Protein

Protein accession
A0AAE8Y9A5 [UniProt]
Representative
PX4F
Source
UniProt (cluster: phalp2_35529)
Protein name
Endolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MQLTWPVIATITQQFATNPNNIQPNGHTGMDFAVAVGTSVKASGPGTVVWADWATKLSASNPWWIAPAYAGIVVVIDHGNGMLTLYAHLNSTHLNIGNKVTQGQEIGKSGNTGLSSGPHLHFEVIGWPLQPYNNFYGRLNPNLYVKSATPATVALKANQRRVGTSNVNLRAGASTTSKILRIIPANSIETFTGYYNGERVNGNNLWYRDAQGFAHSAGFTTVSATGLPNTTPAPAPVLKANQRLVGADNTNLRSAASTTGKVIKVLPAKSTMTATGYVIGETVKGINVWYKNDVGYAWAGGFTSQATTGLTNVTPKPTPAPAPKPIPAPTPAPAPTPAPVAPKTTGDSKANFRSAPSTTGSITKTLEAKTAYPEFTVYTKGEAVENNDIWFTDAKQSGYAWSGAFTDPKPSANMVLVAAPAKPEGYSFDKDFDFVEYKPAHITNVMRAVDNPDEVVFPPYPEKSVIHQFDAKAKNPSLDGVINHFQTERPGNETSAHFGISGDRIVQFVSLKDRAYHAGKVGNDYIGIETDPQQDAATIESTKKLLRALKAKYGYELITVLHKDVPGNTTNCGVEINLENYELNSVSPTPVPPIIVVPEPTPAPTPAPTPAVDEEAVIDAFLAHLKEEFFKTR
Physico‐chemical
properties
protein length:633 AA
molecular weight:67775,4 Da
isoelectric point:8,23
hydropathy:-0,30
Representative Protein Details
Accession
PX4F
Protein name
PX4F
Sequence length
280 AA
Molecular weight
30581,25080 Da
Isoelectric point
6,49769
Sequence
KTGPDVVNIRKEPNSTSAILGQIPPNTIQSFVGYVVGEKIGNYDVWYKGTTGYVWCGAFTTQSMAGLANVTPKPPVVTPPVTTPTAYSFQKDFDFVEYIPAAINNLNVGNFPDKPEKVVIHQFGTLGVDTLNSTVNTFTNNGLERVASSHFVVSGKRIIQMVSLKDRAYHAGSVGNNYVGIETDPAQDADTIASTKKLLAALKAKYGYELPKTLHKDVPGNSTNCGASIKLSNYDLDPVIVIPTPDPEPKPVERSEEEIIEEFLAWFTKNLKQGFLNRKN
Other Proteins in cluster: phalp2_35529
Total (incl. this protein): 6 Avg length: 462,0 Avg pI: 7,58
Protein ID Length (AA) pI
PX4F 280 6,49769
11DFn 218 5,03090
A0A5J6TPW4 553 8,54214
A0A5J6TQF6 553 8,54214
A0AA96GZT4 535 8,61396
Similar Clusters

No similar clusters were found for representative PX4F.

Domains

Domains [InterPro]
Unannotated
Ami2
Disordered region
Representative sequence (used for alignment): PX4F (280 AA)
Member sequence: A0AAE8Y9A5 (633 AA)
1 280 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01510

Taxonomy

  Name Taxonomy ID Lineage
Phage Arthrobacter phage Atuin
[NCBI] 		2885972 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
OK040794 [NCBI]
CDS location
range 98423 -> 100324
strand +
CDS
ATGCAATTGACATGGCCCGTAATCGCTACGATCACTCAACAGTTCGCAACAAACCCCAATAACATCCAACCAAACGGTCACACCGGCATGGACTTTGCCGTAGCTGTAGGAACCTCTGTAAAGGCCTCTGGTCCCGGAACCGTCGTCTGGGCTGACTGGGCTACCAAGCTCTCAGCATCCAACCCTTGGTGGATCGCTCCTGCCTATGCAGGTATCGTCGTCGTCATCGACCACGGCAACGGAATGCTTACACTCTACGCGCACCTGAACAGCACACATCTGAATATCGGAAACAAGGTAACACAAGGTCAGGAAATCGGCAAGTCCGGAAACACGGGACTCTCCAGCGGTCCTCACCTCCATTTCGAGGTCATCGGATGGCCTCTACAGCCGTACAACAACTTCTACGGGCGTCTGAACCCGAACCTGTACGTCAAGTCCGCTACACCCGCCACAGTCGCTCTCAAGGCCAACCAGCGCCGCGTAGGAACCTCCAACGTGAACCTCCGTGCCGGAGCCAGCACGACATCAAAGATCCTCCGAATCATTCCGGCCAACTCCATTGAGACCTTCACCGGATACTACAACGGAGAGCGTGTCAACGGAAACAACCTCTGGTACCGTGACGCACAGGGATTCGCCCACAGCGCCGGATTCACAACGGTATCTGCAACCGGTCTTCCAAACACGACACCGGCTCCGGCCCCTGTCTTGAAGGCCAATCAGCGCCTCGTCGGTGCCGACAATACAAACCTTCGTTCGGCGGCGTCCACTACAGGTAAGGTCATCAAGGTTCTTCCAGCCAAGAGCACCATGACAGCAACCGGATACGTCATCGGTGAGACCGTCAAGGGCATCAACGTCTGGTACAAGAACGATGTAGGATATGCGTGGGCTGGAGGATTCACCTCACAGGCCACTACAGGATTGACAAACGTCACGCCTAAGCCTACACCGGCTCCTGCTCCTAAGCCTATACCAGCGCCAACCCCTGCTCCGGCACCTACGCCAGCACCAGTGGCCCCAAAGACTACTGGAGATTCCAAGGCAAACTTCCGCAGCGCCCCATCCACAACGGGATCGATCACGAAGACACTGGAAGCCAAGACGGCCTACCCAGAGTTCACGGTCTACACCAAGGGTGAAGCTGTAGAGAACAACGATATTTGGTTCACTGACGCAAAGCAGTCCGGATACGCGTGGAGCGGTGCCTTTACAGATCCTAAGCCTTCCGCTAATATGGTTCTTGTAGCTGCTCCGGCCAAGCCGGAGGGCTACTCGTTCGACAAGGACTTTGACTTTGTTGAGTACAAGCCAGCACACATCACCAACGTCATGCGTGCTGTGGACAATCCGGATGAGGTGGTCTTCCCACCATATCCTGAGAAGTCCGTCATCCACCAGTTTGACGCCAAAGCCAAGAACCCCTCTCTTGACGGAGTGATCAACCACTTCCAGACAGAGCGTCCCGGAAACGAGACGAGCGCTCACTTCGGTATCTCCGGAGATCGAATCGTTCAGTTCGTGTCTCTAAAGGATCGAGCCTACCATGCTGGTAAGGTCGGAAACGACTACATTGGTATCGAGACTGATCCTCAACAGGATGCTGCTACCATTGAGTCAACGAAGAAGCTTCTTCGAGCGCTCAAGGCGAAGTATGGCTATGAGCTTATCACCGTTCTCCACAAGGATGTTCCCGGAAACACTACAAACTGTGGTGTTGAGATCAACCTTGAGAACTACGAACTGAACTCAGTTTCACCGACTCCTGTTCCACCTATCATCGTGGTTCCGGAGCCGACACCAGCCCCGACACCGGCCCCAACTCCGGCTGTCGATGAGGAAGCCGTAATTGACGCTTTCCTCGCCCACCTCAAAGAAGAGTTCTTCAAAACGAGGTAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0004222 metalloendopeptidase activity molecular function None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (PX4F) rather than this protein.
PDB ID
PX4F
Method AlphaFoldv2
Resolution 87.47
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50