Protein

Protein accession
A0AAE9UQQ1 [UniProt]
Representative
5URSo
Source
UniProt (cluster: phalp2_19895)
Protein name
MurNAc-LAA domain-containing protein
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MAKYNVHAGHCPQGKGASGAVGFLKESVEDRKVKEKVIRLLKSQGHTVYDCTCDTAESQSGCLDKIVSKCNQHSVKRDISIHLNSGRNDQKGDGSTGGVEVYVYSDCSDAYGDAERICQEVSKTLGVANRGVKINTSLRVLRTTKSPSLLVECCFVDDKDDYMHWNAGKCAAAIVKGLTGKSTGSTTDKKKEKAPAKKGTPKKTESSTPSKKEIIKDLQAACNKQGYSNQKVDGISGKNTLAGCPVLRSGASGEITKCMQRLLKYVHGYDLGKYGCDGDFGNATKAAVKKFQKAKGLEPDGIVGKKTWKKLMGI
Physico‐chemical
properties
protein length:314 AA
molecular weight:33740,2 Da
isoelectric point:9,33
hydropathy:-0,60
Representative Protein Details
Accession
5URSo
Protein name
5URSo
Sequence length
360 AA
Molecular weight
40783,66290 Da
Isoelectric point
8,13090
Sequence
MVGVLFIKNYCAIARKGVNMGTYNVHAGHCPQGQGASGAVGILQESVEDRIVKNEVIRLLRADGHTVYDCTCDENTTKQGCLNKIVAKCNQHDVDFDMSVHLNSGRNDYGGDGSAGGVEVIIYDDTTKEVAERICANIATELGIRNRGVKYNKSLFVLKKTVSPAFLIECCFVDDADDAKAWDAKRCAKAIVEGVLNRKMATEKYTMHTFGANRKIYDNDRKEYLKDRWCLYKGKYYYCGKDEYLLTGWQTNVDGRKKVYFIAPDWHLHAGWLSFGSTYYYMHSNGEMATGWTRINGDTYYFGDDGIRRTGWQTIDGKKYWFDAKTGKMLKGRITFGSTWYYLSETDGHLMHTKDDGSLY
Other Proteins in cluster: phalp2_19895
Total (incl. this protein): 85 Avg length: 317,8 Avg pI: 8,03
Protein ID Length (AA) pI
5URSo 360 8,13090
13z9j 342 7,59383
1eryr 262 9,62418
1n3sC 305 7,08017
1n83f 308 5,72843
3kadG 258 9,67330
3knK0 258 9,67330
3lHTK 292 9,55616
3m9Z7 294 9,57931
3qIGu 294 9,62702
3rRrn 342 8,87738
3rhlc 294 9,57912
3rice 362 8,45788
3rpx6 321 6,91039
3tHNW 262 9,55481
3taa6 258 9,67330
3vtwC 325 7,57598
3wY7L 352 9,03410
3wx1K 352 9,20210
3wyyO 292 9,47680
3xMyu 306 6,78467
3xquP 258 9,63553
4z4Ye 321 7,66448
5C0EI 347 8,43364
5KEB8 321 6,45904
5KOkc 343 8,41475
5LCld 359 8,72207
5LksU 325 5,70916
5QGmR 321 6,45619
5Qq0W 251 9,08735
5RiWF 342 8,56516
5Sn1X 277 8,42197
5T9e1 294 9,52935
5TOmy 394 6,07196
5Xynl 322 8,88370
61lU1 345 6,54350
62YHq 380 6,01109
62ibu 345 7,53483
66SVP 345 6,54526
67ML4 345 6,54202
67dWV 373 8,55755
68KAl 365 8,56825
68hBg 294 9,51645
68un9 284 7,08972
69HfS 321 7,58155
69vO6 321 8,37472
6adhu 342 8,70286
6bj37 394 5,67773
6gSGx 345 6,94836
6hEu6 305 6,36292
6j1wJ 294 9,55333
6ja8w 290 9,22899
6l2s0 332 9,02759
6ncf7 345 6,54350
6qA8o 292 9,52915
6rSJG 308 5,71075
6s0IJ 330 8,74715
6vOE1 343 5,65061
70ltT 258 9,60813
70ruh 258 9,67330
76NjB 369 6,55367
7UnTq 262 9,66151
7XsbC 301 8,74528
7YLk1 262 9,51645
7bdu6 321 6,90943
7cu87 333 5,15123
7ompf 357 5,18181
7plGr 339 6,11141
7ppN2 333 5,00083
7qtTr 321 8,24971
7s6Xk 294 9,57931
7tDgY 324 8,30174
7yGDm 294 9,57931
7ypfA 321 8,49502
85fbH 342 5,93356
8eAIB 343 5,83176
8hMKB 365 8,64800
8jSTd 357 5,38751
8knjv 345 6,45915
8tT1m 294 9,55313
opXh 253 9,72759
A0A9Y1MS15 314 9,32750
A0AAE9US89 314 9,32750
A0AAU8B1W4 270 8,64026
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_1101
7tqzR
 6 33,6% 294 2.376E-61
2 phalp2_12323
7wjSB
 3 32,2% 310 1.947E-57
3 phalp2_18589
7mHjP
 38 25,3% 272 1.211E-33
4 phalp2_2533
65Ish
 36 27,4% 302 7.912E-30
5 phalp2_25313
8kQxh
 1 19,7% 253 8.124E-18
6 phalp2_29154
7mKv1
 17 21,9% 283 2.449E-08

Domains

Domains [InterPro]
Ami3
Choline_bind_3
Representative sequence (used for alignment): 5URSo (360 AA)
Member sequence: A0AAE9UQQ1 (314 AA)
1 360 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01520, PF19127

Taxonomy

  Name Taxonomy ID Lineage
Phage Anaerostipes phage AC844P2
[NCBI] 		2968533 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
OP172636 [NCBI]
CDS location
range 20777 -> 21721
strand -
CDS
ATGGCGAAATATAATGTACACGCCGGGCATTGTCCGCAGGGAAAAGGAGCATCTGGTGCAGTCGGATTTTTAAAGGAATCCGTGGAAGATAGGAAAGTAAAAGAAAAAGTGATCAGACTGTTAAAATCACAAGGGCACACAGTCTATGATTGCACATGCGATACGGCAGAAAGCCAGAGCGGATGTCTGGATAAGATCGTAAGCAAATGCAACCAGCACAGTGTTAAAAGAGATATCTCTATTCATCTGAATAGTGGCAGGAATGATCAGAAGGGCGATGGATCAACAGGAGGAGTTGAGGTTTATGTATACTCCGACTGCTCTGATGCCTACGGTGATGCGGAAAGGATCTGTCAGGAAGTCTCAAAAACACTAGGTGTTGCAAACCGTGGAGTAAAGATAAATACATCGTTGCGTGTTTTGAGGACTACCAAGTCACCATCCTTATTAGTCGAATGCTGCTTCGTGGATGACAAAGACGACTATATGCACTGGAACGCAGGGAAATGCGCAGCAGCTATTGTAAAGGGGCTTACCGGAAAAAGTACTGGTTCTACGACAGATAAAAAGAAAGAAAAGGCTCCGGCGAAGAAAGGTACACCGAAGAAAACAGAGTCCTCTACACCAAGCAAAAAGGAGATTATAAAAGACCTACAGGCAGCTTGTAACAAACAAGGGTATAGCAATCAGAAAGTAGACGGCATTTCCGGTAAGAACACTCTGGCCGGGTGCCCAGTACTCCGATCAGGGGCATCCGGAGAGATCACAAAGTGTATGCAGCGATTGTTAAAGTATGTTCACGGATATGATCTTGGAAAATATGGATGCGATGGCGACTTTGGCAATGCGACCAAGGCGGCAGTAAAGAAGTTCCAGAAAGCGAAAGGACTTGAGCCAGATGGAATCGTAGGGAAGAAGACCTGGAAGAAGTTGATGGGAATATAG

Gene Ontology

Description Category Evidence (source)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (5URSo) rather than this protein.
PDB ID
5URSo
Method AlphaFoldv2
Resolution 92.49
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50