Protein

Protein accession
A0AAT9JCS8 [UniProt]
Representative
71AR5
Source
UniProt (cluster: phalp2_7758)
Protein name
Endolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MKLQYLVIHCTATPEGRGVSAADIKRWHTSPPSKGGRGWDRVGYTDMVHPNGRVERLVDNNEDGLVDPWERTNGAKGHNSVSRHIVYVGGLTTDGKAAKDTRTPEQRKALEKYVKDFHAKHPDVRIIGHNEIAAKACPCFDVQAWLRSIGINQPTKK
Physico‐chemical
properties
protein length:157 AA
molecular weight:17502,6 Da
isoelectric point:9,45
hydropathy:-0,75
Representative Protein Details
Accession
71AR5
Protein name
71AR5
Sequence length
244 AA
Molecular weight
26529,34870 Da
Isoelectric point
5,68313
Sequence
MGKLTFLIIHCTATPAGRKVTSDDIRNWHIKGRGWKQVGYSDMIHEDGTVENLVPYNEDDVIEAWELTNGAVGMNGISRHIVYVGGLDANGEKPEDTRTDAQLEAMEHYIHQMIEKHPAILIGGHNQFAAKACPSFDTAKWLDEISIDPANIYLTAAQKKAKAEAEAKAKAKAEAKAKAKAEADAKAKQPKDKATQDAKAKDKVKDGKTQDKKPEDSGSEKPEDSGDGKTETPAPPADDTPKTE
Other Proteins in cluster: phalp2_7758
Total (incl. this protein): 15 Avg length: 148,5 Avg pI: 8,92
Protein ID Length (AA) pI
71AR5 244 5,68313
A0A455ZIK7 154 9,32279
A0A8S5MNP7 47 9,42813
A0A8S5MRD1 154 9,37978
A0A8S5MSC5 154 9,51233
A0A8S5NBM3 157 9,07562
A0A8S5NBS4 154 9,29881
A0A8S5TFS4 154 8,55136
A0AAT9J811 68 6,81610
A0AAT9J8C4 157 9,42633
A0AAT9JB38 157 9,42633
A0AAT9JB58 157 9,42633
A0AAT9JBJ1 157 9,51439
A0AAT9JBS4 157 9,42633
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_14613
5sQyS
 2 56,8% 153 9.986E-65
2 phalp2_21699
3i7KR
 33 41,5% 190 2.397E-43
3 phalp2_18379
5Eq5Q
 10 44,0% 150 3.168E-40
4 phalp2_23354
5DkBI
 3 27,5% 156 2.280E-11
5 phalp2_17467
4UUVw
 16 26,6% 180 2.462E-10
6 phalp2_31037
1Au9U
 14 27,2% 169 4.455E-10
7 phalp2_6791
7Z5KX
 1 22,4% 156 1.202E-07
8 phalp2_29629
82XcD
 5 24,4% 168 2.158E-07

Domains

Domains [InterPro]
Ami2
Disordered region
Representative sequence (used for alignment): 71AR5 (244 AA)
Member sequence: A0AAT9JCS8 (157 AA)
1 244 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01510

Taxonomy

  Name Taxonomy ID Lineage
Phage Porphyromonas phage phage012a_381OKJP
[NCBI] 		3154102 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK068093 [NCBI]
CDS location
range 19262 -> 19735
strand +
CDS
ATGAAGCTGCAATACTTAGTCATTCATTGCACTGCCACGCCCGAGGGGCGTGGCGTAAGTGCGGCGGACATCAAACGCTGGCATACCTCCCCCCCCTCAAAGGGCGGGAGGGGCTGGGACCGAGTCGGTTATACCGATATGGTGCATCCTAATGGCCGTGTCGAGCGTCTCGTGGACAATAACGAGGACGGTTTGGTAGACCCGTGGGAACGTACCAACGGAGCCAAGGGCCACAATTCTGTTTCCCGGCATATCGTCTATGTGGGCGGATTGACCACGGATGGCAAAGCAGCAAAAGATACCCGCACCCCGGAGCAACGAAAAGCACTGGAGAAGTACGTCAAAGACTTTCATGCAAAGCACCCGGACGTGCGTATAATCGGGCATAACGAAATCGCCGCCAAGGCCTGCCCCTGCTTCGACGTGCAGGCCTGGCTGCGCTCGATCGGAATCAATCAACCAACAAAAAAGTAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (71AR5) rather than this protein.
PDB ID
71AR5
Method AlphaFoldv2
Resolution 84.81
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50