Protein

Protein accession
A0AAU8B8Q2 [UniProt]
Representative
3B8xP
Source
UniProt (cluster: phalp2_1849)
Protein name
PGrP protein
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MNLLKCILTANDCYKANQRITPKGVMVHSTGANNPTLKRYVQPLKGDADYDALMAQLGTNTNANSWNRSGTNACVHAFIGKLADGSIAAVQTLPWNWRGWHAGSGTTRSSANNSHISFEICEDDLKDANYFAQVYQTAVELTAMLCKEYNLDPLADEVVICHAEGYRLGMASGHADVEHWFPRHGKTMDDFRADVARTIQEDDDMTQENFKTMWQELRKELQSEAASSWSGEALQWAESNGIMLGDDKGNLLPLDLLTREQMAVMLYRFAQWLGKA
Physico‐chemical
properties
protein length:276 AA
molecular weight:30829,3 Da
isoelectric point:5,25
hydropathy:-0,44
Representative Protein Details
Accession
3B8xP
Protein name
3B8xP
Sequence length
159 AA
Molecular weight
18614,47110 Da
Isoelectric point
4,77041
Sequence
HIAFEICEDGLADADYFRRVYREAVELTAYLCRLYGLDPLEPGVVIDHKEGHDLGIASGHGDVEHWFPRHGKTMDDFRRDVEKELKGGEDDMTQEQFDAMMEDYLRRLSEQEPEGWSAEAREWAEDNGIIRGDEHGNKQYRSFCTREQMVVFLKRVKEM
Other Proteins in cluster: phalp2_1849
Total (incl. this protein): 7 Avg length: 189,1 Avg pI: 5,75
Protein ID Length (AA) pI
3B8xP 159 4,77041
139iw 149 4,94274
1FSES 221 6,74732
5RNJX 169 5,59855
62qnl 169 5,28434
6UHEw 181 7,64055
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_16169
4y8Oi
 1 33,8% 136 1.375E-30
2 phalp2_20567
4ya0O
 12 35,2% 173 5.421E-28
3 phalp2_8689
83MnM
 2 23,4% 166 8.441E-10
4 phalp2_8663
7V0AW
 3 24,6% 166 3.949E-09

Domains

Domains [InterPro]
Unannotated
Unannotated
Representative sequence (used for alignment): 3B8xP (159 AA)
Member sequence: A0AAU8B8Q2 (276 AA)
1 159 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Dulem virus 33
[NCBI] 		3145751 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
PP511792 [NCBI]
CDS location
range 18117 -> 18947
strand +
CDS
ATGAATCTGTTGAAATGTATTCTCACCGCCAACGACTGCTACAAGGCCAACCAACGGATCACGCCAAAGGGTGTGATGGTGCACTCCACCGGGGCAAATAACCCCACGCTGAAGCGGTATGTCCAGCCCCTAAAAGGCGACGCGGACTATGACGCGCTGATGGCGCAGCTGGGGACCAACACCAACGCCAACAGCTGGAACCGGAGCGGCACCAATGCCTGTGTCCACGCCTTTATCGGGAAGCTGGCGGACGGCAGCATTGCGGCGGTACAGACCCTGCCCTGGAATTGGCGGGGGTGGCACGCGGGGAGCGGAACTACCCGGAGCAGCGCCAACAACTCTCACATAAGCTTTGAAATCTGTGAGGACGATCTGAAGGACGCAAACTACTTTGCGCAGGTCTACCAGACAGCGGTGGAGCTGACGGCCATGCTGTGCAAAGAGTATAACCTTGATCCGCTGGCCGATGAGGTAGTGATCTGTCACGCGGAGGGGTACCGGCTGGGGATGGCCTCTGGTCACGCAGATGTGGAGCACTGGTTCCCCCGGCACGGGAAGACAATGGACGATTTTAGGGCAGATGTGGCCCGGACAATACAGGAGGATGATGATATGACACAAGAAAACTTTAAAACGATGTGGCAGGAACTGCGCAAGGAACTCCAAAGCGAAGCTGCGTCCAGCTGGAGTGGAGAAGCTCTACAGTGGGCGGAGTCCAACGGCATCATGCTCGGTGACGACAAGGGCAATCTGCTGCCCCTGGATCTGCTAACACGAGAGCAGATGGCGGTGATGCTGTACCGCTTTGCTCAGTGGCTGGGCAAGGCGTGA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (3B8xP) rather than this protein.
PDB ID
3B8xP
Method AlphaFoldv2
Resolution 92.91
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50