Protein

Protein accession
A0AAU7GXA4 [UniProt]
Representative
7tMqT
Source
UniProt (cluster: phalp2_20967)
Protein name
Endolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MRSGINWRGTVNHRKGDMATKMMTAAQFLAALKAEGVPVRERSGWRTHNRNHKGKWGPPNGVMVHHTASGTSGIEEYVATGTSALPGPLCHGLIEKSGTVVLVGWGRANHAGGGDPDVLRAVRAEQWPVPKTNEHAGSTGSVDGNPHFVGYECVNRGDGKDSWPALQLEAIARASAAVCRHYGWSVDSVIRHLDWSDWKSDPRGVDWTKMRARIATILKGKPNATPFTSWADGDGDTEQPEQPGKPEQPQPSDPDAFPGAAKFGPGKSGSHITRLGQMLVKRGGGRFYSVGPGPRWGEADRKATEAFQRAQGWTGSDADGIPGPTTWRLLVTGKGKSIPAAPAKKPVVSLANVIAASRRDPAAAQGKTSHPKDVKLVEAALLKLGFLGKTYAADGAYGTTTVAAYNAFRRSIGLKGADAAGDPGRQSLGTLGSRSGLFTVK
Physico‐chemical
properties
protein length:441 AA
molecular weight:46691,0 Da
isoelectric point:9,88
hydropathy:-0,52
Representative Protein Details
Accession
7tMqT
Protein name
7tMqT
Sequence length
488 AA
Molecular weight
51959,21730 Da
Isoelectric point
9,66724
Sequence
LHSLAEFLVRGQLRIVRIYGPHFPLDSFIHERPAGRLVYLEVHLSQVSDTISIAASQVGYQAERAPGERPSGHQKYSGQVPGLEWSNFQPWCAVWVAWVALKAGVASLYPRTASCSNGVQWFRDRGRFSNYPAIGAQVFYGPGGGTHTGIVYAYDANSIYTYEGNTSLSNDANGNKVMRRERRRRDAYVYGYGLPQFTEGVTTSDPALTGQAGFTYAASASGPAGNSGSTKPTSPPRTVTVRAGQTITAIAAAAGISVAALLSLNPGVKDHPDQIHPGDSITLPAVPDGGLEPQPTPEPPTTTPPPVSPPASNSGNAFPGAGQFGPGANNSSVTRLGELLVQRGAGRFYSEGPGPRWGEADRQAVKAFQMAQGWTGSSADGIPGPQTWALLVTHQGRDIPAATSTKPSAAPAFPGANRFRPGAVNQHVTKLGEQLVRKGYSRYYRQGPGPRWTEADRRAVQAFQHAQGWSGSAADGYPGPLTWSRLMR
Other Proteins in cluster: phalp2_20967
Total (incl. this protein): 4 Avg length: 427,3 Avg pI: 9,68
Protein ID Length (AA) pI
7tMqT 488 9,66724
A0A2D1GP54 425 9,80076
A0A1V0E659 355 9,36089
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_13865
7ucym
 2 38,7% 341 1.068E-48
2 phalp2_20894
6Udpv
 9 32,3% 328 6.201E-20
3 phalp2_18419
68khh
 16 25,5% 356 1.495E-05

Domains

Domains [InterPro]
Disordered region
Unannotated
LysM
Unannotated
Unannotated
Representative sequence (used for alignment): 7tMqT (488 AA)
Member sequence: A0AAU7GXA4 (441 AA)
1 488 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01476

Taxonomy

  Name Taxonomy ID Lineage
Phage Streptomyces phage Geonosis
[NCBI] 		3158856 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
PP750866 [NCBI]
CDS location
range 25802 -> 27127
strand +
CDS
ATGCGCTCGGGCATAAACTGGCGGGGCACCGTCAACCACCGGAAGGGTGACATGGCCACCAAGATGATGACCGCCGCGCAGTTCCTCGCGGCGCTGAAAGCCGAGGGCGTCCCGGTCCGCGAGCGGTCCGGCTGGCGCACGCACAACCGGAACCACAAGGGGAAGTGGGGGCCGCCCAACGGCGTCATGGTCCACCACACCGCCTCGGGCACGAGCGGGATCGAAGAGTACGTGGCGACCGGCACCAGCGCGCTGCCGGGACCGCTGTGCCACGGGCTGATCGAGAAGTCCGGAACGGTGGTGCTGGTCGGGTGGGGCCGCGCGAACCACGCGGGTGGCGGGGACCCTGACGTCCTGCGCGCGGTCCGGGCCGAGCAGTGGCCGGTGCCGAAGACGAATGAGCATGCCGGGTCCACCGGCTCGGTGGACGGCAACCCGCACTTCGTCGGGTACGAGTGCGTGAACCGTGGCGACGGGAAGGACAGCTGGCCGGCGCTTCAGCTCGAAGCCATCGCGCGCGCCTCGGCCGCTGTCTGCCGTCACTACGGCTGGTCCGTGGACAGCGTGATCCGTCACCTCGACTGGTCCGACTGGAAGTCGGACCCGCGCGGCGTGGACTGGACGAAGATGCGCGCCCGCATCGCCACCATCCTGAAGGGGAAGCCGAACGCCACGCCGTTCACGTCGTGGGCGGACGGTGACGGGGACACCGAGCAGCCCGAGCAGCCGGGGAAGCCCGAGCAGCCGCAGCCCTCGGACCCTGACGCCTTCCCCGGCGCGGCGAAGTTCGGCCCCGGCAAGAGCGGCAGCCACATCACGCGCCTCGGGCAGATGCTCGTGAAGCGTGGCGGTGGCCGCTTCTACAGCGTCGGTCCCGGCCCCCGGTGGGGTGAGGCTGACCGGAAGGCCACCGAGGCGTTCCAGCGGGCGCAGGGCTGGACCGGCAGTGACGCGGACGGCATCCCCGGCCCGACCACGTGGCGGCTGCTGGTGACCGGCAAGGGGAAGTCCATCCCTGCGGCGCCCGCGAAGAAGCCGGTGGTGTCCCTGGCCAACGTCATCGCGGCGTCCCGCCGGGACCCCGCTGCCGCGCAGGGGAAGACGTCGCACCCGAAGGACGTCAAGCTGGTGGAAGCGGCGCTGCTGAAGCTGGGGTTCCTCGGGAAGACGTACGCCGCTGACGGTGCGTACGGCACCACAACTGTGGCCGCGTACAACGCGTTCCGCCGCAGCATCGGGCTGAAGGGCGCGGACGCCGCTGGCGATCCGGGCCGGCAGTCCCTCGGGACACTGGGCAGCCGCTCGGGTCTCTTCACCGTGAAGTAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (7tMqT) rather than this protein.
PDB ID
7tMqT
Method AlphaFoldv2
Resolution 77.52
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50