTTGAAGATAAAGATAACAGCCCTGACGAAGTGGCTAACAGTGATTGGTTAGATATAAGCAAAGGTATCAATTACGGTTTCGTACAGGGTGGCGCATATGAACAAGAAACTGGCGTCGCAAGATATGACGGTATTGATTTAAATTACGTATACGATCCTGTTTATTCTGTTATCAAAGGTTTAGTCAAAGTCGGTTGGGATCCTAGAGGATATGGAAACTATGTAATGATAAGTGATGGTGCTGGCTTAGATGTTATATACGGACATTTAAGTGAAGTACACGTCACAACCAATCAACAAGTTGTACCCGGTACACCGTTAGGAATAAGTGGTAACACTGGTTTCAGTACAGGACCGCACTTACATTTTGAAATGAGAAAAAACGAGTGTTGCGTTTGA

Gene Ontology

Description Category Evidence (source)
GO:0004222 metalloendopeptidase activity molecular function None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (1gOR4) rather than this protein.
PDB ID
1gOR4
Method AlphaFoldv2
Resolution 57.11
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50