Protein

Protein accession
A0AAE9VA87 [UniProt]
Representative
7wEyl
Source
UniProt (cluster: phalp2_12324)
Protein name
Peptidase M23 domain-containing protein
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MIDLAIFNCPVEKARLTSKFGWRDIGRGREWHQGVDLASPVAGAKVPVYAAADGEVSYAAPLSTYGNSVRIVHKIDGVTYETNYAHLDRIMVKRLERVKKGQQIGVMGNTGGSFGVHLHFEIHVGRYAAGQPNAKDPMNWITLGSCVPLGSQKEGELTMSQYNELKKEIAELRKLVEGKIDKPSPRQAGKNHAEDWKWGKDNKITDGNNPQDYATREQVLTMLNRLENKIKK
Physico‐chemical
properties
protein length:232 AA
molecular weight:25884,2 Da
isoelectric point:9,28
hydropathy:-0,60
Representative Protein Details
Accession
7wEyl
Protein name
7wEyl
Sequence length
224 AA
Molecular weight
25079,42260 Da
Isoelectric point
9,56538
Sequence
MVSFISPVRDARLTSKFGWRNIGFGQEWHQGVDLASTGKVPIYASATGIISRAQALSSYGNVVMIKHIINGKIYETNYAHLDSSCVHVGQRVLQGQQIGVMGKTGRAYGIHLHFEIHEGLWAKGQPNAVDPMKFISLTNTILANKGELTMSQYTELLSKIKELEEAITTKQAIIPSRKPAKIHNTAWEWLRNKGITDGSNPQNFLTREQFATMLKRYDDSINKH
Other Proteins in cluster: phalp2_12324
Total (incl. this protein): 24 Avg length: 229,3 Avg pI: 9,50
Protein ID Length (AA) pI
7wEyl 224 9,56538
191gm 219 9,34361
1abkC 227 9,49789
1aeW9 227 9,62843
1buD3 227 9,55623
1dEFi 228 9,51858
1dEml 219 9,18450
1epF3 227 9,62876
1mKf1 290 9,21584
1msEw 227 9,51793
2ekvG 243 9,42652
2g69W 227 9,58840
4E67g 211 9,81713
78QVM 241 9,21706
79KEO 224 9,49789
7cNwW 227 9,62876
7dNkY 227 9,58840
7det7 223 9,69555
7lCRY 219 9,58485
7plrZ 219 9,30048
7pzuc 252 9,79051
7reZy 224 9,56074
7rt3x 219 9,41524
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_12806
8u7FM
 2 39,0% 141 2.580E-26
2 phalp2_25322
8sm9b
 10 38,5% 140 1.108E-22
3 phalp2_9313
7uik1
 1 31,6% 158 5.301E-20
4 phalp2_1609
82pcH
 10 36,4% 151 2.469E-19
5 phalp2_8822
2sKc0
 6 35,2% 136 3.358E-19
6 phalp2_25537
3nGXJ
 39 26,8% 216 1.561E-18
7 phalp2_3101
40Xl7
 22 29,0% 162 5.326E-18

Domains

Domains [InterPro]
PET_M23
Disordered region
Representative sequence (used for alignment): 7wEyl (224 AA)
Member sequence: A0AAE9VA87 (232 AA)
1 224 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01551

Taxonomy

  Name Taxonomy ID Lineage
Phage Lysinibacillus phage LC76P1
[NCBI] 		2968682 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
OP172811 [NCBI]
CDS location
range 79999 -> 80697
strand -
CDS
ATGATTGACTTGGCTATTTTTAATTGTCCAGTAGAGAAAGCCAGACTTACTAGCAAATTTGGATGGCGAGATATCGGTCGTGGACGTGAATGGCATCAAGGAGTAGATTTAGCGTCTCCAGTAGCAGGAGCAAAAGTTCCTGTGTATGCGGCGGCTGACGGTGAGGTATCTTATGCGGCTCCTCTCAGCACGTATGGCAACTCTGTACGTATCGTTCATAAGATTGACGGAGTGACATACGAAACTAACTATGCTCACTTGGATAGAATAATGGTTAAGCGCCTTGAGAGAGTTAAGAAAGGTCAACAAATCGGAGTCATGGGTAACACAGGTGGAAGTTTCGGTGTGCATCTACACTTCGAGATTCATGTTGGTAGATACGCCGCAGGTCAGCCTAACGCCAAAGACCCGATGAATTGGATTACACTAGGTTCATGTGTACCACTAGGAAGTCAAAAGGAAGGGGAGCTAACTATGTCACAGTATAATGAATTAAAAAAAGAGATTGCAGAATTACGTAAATTAGTTGAGGGTAAAATCGATAAACCGTCACCGCGTCAAGCAGGCAAAAATCACGCCGAAGATTGGAAGTGGGGTAAGGATAACAAAATCACAGATGGCAACAATCCACAAGACTATGCTACTCGTGAACAAGTCCTTACAATGCTTAATCGATTGGAGAATAAAATCAAAAAGTAA

Gene Ontology

Description Category Evidence (source)
GO:0004222 metalloendopeptidase activity molecular function None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (7wEyl) rather than this protein.
PDB ID
7wEyl
Method AlphaFoldv2
Resolution 83.02
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50