Protein

Protein accession
A0AAF0RV25 [UniProt]
Representative
4LEw1
Source
UniProt (cluster: phalp2_34505)
Protein name
Lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 91% (predicted by ML model)
Protein sequence
MGAYDKFIQDILPYAKEIENKYHIPTSVTIGQAVLESAGGTRTPKDVYSGKESYNLFGVKGSGDNGSVKSWTTEVYGGVSQRIVANFRSYSSWYGSLEDYAKLLTGASRYAGAFKTNNPYDFVSEVRKAGYATDPSYTSKVTSIMDKYNLTQYDGDKYKGKPVSGGTGGATKPVYESDDKTTKEEHDRLSQESEERGHRIFYIPIPGTDGIEIYSGQMFSFMLMAVGVILAILALYSMFLKDSVIIQTEGEPA
Physico‐chemical
properties
protein length:253 AA
molecular weight:27862,8 Da
isoelectric point:5,51
hydropathy:-0,44
Representative Protein Details
Accession
4LEw1
Protein name
4LEw1
Sequence length
235 AA
Molecular weight
26714,44490 Da
Isoelectric point
4,63359
Sequence
MGKKQDDFIALVVPGAQQVQKEIGMFASVTIAQAAWETGWGTSTPKDIQTGEESYNLFGRKAAGDDPYVESWTWEVYNGNRETILARFKKFDSYEASILDRSQFLTLPWYQRACKADNPWDAARFLIDTGYPGYSYATDPTYIANIHSIMKSYDLTQYDILPQEESDIMELTNEQWNHLYKVFDGLYDQMVNKGNPAGLSSWDWAKKVAERNLTVSEAVYLSLVLHGRDEGVEGV
Other Proteins in cluster: phalp2_34505
Total (incl. this protein): 3 Avg length: 251,3 Avg pI: 5,11
Protein ID Length (AA) pI
4LEw1 235 4,63359
5hQGY 266 5,19204
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_28108
7xE0g
 17 43,3% 157 3.504E-33
2 phalp2_3928
71QA3
 192 37,5% 168 1.076E-31
3 phalp2_2026
2muJS
 52 39,1% 179 1.003E-28
4 phalp2_29619
83Xjg
 46 38,2% 157 4.733E-28
5 phalp2_5346
2cQBB
 648 41,0% 156 1.200E-27
6 phalp2_9991
3fZEe
 50 37,7% 172 6.735E-26
7 phalp2_5784
7N5g9
 18 38,7% 155 1.251E-25
8 phalp2_374
7enmQ
 47 33,3% 168 5.872E-25
9 phalp2_37638
4fbgK
 5 36,6% 161 3.750E-24
10 phalp2_23271
4Y2T6
 95 38,7% 160 3.253E-23

Domains

Domains [InterPro]
GLUCO
Unannotated
Representative sequence (used for alignment): 4LEw1 (235 AA)
Member sequence: A0AAF0RV25 (253 AA)
1 235 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01832

Taxonomy

  Name Taxonomy ID Lineage
Phage Lysinibacillus phage phiG2
[NCBI] 		3043671 Kalamavirales > Tectiviridae >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
OQ791408 [NCBI]
CDS location
range 10340 -> 11101
strand +
CDS
ATGGGAGCGTATGATAAATTCATACAGGACATATTACCGTATGCCAAAGAAATAGAAAACAAGTATCATATCCCCACATCGGTAACAATCGGTCAAGCCGTACTCGAATCGGCGGGGGGAACACGAACGCCGAAGGATGTTTATTCCGGAAAAGAATCCTATAACCTTTTTGGGGTAAAGGGTTCGGGGGATAATGGTTCGGTGAAATCGTGGACAACCGAAGTTTATGGTGGAGTATCCCAACGTATCGTAGCAAACTTCCGTTCCTATAGTTCTTGGTATGGTAGTCTTGAAGACTATGCCAAACTATTAACGGGTGCGTCCCGATATGCAGGAGCGTTCAAAACGAACAATCCGTACGACTTTGTATCCGAAGTACGAAAAGCCGGATATGCTACCGACCCGAGTTATACATCAAAGGTTACGAGCATTATGGATAAATACAATTTAACACAATATGACGGGGACAAGTACAAAGGGAAACCAGTCTCCGGAGGAACGGGAGGAGCCACCAAGCCCGTATACGAAAGTGACGACAAAACCACGAAAGAAGAACACGACCGATTATCCCAAGAATCCGAGGAACGGGGACATAGAATTTTCTATATCCCTATTCCGGGGACAGACGGGATTGAAATTTATTCCGGTCAAATGTTTTCCTTCATGTTAATGGCGGTCGGTGTTATTCTCGCTATACTCGCTTTATACTCCATGTTCCTAAAAGATAGTGTGATTATTCAAACGGAAGGAGAACCCGCTTAA

Gene Ontology

Description Category Evidence (source)
GO:0004040 amidase activity molecular function None (UniProt)
GO:0016020 membrane cellular component None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (4LEw1) rather than this protein.
PDB ID
4LEw1
Method AlphaFoldv2
Resolution 88.88
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50