Protein

Protein accession
A0AAU7GWJ5 [UniProt]
Representative
5nNrs
Source
UniProt (cluster: phalp2_35982)
Protein name
Endolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MSLTQKVIDIASGEIGYHEGKDSSGHWNNKEKYAAQVPGLEWADYQAWCATFVSWVALKAGAASLYPRTASCLAGVAWFKKAGRFSEYPAVGAQVFYGSGGGTHTGIVISYDADTITTVEGNTNDNGSAEGDGVYRKVRQRRSDFVYGYGYPDFPEGIKSADPKWASKAPTTPAKPAPAKPAPAKPAPKPNPIYKLSDAVKPGATHVQVADIQQLLIKLGYKIPGAVTNFYGKNTEAAVALWHERNPKYKNVGLRRDTRIGPAGYVALQKQCGRR
Physico‐chemical
properties
protein length:275 AA
molecular weight:29698,2 Da
isoelectric point:9,46
hydropathy:-0,47
Representative Protein Details
Accession
5nNrs
Protein name
5nNrs
Sequence length
412 AA
Molecular weight
43670,39750 Da
Isoelectric point
8,59004
Sequence
MAVLGVDVSSYQPVAFDTKGLAFAFVKVTEGTSYVNPRYSGQVATARKAGLVLGHYHFGKAGNGAAQADYFLSKVSLKPGDILAFDWEDSAVTQADRDAFLSRVKAKAPGHKVVLYCNTDYWLKRDSNNGGPMDGLWIADPNHAAGHPGIQHAWTFHQYSFAGGIDKNVANFADAAHLRAWATPAAPKPAPAPAPAPSAGHAADVLRVAKAEIGYHEGKDASGNWDNIQKYSTGVPGLEWSQGQPWCCTFCAWVALKAGVANLFPRTASCADAVAWFKQQGRWSDYPAIGAQVFYGPGGGSHTGIVVDYDADTITTVEGNTNNNGSAEGDGVYLKKRNRRDVNTFGYGYPKYPEGIKSADPAYASQAPKPAPAPAPVKPTPAPVPAPAPAPTLEQRVSALETAVKALQSKVK
Other Proteins in cluster: phalp2_35982
Total (incl. this protein): 19 Avg length: 451,2 Avg pI: 7,05
Protein ID Length (AA) pI
5nNrs 412 8,59004
5B2gm 474 5,04886
5nMM1 490 5,22239
5nNHV 417 8,12426
5nOCW 415 8,12426
5nP86 417 8,12883
6AIS8 484 5,91259
6CChV 503 8,93140
6DhWY 479 5,46816
6Dhum 474 5,42536
6Doz3 483 5,70194
6E0TI 479 5,58582
6EQra 422 9,25781
6KOsf 535 9,32653
6TU3u 485 5,67369
7o6L3 575 4,59108
7zkk2 478 6,05252
A0A411B102 275 9,31183
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_1090
7qVe4
 1 25,9% 370 2.058E-25
2 phalp2_30848
jqQ5
 8 25,8% 337 5.881E-19
3 phalp2_30569
5JNBP
 2 24,9% 341 3.130E-14

Domains

Domains [InterPro]
GH25
CHAP
Representative sequence (used for alignment): 5nNrs (412 AA)
Member sequence: A0AAU7GWJ5 (275 AA)
1 412 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01183, PF05257

Taxonomy

  Name Taxonomy ID Lineage
Phage Streptomyces phage Kamino
[NCBI] 		3158857 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
PP750867 [NCBI]
CDS location
range 22297 -> 23124
strand +
CDS
GTGAGTCTCACTCAGAAGGTCATCGACATCGCCTCCGGCGAGATCGGCTACCACGAAGGCAAGGACTCCAGCGGCCACTGGAACAACAAGGAGAAGTACGCGGCTCAGGTTCCCGGCCTGGAGTGGGCGGACTACCAGGCGTGGTGCGCCACGTTCGTGAGCTGGGTCGCGCTGAAGGCTGGAGCCGCGTCGCTCTACCCGCGCACCGCGAGCTGCCTGGCTGGCGTCGCCTGGTTCAAGAAGGCTGGTCGCTTCAGCGAGTACCCGGCTGTCGGCGCGCAGGTCTTCTACGGCTCGGGCGGTGGCACGCACACCGGCATCGTCATCAGCTACGACGCCGACACGATCACCACGGTCGAGGGCAACACCAACGACAACGGCTCCGCCGAGGGTGACGGCGTCTACCGCAAGGTGCGTCAGCGTCGCAGCGACTTCGTCTACGGCTACGGCTACCCGGACTTCCCCGAGGGCATCAAGTCGGCGGACCCGAAGTGGGCGAGCAAGGCTCCGACGACCCCGGCCAAGCCCGCCCCCGCGAAGCCTGCCCCGGCCAAGCCTGCGCCCAAGCCGAACCCGATCTACAAGCTGAGCGACGCGGTCAAGCCCGGTGCGACCCACGTCCAGGTGGCCGACATCCAGCAGCTTCTGATCAAGCTCGGCTACAAGATCCCCGGCGCGGTGACCAACTTCTACGGCAAGAACACCGAGGCCGCTGTCGCCCTGTGGCACGAGCGGAACCCGAAGTACAAGAACGTCGGCCTGCGTCGCGACACCCGCATCGGTCCGGCTGGGTACGTCGCCCTCCAGAAGCAGTGTGGTCGCCGATGA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (5nNrs) rather than this protein.
PDB ID
5nNrs
Method AlphaFoldv2
Resolution 90.00
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50