Protein

Protein accession
A0AAE9V2G8 [UniProt]
Representative
7wNe2
Source
UniProt (cluster: phalp2_38225)
Protein name
MurNAc-LAA domain-containing protein
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MVIASSGAGHGGRKTNGSWMDPGAVGNGYSEADFTRLINSKIIAATGVLDTSDNVATSVNANINNIAANINRGPNGWAISNHLNSFDEKSTGVEVLYGSKDSEPMAAKLSAAIAKALGLPNRGAKDGTWLGIARGSGAGKKVLLIEWAFVSNPNDMKALSSKLDAAVNAMLEVFGYSTGTTNKPAPTPAQPETTNSLGGFEMYIYWQPQAKGNVSDAFAVWGNKRFYLPTQARVTHFKNLVKDMTGKECREYRWPRGSDQIKNAEASTDLAK
Physico‐chemical
properties
protein length:272 AA
molecular weight:28948,2 Da
isoelectric point:9,18
hydropathy:-0,37
Representative Protein Details
Accession
7wNe2
Protein name
7wNe2
Sequence length
328 AA
Molecular weight
34483,41470 Da
Isoelectric point
9,79973
Sequence
MSIVSSGAGHGGKKTGSTWFDPGAGGHGYNEADFTRKINEKILTITKAKDTTDNAGTSANSNLGNITAKINAGADGWALSNHLNAFNGTAHGVEVLYGSPSSKGKAEEMAAAISKATGLTNRGAKDGSWLYLARNSYPGKKVLLIEWAFVDNKSDMDKLVKNLDKAIAAMLACFGYKTSSPSESKPTTGLKTGDTVKVTGNLYKDADGSGKSSKSRGKSGKIDKIAKGKKKPYHVNGLGWAAATDLNANSQNKPSTSKTKTVTIDKLNVYTSQSLSSPIVKTASGYRILKKGTKVKVTATANNGQSVHGSKHWSEVDGFGWVPSVYLK
Other Proteins in cluster: phalp2_38225
Total (incl. this protein): 3 Avg length: 308,7 Avg pI: 9,58
Protein ID Length (AA) pI
7wNe2 328 9,79973
7wNdh 326 9,77761
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_14956
ooF5
 39 31,5% 257 1.954E-14
2 phalp2_36719
6eCmw
 993 32,7% 217 1.538E-11
3 phalp2_23331
5tGuH
 43 35,0% 208 6.448E-10
4 phalp2_12323
7wjSB
 3 29,7% 225 4.776E-09
5 phalp2_37478
366XE
 2 24,4% 336 3.516E-08
6 phalp2_24413
4m1OU
 1246 29,1% 223 1.875E-06

Domains

Domains [InterPro]
Ami3
Unannotated
Unannotated
Representative sequence (used for alignment): 7wNe2 (328 AA)
Member sequence: A0AAE9V2G8 (272 AA)
1 328 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01520

Taxonomy

  Name Taxonomy ID Lineage
Phage Enterococcus phage EC99P2
[NCBI] 		2968636 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
OP172783 [NCBI]
CDS location
range 37082 -> 37900
strand -
CDS
ATGGTCATCGCATCAAGTGGCGCCGGACACGGCGGACGTAAAACCAACGGTTCTTGGATGGACCCGGGAGCCGTTGGGAACGGGTATAGCGAAGCTGACTTTACACGCTTAATCAACAGCAAGATCATTGCCGCAACGGGCGTGCTAGATACGTCCGACAACGTCGCGACATCGGTCAACGCAAACATTAATAACATCGCCGCGAACATCAATCGTGGACCTAACGGGTGGGCTATTTCAAACCACCTTAATTCCTTCGATGAAAAATCGACGGGGGTCGAAGTGTTATACGGTTCTAAAGACAGCGAACCGATGGCGGCGAAGTTATCAGCGGCAATCGCTAAGGCATTAGGCTTACCGAATCGCGGCGCTAAAGATGGCACGTGGTTAGGTATCGCACGCGGATCGGGAGCGGGCAAAAAGGTATTGCTTATCGAGTGGGCTTTTGTCAGCAACCCGAACGACATGAAAGCGTTGAGTTCTAAACTAGACGCGGCCGTCAATGCTATGCTCGAAGTATTCGGTTACTCGACCGGTACGACGAACAAACCGGCACCAACGCCGGCACAACCAGAAACTACTAACTCATTAGGAGGGTTCGAAATGTATATTTATTGGCAACCACAAGCAAAAGGCAATGTAAGCGACGCGTTCGCAGTATGGGGTAACAAACGTTTCTACTTGCCAACGCAAGCACGGGTAACGCACTTCAAAAACTTGGTCAAAGACATGACAGGTAAAGAGTGCCGCGAATATCGTTGGCCGCGCGGATCAGATCAGATCAAAAACGCGGAAGCAAGCACCGACTTAGCAAAATAA

Gene Ontology

Description Category Evidence (source)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (7wNe2) rather than this protein.
PDB ID
7wNe2
Method AlphaFoldv2
Resolution 90.20
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50