Protein

Protein accession
A0AAU6R5Y9 [UniProt]
Representative
2G2v9
Source
UniProt (cluster: phalp2_5407)
Protein name
Endolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MAKFSSLIDGTTSDHGKNRGSDPNKKRIIVHHWAGTAGGDTALMKPKGQNSRGDVSASYILYSSGKLIGQVSEEYSPWTTGSADWGSVTVETQNAANGGNWPIDQRAKDKLAQLMADLSDRYGWGELKLGTNVRYHGEFYATACPGPDMIASLPAIIAKANQLRKGGGGKPSGGGDTGTYTVSKGETLSGIAAKYGTTWQVLQSLNGLSDPNKIYPGQKIKVPGSSGGGTSKPSQSLSEVAKAVIRGDYGNGSTRVAKLRAAGYDPAEVQREVNRQLGIGGSTTTSTNASTIDRLAREVIRGDWGNDPERKRRLEAAGYDYSAVQRRVNQLI
Physico‐chemical
properties
protein length:332 AA
molecular weight:35224,8 Da
isoelectric point:9,55
hydropathy:-0,62
Representative Protein Details
Accession
2G2v9
Protein name
2G2v9
Sequence length
275 AA
Molecular weight
29341,11240 Da
Isoelectric point
10,09783
Sequence
KSLGYSKVDLYTGSSFYNTYLKPGQLAVDKPWLARYPLYPETGQPTPVWYNGQKGAWQWSSTYKFAGIPGYFDVSQDYAGKYTNVAKVDNATSTGVVKKIGSLSLVDYLKSKGKSATFSARAKLAAQYGITNYSGTAAQNLALLSKLKSGVKPAKVNTTSSKLTTSSSAAKSASTTVKTYTVKRGDTLSGIAAKYGTSVATLQKLNGISNPNKIYAGQKLKISGIATAKQYYTVRAGDTLSGIAAKYGTSVSRLASLNGIKNPNLIRVGQKLRVK
Other Proteins in cluster: phalp2_5407
Total (incl. this protein): 4 Avg length: 309,5 Avg pI: 9,68
Protein ID Length (AA) pI
2G2v9 275 10,09783
A0A386K875 314 9,55855
A0A5B9NH46 317 9,53038
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_21701
3ifCN
 920 37,9% 290 2.149E-36
2 phalp2_11359
7wNq4
 16 37,6% 242 1.435E-33
3 phalp2_33491
7wA0y
 13 38,7% 222 9.427E-31
4 phalp2_22096
5ZSom
 2292 31,8% 229 1.031E-16
5 phalp2_21686
3dOCR
 8 31,4% 229 3.012E-14
6 phalp2_25839
5j1l4
 12 30,2% 248 4.631E-12
7 phalp2_38217
7u45O
 5 27,4% 273 1.669E-08
8 phalp2_34315
3GJC6
 151 23,1% 290 5.318E-08

Domains

Domains [InterPro]
GH25
Unannotated
LysM
LysM
Representative sequence (used for alignment): 2G2v9 (275 AA)
Member sequence: A0AAU6R5Y9 (332 AA)
1 275 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01183, PF01476

Taxonomy

  Name Taxonomy ID Lineage
Phage Micrococcus phage Olihed
[NCBI] 		3092209 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
OR756648 [NCBI]
CDS location
range 17789 -> 18787
strand +
CDS
ATGGCGAAGTTCAGTAGCCTGATCGACGGCACCACGTCGGATCACGGCAAGAACCGGGGCTCGGACCCCAACAAGAAGCGGATCATCGTCCACCACTGGGCGGGGACCGCTGGCGGTGACACCGCGCTGATGAAGCCGAAGGGCCAGAACTCGCGCGGCGACGTGTCGGCGTCGTACATCCTGTACAGCTCGGGCAAGCTCATCGGCCAGGTGTCGGAGGAGTACAGCCCGTGGACGACCGGTTCGGCTGACTGGGGTTCGGTCACGGTCGAGACCCAGAACGCGGCGAACGGCGGCAACTGGCCCATCGACCAGCGCGCCAAGGACAAGCTCGCACAGCTGATGGCGGACCTGTCGGACCGGTACGGCTGGGGCGAGCTCAAGCTCGGTACCAACGTCCGGTACCACGGCGAGTTCTACGCCACGGCATGCCCTGGCCCGGACATGATCGCCTCCCTGCCCGCCATCATCGCGAAGGCGAACCAGCTCCGGAAGGGTGGCGGGGGTAAGCCCTCCGGCGGTGGCGACACCGGCACCTACACGGTCTCGAAGGGTGAGACCCTGTCGGGCATCGCGGCGAAGTACGGCACCACGTGGCAGGTCCTCCAGTCGCTCAACGGTCTGTCGGACCCGAACAAGATCTACCCGGGCCAGAAGATCAAGGTCCCGGGCTCGTCGGGCGGTGGCACGTCGAAGCCGTCCCAGTCTCTCTCGGAGGTCGCTAAGGCGGTCATCCGTGGCGACTACGGCAACGGCTCCACCCGCGTGGCGAAGCTCCGCGCGGCGGGCTACGACCCGGCGGAGGTCCAGCGCGAGGTCAACCGTCAGCTCGGGATCGGCGGGTCGACCACGACCAGCACGAACGCGTCCACCATCGACCGGCTGGCCCGCGAGGTCATCCGGGGCGACTGGGGGAACGACCCTGAGCGGAAGCGTCGCCTGGAGGCGGCGGGATACGACTACTCGGCTGTTCAGCGTCGGGTCAACCAGCTGATCTGA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0008932 lytic endotransglycosylase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (2G2v9) rather than this protein.
PDB ID
2G2v9
Method AlphaFoldv2
Resolution 78.73
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50