Protein

Protein accession
A0AAF0JJZ1 [UniProt]
Representative
7s07Z
Source
UniProt (cluster: phalp2_26078)
Protein name
NlpC/P60 domain-containing protein
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MSERTAYLDWVEAQAERGTPYCWPAASNGYLGKGLQRPESPEALDCSGTVTCGLYNATKGRLDWRAMHNAQRLFDELAPTDKPRPGDLAFYGMPGRVTHVMTVVGDGRVVGASGGNSHTLSVELARKAGARVKYRASATYRPDLLGYRVLPVE
Physico‐chemical
properties
protein length:153 AA
molecular weight:16674,7 Da
isoelectric point:8,82
hydropathy:-0,44
Representative Protein Details
Accession
7s07Z
Protein name
7s07Z
Sequence length
172 AA
Molecular weight
18445,73010 Da
Isoelectric point
9,02804
Sequence
MVKPVSTRAAFVSRILDQMHSPYRWNGKGERPDINGPRFFDCSGLVTACYFEAGGPDWRATHNTDRLLAELAPVSESELKTGDLVLYGRNGDASHVMVYVGAGVVVGASGGDHTTRTLADAYARGARVKSEPSVTYRLDLLGFRRLPFVVEVAGALTPSSGIPAVRAPLRAA
Other Proteins in cluster: phalp2_26078
Total (incl. this protein): 53 Avg length: 152,3 Avg pI: 8,50
Protein ID Length (AA) pI
7s07Z 172 9,02804
11DsZ 150 9,55829
1FUkq 155 8,59984
1GXxS 152 8,71343
1NNCV 157 8,64039
1P087 164 6,82741
1Qr9X 161 9,00399
1rrTc 166 7,20232
2irNW 140 9,68994
2jNo0 148 6,49553
4FBwS 154 9,35251
4Hm5e 137 6,07094
4NIFW 138 9,69342
4NOsk 144 9,76324
4OyAN 152 8,92889
4fJ9K 150 9,06066
4fObk 167 8,62963
4fOui 153 9,29855
4fWjw 148 7,78270
4gedf 148 6,64694
4wGLP 150 7,74098
5jbd9 155 7,77116
6PJKF 147 7,84685
6SKPb 146 7,81320
6TiNa 161 6,38935
71XE0 171 7,90262
7C1SR 155 9,33659
7cqSA 112 8,75585
7rStC 150 9,30010
7rSul 150 8,90574
7rSvv 163 9,06659
7s0f5 150 8,68649
7s0fD 150 9,29810
7sFKf 155 9,59633
7sFME 155 9,68375
7vUco 151 9,23215
7wwIn 162 8,92876
7wwJ2 150 9,09547
7wwfq 153 8,49405
7wz7v 150 9,61457
7xEFT 146 9,33852
7xEH0 149 8,81626
7xEIu 153 8,90542
7xEMa 155 9,25129
876Va 141 6,00921
8LLhH 153 8,47555
8iYsZ 146 8,69145
8pOSS 149 8,88885
8pOvX 160 7,71995
MMFs 171 9,15524
Z5Lq 150 5,57860
Q94MP7 153 8,47555
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_3467
4b9No
 1 31,1% 154 3.861E-32
2 phalp2_29063
6QfOM
 447 31,9% 144 6.533E-28
3 phalp2_4609
4iAfK
 3 31,2% 144 7.222E-26
4 phalp2_7249
3QzVS
 32 31,3% 137 4.247E-24
5 phalp2_1556
40W37
 2 29,7% 178 4.247E-24
6 phalp2_6899
2tG8S
 2 33,1% 148 2.781E-23
7 phalp2_33743
ZDk4
 1 33,1% 151 3.803E-23
8 phalp2_21816
4gVTK
 1 25,5% 141 8.693E-22
9 phalp2_17633
6J1p0
 6 32,4% 145 2.221E-21
10 phalp2_27807
7Tiwg
 23 28,0% 157 4.151E-21

Domains

Domains [InterPro]
NLPC_P60
Disordered region
Representative sequence (used for alignment): 7s07Z (172 AA)
Member sequence: A0AAF0JJZ1 (153 AA)
1 172 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF00877

Taxonomy

  Name Taxonomy ID Lineage
Phage Myxococcus phage Mx9
[NCBI] 		235265 Myxoctovirus >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
OQ709411 [NCBI]
CDS location
range 8844 -> 9305
strand +
CDS
ATGAGCGAGCGCACCGCGTACCTGGATTGGGTAGAGGCGCAGGCCGAGCGCGGCACCCCATACTGCTGGCCGGCCGCCTCTAACGGCTACCTGGGCAAGGGGCTCCAGCGTCCCGAGTCGCCCGAAGCCCTCGACTGCTCCGGCACCGTGACGTGTGGCCTCTACAATGCCACCAAGGGCCGGCTGGACTGGCGGGCCATGCACAACGCCCAGCGCCTCTTCGACGAGCTCGCGCCCACCGACAAGCCCCGACCCGGGGACCTGGCCTTCTACGGCATGCCGGGCCGCGTGACGCACGTCATGACGGTGGTGGGTGACGGGCGCGTCGTCGGAGCGAGCGGTGGCAACAGCCACACGCTCTCCGTCGAACTCGCGAGGAAGGCCGGGGCGCGGGTGAAATACCGCGCCAGCGCCACCTACCGTCCGGACCTGCTGGGCTACCGGGTTCTGCCAGTGGAGTGA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008234 cysteine-type peptidase activity molecular function None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (7s07Z) rather than this protein.
PDB ID
7s07Z
Method AlphaFoldv2
Resolution 89.07
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50