Protein

Protein accession
A0AAF0GLD9 [UniProt]
Representative
7i7AZ
Source
UniProt (cluster: phalp2_30716)
Protein name
Endolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MTNECSRPKDSAIMTAALKPAYNERIQWSPNATPRGGVRNRLGVGHTQEGNGTAASLANYLCQSSSGVSYHYTLDNDRNVVAVVDTDWYSWSVLSANPFTINYCFAGSRAAWTRQQWLDNMGNAIEILAWLWVEDAKKYDLQPWCISNADVGAGKQGFTDHAGITYGLGIGNHTDLGRDFPFDVLAGHIDRFVNGVSEPVPDITAIEYCRAANEWLGSKVTTNREETAPDGVGKFVHYERGSIYWQPDMPDGKAIAVPAEIFAKWSSENWEVGYLGYPRGPHLVLPPYNRSDGTPVPGGTVQSFQGGTVYVSELGSYGVRGLIRDRYASLGYETKSLGWPTGDEEPWGDAKYGGMFQSFAHGYIIWINDGNSTIAFNKENKILLPIENQAPPGPAEPQPVGYVATPEENRATPVDGMIGGCSHFANPDDPSTRGKFMGLSGEPADKPTDQWYAAMRFNYCRIQDDPKKPFWVKPVSGTSDLELKRYLPNRRLKVTNLANGKAVVVRPADWGPGAWAKPGGEKYRVVDLSATALSKIGASTDDKVVVEWVDPATPLGPIA
Physico‐chemical
properties
protein length:559 AA
molecular weight:61183,7 Da
isoelectric point:5,43
hydropathy:-0,44
Representative Protein Details
Accession
7i7AZ
Protein name
7i7AZ
Sequence length
553 AA
Molecular weight
60208,51740 Da
Isoelectric point
5,84966
Sequence
MPKPAYDERIQWSPHHHARPVRDIRFGAIHTQEGPGTAASLANYLCNPSSQVSYHYTVDNDRNVVAVVDTDDASWSVGNANGRVVNVCFAGSFVRWSKQEWLDRMGNAIEIAAYLQVLDARKYGFDPVVRGWDELRSKRNGLTDHRGINMAVLGGPGHTDVGDNFPWDVYAGHVDRFVREGTDVVPAGPDPALPTVIEQCRAANDWLGAKVSDGREVTTPDGAGRFAQYEHGWVYWSPTVDEGRAAYAIPFGPIGDAFAATGYEAGRLGYPRGPKLDLLPFTRSTGRPVAGGVVQAFQHGTVYDRAEEPTTVNAYIVQGTIREKYASLDYERGELGWPLSDEMDWAEGKWQRFEHGVVYWTAATNSAIAFVGETGKVRPISPPRAPVAPAPAPPAPAGYVPSDDERQLTPRDNKWVGGISHFATPGDASTRGRNMGVSGEPADNPRDPFYCAMRWGYVGLAQHRTGTPGWVGPVDRTDITPAEKMRLKTVLASKRVKVTGGGRSVVLRPADWGPAPTKRVVDVSPTVLAGLGLDTDDEVTVEWVAPTTPLGFL
Other Proteins in cluster: phalp2_30716
Total (incl. this protein): 2 Avg length: 556,0 Avg pI: 5,64
Protein ID Length (AA) pI
7i7AZ 553 5,84966
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_28062
7ebmV
 12 43,8% 363 6.998E-92
2 phalp2_35332
7m5Au
 49 42,6% 382 1.640E-86
3 phalp2_30754
7C7wA
 28 40,9% 381 5.974E-80

Domains

Domains [InterPro]
Ami2
LGFP
Unannotated
Representative sequence (used for alignment): 7i7AZ (553 AA)
Member sequence: A0AAF0GLD9 (559 AA)
1 553 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01510, PF08310

Taxonomy

  Name Taxonomy ID Lineage
Phage Rhodococcus phage Trogglehumper
[NCBI] 		3038381 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
OQ709222 [NCBI]
CDS location
range 44419 -> 46098
strand +
CDS
ATGACGAACGAATGCTCCCGACCGAAGGACAGCGCCATCATGACTGCAGCTCTCAAGCCTGCGTACAACGAGCGAATCCAGTGGTCCCCGAACGCAACTCCTCGCGGAGGTGTCCGTAACCGTCTCGGCGTCGGACACACCCAGGAGGGCAACGGCACGGCCGCCTCGCTCGCGAACTACCTGTGCCAGTCCAGCTCTGGGGTCTCCTATCACTACACGCTCGACAACGACCGCAACGTCGTCGCCGTCGTCGACACCGACTGGTACAGCTGGTCGGTCTTGAGCGCCAACCCCTTCACGATCAACTACTGCTTCGCAGGCTCGCGCGCCGCGTGGACTCGCCAGCAGTGGCTCGACAACATGGGCAACGCGATCGAGATCCTGGCCTGGCTCTGGGTCGAGGACGCCAAGAAGTACGACCTGCAGCCCTGGTGCATCTCCAATGCCGATGTCGGCGCAGGCAAGCAAGGCTTCACCGACCACGCAGGCATCACGTACGGGCTGGGCATCGGCAACCACACCGACCTCGGCCGCGACTTCCCGTTCGACGTCCTGGCCGGTCACATCGACCGCTTCGTCAACGGTGTCAGCGAGCCGGTCCCGGACATCACGGCGATCGAGTACTGCCGCGCCGCCAATGAATGGCTGGGCAGCAAGGTCACCACGAACCGCGAGGAGACCGCGCCGGACGGCGTCGGCAAGTTCGTGCACTACGAGCGTGGCTCGATCTACTGGCAGCCGGACATGCCGGACGGCAAGGCCATTGCCGTGCCCGCCGAGATCTTCGCCAAGTGGAGTTCCGAGAACTGGGAGGTCGGCTACCTCGGCTACCCGCGCGGCCCGCACCTGGTTCTGCCGCCGTACAACCGCAGCGACGGCACGCCCGTCCCCGGCGGCACCGTGCAGTCCTTCCAGGGTGGCACGGTCTACGTCAGCGAGCTTGGCTCGTACGGCGTGCGCGGCCTGATCCGCGATCGCTACGCCAGCCTCGGCTACGAGACCAAGTCTCTCGGCTGGCCCACGGGCGACGAAGAGCCCTGGGGAGATGCCAAGTACGGCGGCATGTTCCAGAGCTTCGCGCACGGCTACATCATCTGGATCAACGACGGCAATTCCACGATCGCGTTCAACAAAGAGAACAAGATCCTGCTGCCGATCGAGAACCAGGCACCACCCGGGCCGGCCGAGCCCCAGCCGGTCGGCTACGTGGCCACGCCGGAGGAGAATCGCGCCACCCCTGTGGACGGGATGATCGGCGGCTGTTCGCATTTCGCCAATCCGGACGACCCCTCCACGCGAGGCAAGTTCATGGGATTGTCCGGCGAACCGGCCGACAAGCCGACTGATCAGTGGTACGCCGCGATGCGGTTCAACTACTGCCGCATCCAGGACGACCCGAAGAAGCCGTTCTGGGTCAAGCCGGTGTCGGGTACCTCGGATCTCGAACTCAAGCGCTATCTGCCGAATCGCCGCCTCAAGGTGACCAACCTGGCCAACGGCAAGGCCGTCGTCGTGCGTCCTGCCGACTGGGGGCCGGGCGCCTGGGCCAAGCCGGGCGGCGAGAAGTACCGCGTCGTCGATCTCTCGGCCACCGCGCTGAGCAAGATCGGCGCGAGCACTGACGACAAGGTCGTCGTCGAATGGGTCGACCCGGCAACCCCGCTGGGTCCGATCGCGTAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (7i7AZ) rather than this protein.
PDB ID
7i7AZ
Method AlphaFoldv2
Resolution 81.83
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50