Protein

Protein accession
A0AAF0KCT0 [UniProt]
Representative
4kR5T
Source
UniProt (cluster: phalp2_5637)
Protein name
Hydrolase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MNRTQRAALAVASVALLVPVTSSCAALNAAPISNATANHNPEIEKINWYSPEQRAKEAKRQEQDSKVSSSRSGDAAAAAIAYARTKIGVPYLWGGTGTAAQGGRFDCSGLTQAAYAKAGISIPRVANDQYNTTDVHPSWNELKPGDLVFFGQKGNSRSIHHVGIYIGGGKMLHAPRTGTLIRVNDVHYMSDYFGATRVA
Physico‐chemical
properties
protein length:199 AA
molecular weight:21201,6 Da
isoelectric point:9,54
hydropathy:-0,31
Representative Protein Details
Accession
4kR5T
Protein name
4kR5T
Sequence length
221 AA
Molecular weight
23668,32050 Da
Isoelectric point
9,49698
Sequence
VKVRHRAALAAATASLSALALTGCGSLGDSPVSNAKANKNPAIQEVNSYADGAPRPAPDRADRTKPKEPEKPKVSGEKAKKDPVGTRNDMAPAARSQEIPAWATAINWAQTKLGHKYVWGGESDEEGGFDCSGLMQAAYAKAGVQLPRVANDQYATTNVHPKKSALRPGDLVFYGQTERGIHHVGLYVGSGYMLHAPNSRSKIRFDKISYMSDYYGATRVS
Other Proteins in cluster: phalp2_5637
Total (incl. this protein): 16 Avg length: 198,9 Avg pI: 9,36
Protein ID Length (AA) pI
4kR5T 221 9,49698
2YHFG 199 9,75370
4OarI 200 9,95587
4Yjqd 186 9,41885
6T7Dn 230 6,35394
6TaA2 181 8,84830
6Tcev 199 9,67601
6Tcg2 186 9,17161
6UcGZ 199 9,72623
6Ue6R 197 9,63520
A0A345M6Y6 197 9,66318
A0A386K918 197 9,63443
A0A4D6E0J6 197 9,66318
A0A6M3T5X5 197 9,63488
A0A7T0M1N1 197 9,66318
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_20916
72mid
 3 38,2% 136 1.720E-26
2 phalp2_24984
CFMj
 3 34,2% 149 3.095E-19
3 phalp2_28415
1DMoi
 3 32,0% 150 9.098E-18
4 phalp2_15040
7dnpj
 29 25,0% 160 4.464E-12

Domains

Domains [InterPro]
Disordered region
NLPC_P60
Representative sequence (used for alignment): 4kR5T (221 AA)
Member sequence: A0AAF0KCT0 (199 AA)
1 221 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF00877

Taxonomy

  Name Taxonomy ID Lineage
Phage Streptomyces phage Frankenweenie
[NCBI] 		2969429 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
OQ921725 [NCBI]
CDS location
range 68375 -> 68974
strand -
CDS
GTGAATCGGACCCAGCGAGCGGCCCTGGCGGTCGCCTCCGTGGCGCTGCTCGTGCCCGTCACGTCGTCCTGCGCCGCCTTGAACGCGGCCCCGATCTCGAACGCCACGGCGAACCACAACCCCGAGATCGAGAAGATCAACTGGTATTCGCCGGAGCAGCGGGCCAAGGAGGCGAAGCGGCAGGAGCAGGACTCGAAGGTGTCCAGCTCCAGGTCTGGCGACGCGGCAGCCGCAGCCATCGCGTACGCCCGCACGAAAATCGGAGTCCCTTATCTGTGGGGTGGCACCGGCACGGCCGCGCAGGGTGGCCGGTTCGACTGCTCGGGTCTCACGCAGGCGGCGTACGCGAAGGCGGGGATCTCGATCCCCCGGGTCGCGAACGACCAGTACAACACGACTGACGTGCACCCTTCCTGGAACGAGCTGAAGCCGGGTGACCTGGTCTTCTTCGGCCAGAAAGGGAACTCGCGCTCGATCCATCACGTCGGCATCTACATCGGCGGCGGGAAGATGCTGCACGCACCCCGCACGGGAACGCTGATCCGCGTGAACGACGTGCACTACATGAGCGACTACTTCGGAGCGACGAGGGTGGCCTGA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008234 cysteine-type peptidase activity molecular function None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (4kR5T) rather than this protein.
PDB ID
4kR5T
Method AlphaFoldv2
Resolution 73.65
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50