Protein

Protein accession
A0AAU8AU77 [UniProt]
Representative
3fLr8
Source
UniProt (cluster: phalp2_20427)
Protein name
PGrP protein
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MKRIIIHWTAGTNKPCGEDFKHYHYLITGLGEVRSGEFKPEDNENCNDGKYAAHTGGGNTGSIGVSMCGMAGFNKRKESTKYPLTKIQCERMFKLCAELCKKYNIPITPDTVMTHYEFGKKHPKTTSYGKIDITFLHPWENLTAAQIGDFIRNKVKWYYNNL
Physico‐chemical
properties
protein length:162 AA
molecular weight:18492,0 Da
isoelectric point:9,06
hydropathy:-0,65
Representative Protein Details
Accession
3fLr8
Protein name
3fLr8
Sequence length
113 AA
Molecular weight
12559,39640 Da
Isoelectric point
9,34007
Sequence
LYAAHCGGGNTGRIGVALCGMAGFKSRQFVGAYPLTKKQCEAGFKLLAELAKEYKYIITPQTVQTHYEFGKANPKTSSAGKIDIIYLPPYPDIKQDDVGEFIRSKVKWYYSKI
Other Proteins in cluster: phalp2_20427
Total (incl. this protein): 7 Avg length: 148,3 Avg pI: 9,10
Protein ID Length (AA) pI
3fLr8 113 9,34007
1dbq0 164 8,40025
2S4Ao 149 8,88189
40mZo 179 9,12919
fBRS 92 9,49060
A0A8S5TKE9 179 9,39725
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_15223
QCVp
 291 64,5% 110 3.745E-49
2 phalp2_21458
8eHRi
 401 38,8% 121 1.633E-22
3 phalp2_27664
6EnWw
 2 37,0% 81 1.125E-11

Domains

Domains [InterPro]
Unannotated
Representative sequence (used for alignment): 3fLr8 (113 AA)
Member sequence: A0AAU8AU77 (162 AA)
1 113 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Dulem virus 31
[NCBI] 		3145749 Petitvirales > Microviridae > Microvirus >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
PP511318 [NCBI]
CDS location
range 19304 -> 19792
strand +
CDS
ATGAAACGTATAATAATACACTGGACAGCTGGCACAAACAAGCCTTGCGGTGAAGATTTTAAACATTACCACTATTTAATTACCGGCTTGGGAGAGGTTCGCTCCGGAGAATTCAAGCCGGAAGATAATGAGAATTGTAATGATGGTAAATACGCAGCCCATACAGGTGGCGGTAATACCGGTAGTATCGGAGTTTCTATGTGTGGTATGGCAGGTTTTAACAAGCGGAAAGAATCTACCAAATACCCATTAACAAAAATCCAGTGTGAAAGAATGTTTAAGCTTTGTGCCGAACTCTGCAAAAAGTACAATATACCTATAACGCCTGATACTGTTATGACTCATTACGAGTTCGGTAAGAAACACCCTAAGACAACAAGCTATGGCAAAATAGACATAACTTTTTTACATCCTTGGGAAAATCTTACCGCCGCGCAAATCGGCGACTTTATCCGAAATAAAGTTAAATGGTATTACAATAATCTATAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (3fLr8) rather than this protein.
PDB ID
3fLr8
Method AlphaFoldv2
Resolution 92.47
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50