Protein

Protein accession
A0AAE9URC1 [UniProt]
Representative
5OOrY
Source
UniProt (cluster: phalp2_3780)
Protein name
MurNAc-LAA domain-containing protein
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MKPIVILDNGHGEETAGKRSPVWGDGSQLFEWEFNRDIVRRIAAKLDDLGIGYEILTPETNDVSLPERCRRANEIYRNYNEMAFLVSVHANAGGGTGWEVYTSPGETKADVIATVFAEEAQRVFVPDGWRMRFDYSDGDPDKEAAFYILKYTSCPAILTENFFMDTEKDCRFIMSDAGREQIADMHVAAIKRVVRI
Physico‐chemical
properties
protein length:196 AA
molecular weight:22196,7 Da
isoelectric point:4,84
hydropathy:-0,37
Representative Protein Details
Accession
5OOrY
Protein name
5OOrY
Sequence length
105 AA
Molecular weight
11637,00640 Da
Isoelectric point
5,06063
Sequence
MNAQGWSVYTSKGQTSADKLATCIYEVAESKLKPLGKKLRPDNSDGDPDQEANYYVLSKTACPACLTENMFMDNKEDATWLLSSEGRNIITDIHVEGIKKYIASL
Other Proteins in cluster: phalp2_3780
Total (incl. this protein): 15 Avg length: 123,5 Avg pI: 5,70
Protein ID Length (AA) pI
5OOrY 105 5,06063
3F7o 127 5,88826
3iYWH 69 6,52395
3o4Yx 109 5,58570
40eOa 133 6,87271
4kfgd 81 8,60100
4kxTI 104 4,31518
5STuy 106 4,78672
6tgQm 94 7,11638
7DI1a 136 4,61757
8k39o 96 4,66724
8mDSI 134 5,33328
8tT9N 132 5,28321
A0A8S5VW10 231 6,06832
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_13020
42XXy
 16 53,0% 100 5.680E-33
2 phalp2_10309
1kAKU
 14 48,2% 85 9.161E-24
3 phalp2_11209
6km9A
 8 51,3% 72 1.328E-20
4 phalp2_3633
4SuvT
 23 30,3% 99 8.246E-12
5 phalp2_39633
6JJjF
 2 27,2% 99 5.493E-11
6 phalp2_12459
y0JW
 12 24,6% 81 2.764E-07
7 phalp2_13307
3CKaa
 17 29,4% 95 2.269E-05
8 phalp2_35857
4KnyH
 4 24,5% 106 5.827E-05

Domains

Domains [InterPro]
Ami3
Representative sequence (used for alignment): 5OOrY (105 AA)
Member sequence: A0AAE9URC1 (196 AA)
1 105 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01520

Taxonomy

  Name Taxonomy ID Lineage
Phage Alistipes phage AS73P1
[NCBI] 		2968529 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
OP172640 [NCBI]
CDS location
range 9572 -> 10162
strand +
CDS
ATGAAACCTATTGTTATTTTAGACAACGGACACGGCGAAGAAACCGCCGGGAAACGTTCCCCGGTTTGGGGCGACGGGTCGCAACTATTTGAATGGGAGTTTAACCGGGACATTGTACGCCGTATTGCCGCCAAATTGGACGATTTGGGGATTGGGTACGAGATATTGACGCCGGAAACAAACGACGTGTCATTGCCGGAACGTTGCCGCCGTGCAAACGAGATTTACCGCAATTACAACGAAATGGCGTTTTTGGTATCAGTCCACGCCAACGCCGGGGGCGGTACGGGTTGGGAGGTTTACACGTCGCCCGGCGAAACGAAAGCCGATGTTATCGCCACGGTATTTGCCGAGGAAGCACAACGGGTATTTGTCCCGGACGGTTGGCGTATGCGGTTCGATTATTCGGACGGCGACCCGGATAAGGAAGCGGCGTTTTATATTCTCAAATATACGAGTTGCCCGGCAATCCTTACGGAAAACTTTTTTATGGATACCGAAAAAGATTGCCGTTTCATAATGAGCGACGCCGGACGGGAACAAATAGCCGATATGCACGTTGCCGCAATTAAAAGAGTTGTACGGATATGA

Gene Ontology

Description Category Evidence (source)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (5OOrY) rather than this protein.
PDB ID
5OOrY
Method AlphaFoldv2
Resolution 96.78
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50