Protein

Protein accession
A0AAU8KZ58 [UniProt]
Representative
6ndmR
Source
UniProt (cluster: phalp2_30607)
Protein name
MurNAc-LAA domain-containing protein
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MIIGSRTGHSKNCLGAVSLRNEWACMSVLEQEVNKILKAHGHTIIDCNSSASTENGELSEGCRKANAQHIDIFLSYHMNASKDHKGHGTECWVHPNARASCKEIASRISSNLSKLGFYNRGVKTGLLYEMKNVNAPNIIIETCFCDNEKDIGIWSPTPYEVMARHIANAIDPTIPIEEKPKRWQIRVYAFTSKEEAEKCSDRITKELKAYNVVEELK
Physico‐chemical
properties
protein length:217 AA
molecular weight:24379,5 Da
isoelectric point:7,59
hydropathy:-0,47
Representative Protein Details
Accession
6ndmR
Protein name
6ndmR
Sequence length
343 AA
Molecular weight
37291,86580 Da
Isoelectric point
5,61861
Sequence
MKIAIDKGHCLYGFDTSADGRSVGGFSESEYDRILGDKIINLLRANGHEVIDVTVDNGNQFSSMYGSLGARTSKANANDVDLYIAIHFNAGGGRGTEVYLAPRSYYGSDSSYNTNLGYASRVQQKMVSLGFMNRGVKTEEFYVLVNTNAHAILIETCFCDSVADKQLYDSLGADKVAKAIVEGILNISVSTSTPSISTTTPTTSNAATNSDAPFRVRKSDNSPSSQIFASGTLEGAKANCPAGYCVFDKNGTLRYSNIPQASNSKTYAEDGTFYFTTNVQIRTQPCDGYETGLCYYAGESVIYHTVILDKNGFNWIVYNRSNGQQGYMKVRDLSTGEKYGYAE
Other Proteins in cluster: phalp2_30607
Total (incl. this protein): 8 Avg length: 269,4 Avg pI: 8,15
Protein ID Length (AA) pI
6ndmR 343 5,61861
1034D 317 8,88872
10D2I 317 9,00773
1pyu0 225 8,83580
3Y9NF 303 9,61644
E5G068 216 8,07861
A0AAU8L113 217 7,59337
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_32076
5RDQF
 9 40,1% 254 9.519E-52
2 phalp2_2703
7cyBj
 192 45,5% 215 2.114E-50
3 phalp2_35186
67E6C
 93 32,0% 278 6.782E-33
4 phalp2_12323
7wjSB
 3 30,9% 220 7.721E-27
5 phalp2_24413
4m1OU
 1246 29,6% 243 3.430E-19
6 phalp2_32087
63Erl
 43 30,4% 220 3.430E-19
7 phalp2_11988
35NoL
 2 26,2% 255 8.309E-19
8 phalp2_23918
1NTlO
 42 27,9% 265 1.264E-15
9 phalp2_21446
82r2O
 3 25,7% 260 1.264E-15
10 phalp2_38795
1mhnb
 2 24,0% 295 1.281E-09

Domains

Domains [InterPro]
Ami3
Unannotated
SH3_5
Representative sequence (used for alignment): 6ndmR (343 AA)
Member sequence: A0AAU8KZ58 (217 AA)
1 343 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01520, PF08460

Taxonomy

  Name Taxonomy ID Lineage
Phage Clostridium phage vB_CPP_X44
[NCBI] 		3232179 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
PP869283 [NCBI]
CDS location
range 9965 -> 10618
strand -
CDS
ATGATAATTGGAAGTAGAACAGGACACAGTAAAAACTGTTTAGGTGCGGTAAGCTTACGTAATGAGTGGGCGTGTATGAGTGTATTGGAGCAAGAGGTAAATAAAATACTTAAAGCTCACGGTCATACCATAATAGATTGTAATAGCTCCGCAAGTACAGAAAACGGGGAACTTTCGGAAGGGTGCAGGAAAGCAAACGCCCAACACATAGATATATTTTTATCCTATCACATGAACGCAAGTAAAGACCATAAGGGACACGGAACAGAGTGTTGGGTACACCCTAACGCAAGAGCATCATGTAAAGAAATAGCTTCAAGAATTTCAAGTAACCTTTCAAAATTAGGTTTTTATAATAGAGGGGTAAAAACTGGTTTATTATATGAAATGAAAAATGTAAATGCACCTAATATAATAATAGAGACTTGTTTTTGTGATAATGAGAAAGATATTGGAATATGGTCGCCTACACCATATGAGGTTATGGCAAGACATATCGCAAACGCCATAGACCCGACAATACCAATAGAAGAAAAACCGAAAAGGTGGCAAATCAGAGTTTACGCATTTACTAGCAAAGAAGAAGCAGAAAAATGTTCTGATAGAATAACAAAAGAATTAAAAGCGTATAACGTAGTAGAGGAGCTAAAGTAA

Gene Ontology

Description Category Evidence (source)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (6ndmR) rather than this protein.
PDB ID
6ndmR
Method AlphaFoldv2
Resolution 88.39
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50