Protein

Protein accession
A0AAU8HXQ8 [UniProt]
Representative
3lM8u
Source
UniProt (cluster: phalp2_40345)
Protein name
NlpC/P60 domain-containing protein
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MSVNEFARRLYWMCAEADGGYSQPNRLDVQRTRGVPGGPFTFEADCSSLVIEAARQAGYPTGRATYTGDMREQFAAAGWSVIPYAATAGLAANLYTGDVVLSEAASGGVGHVAAYIGDNRLAEAWIDGHGDIMGSAEGDGPGDDTGGETRVVAFSTHPYTLAGSWTHVLRPPAFTPPAGADAT
Physico‐chemical
properties
protein length:183 AA
molecular weight:19076,8 Da
isoelectric point:4,63
hydropathy:-0,19
Representative Protein Details
Accession
3lM8u
Protein name
3lM8u
Sequence length
277 AA
Molecular weight
29797,43790 Da
Isoelectric point
4,49837
Sequence
MALADLSAATMRWLCAAAYIGYSQLFRNDIYDGGSMDCSSGAAYSYNAGGVTPPFPADTSTHNFRERSIARGFAVLDYAAVGPYPDNLAVGDALLSELASGGVGHIAVVTGYNEVSEAWIAETGDIHGEPGDQTGGETRVVSFTDHPYTLNGSWTHVLRPPVDGDDTAPTQTTPTTTNTTKENHNMFLISTPLSDGSWSYALITETSGACTLDDQQKAAYIRMLGDARGYPWDWYWLLIREAWERHNALAATVGRETDEAADSIVARLQSGLTPKEA
Other Proteins in cluster: phalp2_40345
Total (incl. this protein): 52 Avg length: 285,3 Avg pI: 4,68
Protein ID Length (AA) pI
3lM8u 277 4,49837
1lHaT 295 4,54640
2bjCY 287 4,79632
2dilR 275 5,06512
3c5yp 284 4,79712
3c6c8 282 4,51997
3lM2a 289 4,53685
3lM8H 278 4,51884
3lMh0 282 4,34184
5Le43 295 4,55891
5LwSJ 285 4,83486
5N3PQ 295 4,65940
5P3Zr 297 4,43847
5RN9z 284 4,74631
5RQbS 289 4,86584
5SBeR 297 4,58329
5YQ2O 295 4,50718
6651x 292 4,46075
66J5J 295 4,64860
69Y0X 295 4,61563
6Yhww 270 5,03823
6ZtqP 271 4,43938
6aFXr 285 4,58130
6ch8T 289 4,64604
6clXh 291 4,89505
6fBZi 284 4,86061
6iEEt 288 4,77575
6iKrw 295 4,57136
6iUyl 295 4,65036
6jIpr 296 4,57300
6jgfT 289 4,86504
6p3Gn 282 4,54242
6suPe 268 4,54993
6tp0f 275 4,94808
6vQ3M 296 4,64860
73fIG 288 4,59921
73fIg 290 4,78814
74zGy 297 4,50809
7NP5o 295 4,56584
7Ow1G 287 4,87147
8oA9C 288 4,84492
Cqee 296 4,57005
EIU9 286 4,53577
HrcJ 278 4,62552
Hz4e 288 4,82389
NDtf 289 4,76478
NkZP 289 4,89341
OKNw 295 4,61563
jHb5 296 4,60483
pabA 262 5,25757
wPqV 287 4,88209
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_29768
1HIrS
 22 34,4% 203 2.078E-33
2 phalp2_6205
62kfV
 15 21,8% 279 1.361E-24
3 phalp2_18094
3ZYin
 3 29,1% 185 3.340E-13
4 phalp2_5480
3cwb6
 3 26,4% 178 1.546E-11

Domains

Domains [InterPro]
Unannotated
Unannotated
Representative sequence (used for alignment): 3lM8u (277 AA)
Member sequence: A0AAU8HXQ8 (183 AA)
1 277 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Decurrovirus sp
[NCBI] 		2832697 Decurrovirus >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
PP870127 [NCBI]
CDS location
range 15565 -> >16114
strand +
CDS
ATGAGTGTTAACGAGTTTGCGCGGCGCCTGTATTGGATGTGCGCAGAAGCCGACGGCGGGTACTCGCAGCCGAACCGCCTCGACGTGCAACGTACCCGCGGTGTACCCGGCGGCCCCTTCACCTTCGAGGCAGATTGCTCAAGCCTCGTTATCGAAGCTGCCCGGCAAGCCGGATACCCGACCGGACGCGCCACCTATACCGGCGACATGCGCGAGCAGTTCGCCGCCGCCGGTTGGTCCGTCATCCCATACGCCGCTACCGCTGGCCTCGCTGCGAACCTCTACACCGGCGATGTTGTACTTTCCGAAGCCGCGTCCGGCGGCGTGGGACACGTCGCCGCCTATATCGGCGACAACCGTCTAGCCGAAGCATGGATAGACGGACACGGCGACATTATGGGCAGCGCCGAAGGCGACGGCCCCGGCGACGACACCGGCGGTGAGACCCGCGTCGTCGCATTCTCAACCCACCCCTACACACTCGCAGGCAGTTGGACGCACGTCCTACGCCCGCCCGCGTTCACCCCGCCCGCCGGGGCCGACGCCACCC

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008234 cysteine-type peptidase activity molecular function None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (3lM8u) rather than this protein.
PDB ID
3lM8u
Method AlphaFoldv2
Resolution 87.17
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50